AFLP loci

The zip file contains three sheets of AFLP loci of Kandelia obovata, the neutral loci, the negative-outlier loci, and the positive outlier loci

Proportion of the sample that developed the kidney function decline by ABI categories.

<p>Proportion of the sample that developed the kidney function decline by ABI categories.</p

Association of Ankle-Brachial Index(ABI) with early-stage CKD.

<p>Abbreviations: CI, confidence interval; OR, odds ratio.</p><p>*The following covariates ascertained at baseline were included in multivariate analysis: age, sex, the history of hypertension, the duration of diabetes, smoking status, complications including diabetic neuropathy and retinopathy, body mass index, HbA1c, HDL and LDL cholesterol values, triglyceride levels.</p>#<p>The following covariates ascertained at baseline were included in regression analysis: age, sex, the history of hypertension, the duration of diabetes, smoking status, complications including diabetic neuropathy and retinopathy, BMI, triglyceride and C reactive protein levels.</p><p>Association of Ankle-Brachial Index(ABI) with early-stage CKD.</p

Characteristics of the participants with different ABI categories.

<p>*<i>P</i><0.05, **<i>P</i><0.001 compared with group of normal ABI.</p>†<p><i>P</i><0.05,</p>††<p><i>P</i><0.001 compared with group of low-normal ABI.</p><p>Abbreviations: BMI: body mass index; BP: blood pressure; MA: microalbminurine; FBG: fasting blood glucose; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; LDL-c: Low-density lipoprotein cholesterol.</p><p>Characteristics of the participants with different ABI categories.</p

Characteristics of the participants with normal or mildly decreased eGFR levels.

<p>Abbreviations: BMI: body mass index; BP: blood pressure; MA: microalbminurine; FBG: fasting blood glucose; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; LDL-c: Low-density lipoprotein cholesterol;</p><p>None: the patients never took anti-diabetic drugs. Both: the patients were taking oral drugs and subcutaneous injection of insulin at the same time.</p><p>Unless otherwise indicated, data are reported as mean ± SD. The referent category for <i>P</i> value comparisons is eGFR higher than 90 mL/min/1.73 m².</p><p>Characteristics of the participants with normal or mildly decreased eGFR levels.</p

The distribution of ABI categories in two groups according to the eGFR level.

<p>The distribution of ABI categories in two groups according to the eGFR level.</p

Additional file 1 of NOD1 deficiency ameliorates the progression of diabetic retinopathy by modulating bone marrow–retina crosstalk

Additional file 1. Supplementary data