335 research outputs found
Incorporating prior financial domain knowledge into neural networks for implied volatility surface prediction
In this paper we develop a novel neural network model for predicting implied
volatility surface. Prior financial domain knowledge is taken into account. A
new activation function that incorporates volatility smile is proposed, which
is used for the hidden nodes that process the underlying asset price. In
addition, financial conditions, such as the absence of arbitrage, the
boundaries and the asymptotic slope, are embedded into the loss function. This
is one of the very first studies which discuss a methodological framework that
incorporates prior financial domain knowledge into neural network architecture
design and model training. The proposed model outperforms the benchmarked
models with the option data on the S&P 500 index over 20 years. More
importantly, the domain knowledge is satisfied empirically, showing the model
is consistent with the existing financial theories and conditions related to
implied volatility surface.Comment: 8 pages, SIGKDD 202
A Gaussian variational inference approach to motion planning
We propose a Gaussian variational inference framework for the motion planning
problem. In this framework, motion planning is formulated as an optimization
over the distribution of the trajectories to approximate the desired trajectory
distribution by a tractable Gaussian distribution. Equivalently, the proposed
framework can be viewed as a standard motion planning with an entropy
regularization. Thus, the solution obtained is a transition from an optimal
deterministic solution to a stochastic one, and the proposed framework can
recover the deterministic solution by controlling the level of stochasticity.
To solve this optimization, we adopt the natural gradient descent scheme. The
sparsity structure of the proposed formulation induced by factorized objective
functions is further leveraged to improve the scalability of the algorithm. We
evaluate our method on several robot systems in simulated environments, and
show that it achieves collision avoidance with smooth trajectories, and
meanwhile brings robustness to the deterministic baseline results, especially
in challenging environments and tasks
Stochastic Motion Planning as Gaussian Variational Inference: Theory and Algorithms
We consider the motion planning problem under uncertainty and address it
using probabilistic inference. A collision-free motion plan with linear
stochastic dynamics is modeled by a posterior distribution. Gaussian
variational inference is an optimization over the path distributions to infer
this posterior within the scope of Gaussian distributions. We propose Gaussian
Variational Inference Motion Planner (GVI-MP) algorithm to solve this Gaussian
inference, where a natural gradient paradigm is used to iteratively update the
Gaussian distribution, and the factorized structure of the joint distribution
is leveraged. We show that the direct optimization over the state distributions
in GVI-MP is equivalent to solving a stochastic control that has a closed-form
solution. Starting from this observation, we propose our second algorithm,
Proximal Gradient Covariance Steering Motion Planner (PGCS-MP), to solve the
same inference problem in its stochastic control form with terminal
constraints. We use a proximal gradient paradigm to solve the linear stochastic
control with nonlinear collision cost, where the nonlinear cost is iteratively
approximated using quadratic functions and a closed-form solution can be
obtained by solving a linear covariance steering at each iteration. We evaluate
the effectiveness and the performance of the proposed approaches through
extensive experiments on various robot models. The code for this paper can be
found in https://github.com/hzyu17/VIMP.Comment: 19 page
Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3.
Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration. While significant progress has been made in understanding of molecular mechanisms of hESC differentiation into mesodermal cells, little is known about epigenetic factors controlling hESC fate toward mesoderm and MSCs. Identifying potential epigenetic factors that control hESC differentiation will undoubtedly lead to advancements in regenerative medicine. Here, we conducted an epigenome-wide analysis of hESCs and MSCs and uncovered that EZH2 was enriched in hESCs and was downregulated significantly in MSCs. The specific EZH2 inhibitor GSK126 directed hESC differentiation toward mesoderm and generated more MSCs by reducing H3K27me3. Our results provide insights into epigenetic landscapes of hESCs and MSCs and suggest that inhibiting EZH2 promotes mesodermal differentiation of hESCs
Sketch-a-Net that Beats Humans
We propose a multi-scale multi-channel deep neural network framework that,
for the first time, yields sketch recognition performance surpassing that of
humans. Our superior performance is a result of explicitly embedding the unique
characteristics of sketches in our model: (i) a network architecture designed
for sketch rather than natural photo statistics, (ii) a multi-channel
generalisation that encodes sequential ordering in the sketching process, and
(iii) a multi-scale network ensemble with joint Bayesian fusion that accounts
for the different levels of abstraction exhibited in free-hand sketches. We
show that state-of-the-art deep networks specifically engineered for photos of
natural objects fail to perform well on sketch recognition, regardless whether
they are trained using photo or sketch. Our network on the other hand not only
delivers the best performance on the largest human sketch dataset to date, but
also is small in size making efficient training possible using just CPUs.Comment: Accepted to BMVC 2015 (oral
Efficient Belief Road Map for Planning Under Uncertainty
Robotic systems, particularly in demanding environments like narrow corridors
or disaster zones, often grapple with imperfect state estimation. Addressing
this challenge requires a trajectory plan that not only navigates these
restrictive spaces but also manages the inherent uncertainty of the system. We
present a novel approach for graph-based belief space planning via the use of
an efficient covariance control algorithm. By adaptively steering state
statistics via output state feedback, we efficiently craft a belief roadmap
characterized by nodes with controlled uncertainty and edges representing
collision-free mean trajectories. The roadmap's structured design then paves
the way for precise path searches that balance control costs and uncertainty
considerations. Our numerical experiments affirm the efficacy and advantage of
our method in different motion planning tasks. Our open-source implementation
can be found at https://github.com/hzyu17/VIMP/tree/BRM
Diversity and Sparsity: A New Perspective on Index Tracking
We address the problem of partial index tracking, replicating a benchmark
index using a small number of assets. Accurate tracking with a sparse portfolio
is extensively studied as a classic finance problem. However in practice, a
tracking portfolio must also be diverse in order to minimise risk -- a
requirement which has only been dealt with by ad-hoc methods before. We
introduce the first index tracking method that explicitly optimises both
diversity and sparsity in a single joint framework. Diversity is realised by a
regulariser based on pairwise similarity of assets, and we demonstrate that
learning similarity from data can outperform some existing heuristics. Finally,
we show that the way we model diversity leads to an easy solution for sparsity,
allowing both constraints to be optimised easily and efficiently. we run
out-of-sample backtesting for a long interval of 15 years (2003 -- 2018), and
the results demonstrate the superiority of the proposed algorithm.Comment: Accepted to ICASSP 2020. 5 pages. This is a conference version of the
work, for the full version, please refer to arXiv:1809.01989v
Norovirus GII.17: The Emergence and Global Prevalence of a Novel Variant
A rare norovirus (NoV) genotype GII.17 has recently emerged and rapidly became predominant in most East Asian countries in the winters of 2014–2015. In this study, we report the diversity of NoV GII.17 in detail; a total of 646 GII.17 sequences obtained during 1978–2015 were analyzed and subjected to meta-analysis. At least five major recombinant GII.17 clusters were identified. Each recombinant variant group appeared to have emerged following the time order: GII.P4-GII.17 (1978–1990), GII.P16-GII.17 (2001–2004), GII.P13-GII.17 (2004–2010), GII.Pe-GII.17 (2012–2015) and GII.P3-GII.17 (2011–2015). The newly emerged GII.P3-GII.17 variant, which exhibited significant sequence and structure variations, is evolving toward a unique lineage. Our results indicate that circulation of GII.17 appears to change every 3–5 years due to replacement by a newly emerged variant and that the evolution of GII.17 is sequentially promoted by inter-genotype recombination, which contributes to the exchange between non-GII.17 and GII.17 RdRp genes and drives the evolution of GII.17 capsid genes
Forcing the Whole Video as Background: An Adversarial Learning Strategy for Weakly Temporal Action Localization
With video-level labels, weakly supervised temporal action localization
(WTAL) applies a localization-by-classification paradigm to detect and classify
the action in untrimmed videos. Due to the characteristic of classification,
class-specific background snippets are inevitably mis-activated to improve the
discriminability of the classifier in WTAL. To alleviate the disturbance of
background, existing methods try to enlarge the discrepancy between action and
background through modeling background snippets with pseudo-snippet-level
annotations, which largely rely on artificial hypotheticals. Distinct from the
previous works, we present an adversarial learning strategy to break the
limitation of mining pseudo background snippets. Concretely, the background
classification loss forces the whole video to be regarded as the background by
a background gradient reinforcement strategy, confusing the recognition model.
Reversely, the foreground(action) loss guides the model to focus on action
snippets under such conditions. As a result, competition between the two
classification losses drives the model to boost its ability for action
modeling. Simultaneously, a novel temporal enhancement network is designed to
facilitate the model to construct temporal relation of affinity snippets based
on the proposed strategy, for further improving the performance of action
localization. Finally, extensive experiments conducted on THUMOS14 and
ActivityNet1.2 demonstrate the effectiveness of the proposed method.Comment: 9 pages, 5 figures, conferenc
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