Between-strain differences in hypothermic response in mice after intranasal administration of PtO nanoparticles

Air pollution by particulate matter (PM) has been associated with cardiopulmonary morbidity and mortality in many recent epidemiological studies. It has been shown that transition metal compounds, well- known toxic components of PM, are able to induce hypothermia following whole-body inhalation exposure. Low temperature appears to protect tissue against toxic effects of PM metal compounds in vivo and in vitro. To study the role of soluble and insoluble irritants in the induction of the hypothermic response, we analyz­ed the decrease in mouse body temperature (Δtbody) after intranasal administration of PtO nanoparticles or a K2[PtCl 4] solution. Between-strain differences in Δtbody after intranasal administration of the irritants were evaluated using 6 inbred (BALB/cJ, C57BL/6J, AKR/OlaHsd, DBA/2JRccHsd, C3H/HeNHsd, and SJL/J) and 2 outbred mouse strains (SCID and CD1). BALB/cJ and SCID mice showed the most pronounced effect of intranasal admini­stration of the xenobiotic on tbody. Thus, tbody was signi­ficantly lower after nasal administration the PtO nano­particles than after administration of the K2[PtCl 4] solution. To study the mechanism of this decrease, we compar­ed the respective values for Δtbody following intra­nasal, intravenous and peroral administration of PtO nanoparticles in Balb/c mice. Neither intravenous nor peroral administration had any effect on mouse body temperature. This fact together with data on the dynamics of the decrease in mouse body temperature following intranasal administration of PtO nanoparticles (max Δtbody ~ 80–100 min) allowed us to assume that this process is under nervous regulation. The correlation found between our data and some well-known phenotypic characteristics (phenome.jax.org) of the mouse strains used confirms this hypothesis

Atmospheric bistatic communication channels with scattering. Part 2. Field Experiments in 2013

Results of field experiments on the influence of atmospheric conditions and some instrumental characteristics on the quality of information transfer in a bistatic optoelectronic communication system (OECS) operating in the visible wavelengths range are considered. The length of the atmospheric channel reached 17 km. Radiation of a copper bromide vapor laser with a wavelength of 510.6 nm was used as a signal source. It is shown that bistatic or over-the-horizon OECSs can operate both under the conditions of a cloudy and cloud-free atmosphere. Average values and standard deviations of communication errors were estimated under different atmospheric-optical conditions when some characteristics of individual instrumentation units varied

Optimization of the Sample Preparation Procedure and Determination of the Content of REE and Ge in Low Carbonized Rocks by the ISP-MS Method Using a Triple Quadrupole

В работе представлены результаты исследований химического состава образцов лигнита Касского месторождения методом масс-спектрометрии с индуктивно связанной плазмой (ИСП-МС) с акцентом на определение редкоземельных элементов и германия. С учетом данных термогравиметрического анализа (ТГА) оптимизированы условия пробоподготовки образца с применением микроволнового разложения и механохимической активации, обеспечивающих практически полную минерализацию проб. Разработана методика ИСП-МС‑определения германия и РЗЭ в лигните на приборе “Agillent 8800” с тройным квадруполем и оценены ее метрологические характеристики. Показано, что лигниты Касского месторождения характеризуются содержанием германия и РЗЭ в количествах, перспективных для промышленного извлеченияThe paper presents the results of investigations of the chemical composition of lignite samples from the Kasskoye deposit by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) with an emphasis on the determination of rare earth elements (REE) and germanium. Taking into account the data of thermogravimetric analysis (TGA), the conditions for sample preparation were optimized using microwave decomposition and mechanochemical activation, which ensure almost complete mineralization of the samples. An ICP-MS method was developed for the determination of germanium and REE in lignite on an Agillent 8800 device with a triple quadrupole, and its metrological characteristics were evaluated. It is shown that the lignites of the Kass deposit are characterized by the content of germanium and REE in quantities that are promising for industrial extractio

Absorption of Terahertz Radiation in Ge/Si(001) Heterostructures with Quantum Dots

The terahertz spectra of the dynamic conductivity and radiation absorption coefficient in germanium-silicon heterostructures with arrays of Ge hut clusters (quantum dots) have been measured for the first time in the frequency range of 0.3-1.2 THz at room temperature. It has been found that the effective dynamic conductivity and effective radiation absorption coefficient in the heterostructure due to the presence of germanium quantum dots in it are much larger than the respective quantities of both the bulk Ge single crystal and Ge/Si(001) without arrays of quantum dots. The possible microscopic mechanisms of the detected increase in the absorption in arrays of quantum dots have been discussed.Comment: 9 pages, 4 figures; typos correcte