1,655 research outputs found

    Titan photometric parameters

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    Measurements of the irradiance of Titan from 0.05 to 1.08 micrometer were carried out by 60-inch reflector, spectrometer, and pulse counting electronics. An approximate contour of the geometric albedo assumes methane is the principal absorber. The albedo of Titan reaches a maximum value of 0.37 at 0.68, 0.753, and 0.83 micrometers, while in the center of the strongest absorption features, at 0.89 and 1.0. micrometer, it falls to 0.10. Comparison with the methane bands of Jupiter and Saturn indicates that the maxima clearly do not represent the continuum and that the lower values may well be depressed by wings of methane bands adjacent to them

    HIV treatment failure; ART toxicity & complications

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    This is Session 2 in the PEER Liberia HIV/Viral Hepatitis Lecture Series. This presentation provides an overview of HIV antiretroviral therapy, treatment monitoring, failure and complications

    Focused Review of Antiretroviral Treatment

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    This presentation is a review of Sessions 1 and 2 in the PEER Liberia HIV/Viral Hepatitis Lecture Series and provides an overview of HIV antiretroviral therapy and complications

    Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice

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    The amino acid sequence of amyloid precursor protein (APP) is highly conserved, and age-related Abeta aggregates have been described in a variety of vertebrate animals, with the notable exception of mice and rats. Three amino acid substitutions distinguish mouse and human Abeta that might contribute to their differing properties in vivo. To examine the amyloidogenic potential of mouse Abeta, we studied several lines of transgenic mice overexpressing wild-type mouse amyloid precursor protein (moAPP) either alone or in conjunction with mutant PS1 (PS1dE9). Neither overexpression of moAPP alone nor co-expression with PS1dE9 caused mice to develop Alzheimer-type amyloid pathology by 24 months of age. We further tested whether mouse Abeta could accelerate the deposition of human Abeta by crossing the moAPP transgenic mice to a bigenic line expressing human APPswe with PS1dE9. The triple transgenic animals (moAPP x APPswe/PS1dE9) produced 20% more Abeta but formed amyloid deposits no faster and to no greater extent than APPswe/PS1dE9 siblings. Instead, the additional mouse Abeta increased the detergent solubility of accumulated amyloid and exacerbated amyloid deposition in the vasculature. These findings suggest that, although mouse Abeta does not influence the rate of amyloid formation, the incorporation of Abeta peptides with differing sequences alters the solubility and localization of the resulting aggregates

    Opportunistic Infections, & Hepatitis B treatment & monitoring

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    This is Session 3 in the PEER Liberia HIV/Viral Hepatitis Lecture Series. This presentation provides an overview of HIV opportunistic infections and Hepatitis B treatment and monitoring

    Overview & History of HIV: Epidemiology, ART, 1st line treatment & monitoring

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    This is Session 1 in the PEER Liberia HIV/Viral Hepatitis Lecture Series. This presentation provides an overview and history of HIV, including epidemiology, testing, treatment and monitoring

    Glad-irons Replace Sad-irons

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    Remember the old sadirons whose heat you judged by the ferocity of the sizzle? Equipment needed for those days of ironing drudgery included- a strong right arm, a gaily colored calico holder to protect your hand from the hot handle, yesterday\u27s newspaper for a stand, and a piece of wax to keep the bottom of the iron smooth. Then there was the big, heavy ironing board- one end resting on the kitchen table and the other on a stool on which perhaps the cookie box was set and maybe an old encyclopedia to give the necessary height
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