43 research outputs found
Second-Harmonic Generation and Spectrum Modulation by Active Nonlinear Metamaterial
The nonlinear properties of a metamaterial sample composed of double-layer
metallic patterns and voltage controllable diodes are experimentally
investigated. Second harmonics and spectrum modulations are clearly observed in
a wide band of microwave frequencies, showing that this kind of metamaterial is
not only tunable by low DC bias voltage, but also behaves strong nonlinear
property under a small power incidence. These properties are difficult to be
found in normal, naturally occurring materials.Comment: 14 pages, 4 figure
Dzyaloshinskii-Moriya interaction and magnetic skyrmions induced by curvature
Realizing sizeable Dzyaloshinskii-Moriya interaction (DMI) in intrinsic
two-dimensional (2D) magnets without any manipulation will greatly enrich
potential application of spintronics devices. The simplest and most desirable
situation should be 2D magnets with intrinsic DMI and intrinsic chiral spin
textures. Here, we propose to realize DMI by designing periodic ripple
structures with different curvatures in low-dimensional magnets and demonstrate
the concept in both one-dimensional (1D) CrBr2 and two-dimensional (2D) MnSe2
magnets by using first-principles calculations. We find that DMIs in curved
CrBr2 and MnSe2 can be efficiently controlled by varying the size of curvature
c, where c is defined as the ratio between the height h and the length l of
curved structure. Moreover, we unveil that the dependence of first-principles
calculated DMI on size of curvature c can be well described by the three-site
Fert-L\'evy model. At last, we uncover that field-free magnetic skyrmions can
be realized in curved MnSe2 by using atomistic spin model simulations based on
first-principles calculated magnetic parameters. The work will open a new
avenue for inducing DMI and chiral spin textures in simple 2D magnets via
curvature.Comment: Published on Physical Review B 106, 05442
PALMD regulates aortic valve calcification via altered glycolysis and NF-κB-mediated inflammation
Recent genome-wide association and transcriptome-wide association studies have identified an association between the PALMD locus, encoding palmdelphin, a protein involved in myoblast differentiation, and calcific aortic valve disease (CAVD). Nevertheless, the function and underlying mechanisms of PALMD in CAVD remain unclear. We herein investigated whether and how PALMD affects the pathogenesis of CAVD using clinical samples from CAVD patients and a human valve interstitial cell (hVIC) in vitro calcification model. We showed that PALMD was upregulated in calcified regions of human aortic valves and calcified hVICs. Furthermore, silencing of PALMD reduced hVIC in vitro calcification, osteogenic differentiation, and apoptosis, whereas overexpression of PALMD had the opposite effect. RNA-Seq of PALMD-depleted hVICs revealed that silencing of PALMD reduced glycolysis and nuclear factor-κB (NF-κB)–mediated inflammation in hVICs and attenuated tumor necrosis factor α–induced monocyte adhesion to hVICs. Having established the role of PALMD in hVIC glycolysis, we examined whether glycolysis itself could regulate hVIC osteogenic differentiation and inflammation. Intriguingly, the inhibition of PFKFB3-mediated glycolysis significantly attenuated osteogenic differentiation and inflammation of hVICs. However, silencing of PFKFB3 inhibited PALMD-induced hVIC inflammation, but not osteogenic differentiation. Finally, we showed that the overexpression of PALMD enhanced hVIC osteogenic differentiation and inflammation, as opposed to glycolysis, through the activation of NF-κB. The present study demonstrates that the genome-wide association– and transcriptome-wide association–identified CAVD risk gene PALMD may promote CAVD development through regulation of glycolysis and NF-κB–mediated inflammation. We propose that targeting PALMD-mediated glycolysis may represent a novel therapeutic strategy for treating CAVD
Effects of Plasma ZrN Metallurgy and Shot Peening Duplex Treatment on Fretting Wear and Fretting Fatigue Behavior of Ti6Al4V Alloy
A metallurgical zirconium nitride (ZrN) layer was fabricated using glow metallurgy using nitriding with zirconiuming prior treatment of the Ti6Al4V alloy. The microstructure, composition and microhardness of the corresponding layer were studied. The influence of this treatment on fretting wear (FW) and fretting fatigue (FF) behavior of the Ti6Al4V alloy was studied. The composite layer consisted of an 8-μm-thick ZrN compound layer and a 50-μm-thick nitrogen-rich Zr–Ti solid solution layer. The surface microhardness of the composite layer is 1775 HK0.1. A gradient in cross-sectional microhardness distribution exists in the layer. The plasma ZrN metallurgical layer improves the FW resistance of the Ti6Al4V alloy, but reduces the base FF resistance. This occurs because the improvement in surface hardness results in lowering of the toughness and increasing in the notch sensitivity. Compared with shot peening treatment, plasma ZrN metallurgy and shot peening composite treatment improves the FW resistance and enhances the FF resistance of the Ti6Al4V alloy. This is attributed to the introduction of a compressive stress field. The combination of toughness, strength, FW resistance and fatigue resistance enhance the FF resistance for titanium alloy
Cure Behavior and Thermomechanical Properties of Phthalonitrile–Polyhedral Oligomeric Silsesquioxane Copolymers
Phthalonitrile–polyhedral oligomeric silsesquioxane (POSS) copolymers were prepared by adding two different POSS cage mixtures: epoxycyclohexyl POSS (EP0408) and N-phenylaminopropyl POSS (AM0281). The cure behavior and properties of these polymers were analyzed and compared using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), dynamic mechanical analysis (DMA), Fourier transform far infrared (FTIR) measurements, and rheometric studies. The POSS-containing polymers showed higher chemical reactivity, better thermal stability and better mechanical performance in comparison to their unmodified counterparts. All the polymers showed water absorption below 1.5%. As revealed by FTIR measurements, the polymerization products contained triazine ring structures that were responsible for the superior thermal properties exhibited by these POSS-containing polymers