CoMon: Cooperative Ambience Monitoring Platform with Continuity and Benefit Awareness

Mobile applications that sense continuously, such as location monitoring, are emerging. Despite their usefulness, their adoption in real-world deployment situations has been extremely slow. Many smartphone users are turned away by the drastic battery drain caused by continuous sensing and processing. Also, the extractable contexts from the phone are quite limited due to its position and sensing modalities. In this paper, we propose CoMon, a novel cooperative ambience monitoring platform, which newly addresses the energy problem through opportunistic cooperation among nearby mobile users. To maximize the benefit of cooperation, we develop two key techniques, (1) continuity-aware cooperator detection and (2) benefit-aware negotiation. The former employs heuristics to detect cooperators who will remain in the vicinity for a long period of time, while the latter automatically devises a cooperation plan that provides mutual benefit to cooperators, while considering running applications, available devices, and user policies. Through continuity- and benefit-aware operation, CoMon enables applications to monitor the environment at much lower energy consumption. We implement and deploy a CoMon prototype and show that it provides significant benefit for mobile sensing applications

AEROKEY: Using Ambient Electromagnetic Radiation for Secure and Usable Wireless Device Authentication

Wireless connectivity is becoming common in increasingly diverse personal devices, enabling various interoperation- and Internet-based applications and services. More and more interconnected devices are simultaneously operated by a single user with short-lived connections, making usable device authentication methods imperative to ensure both high security and seamless user experience. Unfortunately, current authentication methods that heavily require human involvement, in addition to form factor and mobility constraints, make this balance hard to achieve, often forcing users to choose between security and convenience. In this work, we present a novel over-the-air device authentication scheme named AEROKEY that achieves both high security and high usability. With virtually no hardware overhead, AEROKEY leverages ubiquitously observable ambient electromagnetic radiation to autonomously generate spatiotemporally unique secret that can be derived only by devices that are closely located to each other. Devices can make use of this unique secret to form the basis of a symmetric key, making the authentication procedure more practical, secure and usable with no active human involvement. We propose and implement essential techniques to overcome challenges in realizing AEROKEY on low-cost microcontroller units, such as poor time synchronization, lack of precision analog front-end, and inconsistent sampling rates. Our real-world experiments demonstrate reliable authentication as well as its robustness against various realistic adversaries with low equal-error rates of 3.4% or less and usable authentication time of as low as 24 s

Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

Background Measurement of γ-H2AX foci levels in cells provides a sensitive and reliable method for quantitation of the radiation-induced DNA damage response. The objective of the present study was to develop a rapid, high-throughput γ-H2AX assay based on imaging flow cytometry (IFC) using the ImageStream®X Mk II (ISX) platform to evaluate DNA double strand break (DSB) repair kinetics in human peripheral blood cells after exposure to ionizing irradiation. Methods The γ-H2AX protocol was developed and optimized for small volumes (100 μL) of human blood in Matrix™ 96-tube format. Blood cell lymphocytes were identified and captured by ISX INSPIRE™ software and analyzed by Data Exploration and Analysis Software. Results Dose- and time-dependent γ-H2AX levels corresponding to radiation exposure were measured at various time points over 24 h using the IFC system. γ-H2AX fluorescence intensity at 1 h after exposure, increased linearly with increasing radiation dose (R2 = 0.98) for the four human donors tested, whereas the dose response for the mean number of γ-H2AX foci/cell was not as robust (R2 = 0.81). Radiation-induced γ-H2AX levels rapidly increased within 30 min and reached a maximum by ~ 1 h, after which time there was fast decline by 6 h, followed by a much slower rate of disappearance up to 24 h. A mathematical approach for quantifying DNA repair kinetics using the rate of γ-H2AX decay (decay constant, Kdec), and yield of residual unrepaired breaks (Fres) demonstrated differences in individual repair capacity between the healthy donors. Conclusions The results indicate that the IFC-based γ-H2AX protocol may provide a practical and high-throughput platform for measurements of individual global DNA DSB repair capacity which can facilitate precision medicine by predicting individual radiosensitivity and risk of developing adverse effects related to radiotherapy treatment

Establishing Trust in Vehicle-to-Vehicle Coordination: A Sensor Fusion Approach

Autonomous vehicles (AVs) use diverse sensors to understand their surroundings as they continually make safety- critical decisions. However, establishing trust with other AVs is a key prerequisite because safety-critical decisions cannot be made based on data shared from untrusted sources. Existing protocols require an infrastructure network connection and a third-party root of trust to establish a secure channel, which are not always available. In this paper, we propose a sensor-fusion approach for mobile trust establishment, which combines GPS and visual data. The combined data forms evidence that one vehicle is nearby another, which is a strong indication that it is not a remote adversary hence trustworthy. Our preliminary experiments show that our sensor-fusion approach achieves above 80% successful pairing of two legitimate vehicles observing the same object with 5 meters of error. Based on these preliminary results, we anticipate that a refined approach can support fuzzy trust establishment, enabling better collaboration between nearby AVs

Establishing Trust in Vehicle-to-Vehicle Coordination: A Sensor Fusion Approach

As we add more autonomous and semi-autonomous vehicles (AVs) to our roads, their effects on passenger and pedestrian safety are becoming more important. Despite extensive testing, AVs do not always identify roadway hazards. Failures in object recognition components have already led to several fatal collisions, e.g. as a result of faults in sensors, software, or vantage point. Although a particular AV may fail, there is an untapped pool of information held by other AVs in the vicinity that could be used to identify roadway hazards before they present a safety threat

The immediate upstream region of the 5 0 -UTR from the AUG start codon has a pronounced effect on the translational efficiency in Arabidopsis thaliana

ABSTRACT The nucleotide sequence around the translational initiation site is an important cis-acting element for post-transcriptional regulation. However, it has not been fully understood how the sequence context at the 5 0 -untranslated region (5 0 -UTR) affects the translational efficiency of individual mRNAs. In this study, we provide evidence that the 5 0 -UTRs of Arabidopsis genes showing a great difference in the nucleotide sequence vary greatly in translational efficiency with more than a 200-fold difference. Of the four types of nucleotides, the A residue was the most favourable nucleotide from positions À1 to À21 of the 5 0 -UTRs in Arabidopsis genes. In particular, the A residue in the 5 0 -UTR from positions À1 to À5 was required for a high-level translational efficiency. In contrast, the T residue in the 5 0 -UTR from positions À1 to À5 was the least favourable nucleotide in translational efficiency. Furthermore, the effect of the sequence context in the À1 to À21 region of the 5 0 -UTR was conserved in different plant species. Based on these observations, we propose that the sequence context immediately upstream of the AUG initiation codon plays a crucial role in determining the translational efficiency of plant genes