1 research outputs found
Risk Assessment of Human Exposure to Bioaccessible Phthalate Esters via Indoor Dust around the Pearl River Delta
There is limited information on the bioaccessible fractions
of
phthalate esters in indoor dust in order to estimate human exposure.
In the present study, workplace dust and settled house dust samples
from Hong Kong, Shenzhen, and Guangzhou, the three major cities scattered
around the Pearl River Delta (PRD) were collected. Chemical analyses
showed that the phthalates in workplace dust ranged from 144 to 1810
μg/g, with dust from shopping malls containing the highest level,
and in home dust ranged from 181 to 9240 μg/g. The most abundant
phthalate ester found was bisÂ(2-ethylhexyl) phthalate (DEHP) in both
workplace dust and home dust, followed by di-<i>n</i>-butyl
phthalate (DBP) and di-iso-butyl phthalate (DIBP). Principal Components
Analysis (PCA) indicated that indoor dust around PRD showed similar
phthalate esters patterns of composition. A significant correlation
was observed between total phthalate esters concentrations in home
dust and the number of year of house construction (<i>p</i> < 0.05). The oral bioaccessibility of phthalate esters in indoor
dust ranged from 10.2% (DEHP) to 32% (DMP). Risk assessment indicated
that the dominant exposure routes varied in different phthalate esters
exposure profiles and the dermal contact exposure pathway was identified
as an important route for indoor DEHP exposure