3,475 research outputs found
Atomtronics with a spin: statistics of spin transport and non-equilibrium orthogonality catastrophe in cold quantum gases
We propose to investigate the full counting statistics of nonequilibrium spin
transport with an ultracold atomic quantum gas. The setup makes use of the spin
control available in atomic systems to generate spin transport induced by an
impurity atom immersed in a spin-imbalanced two-component Fermi gas. In
contrast to solid-state realizations, in ultracold atoms spin relaxation and
the decoherence from external sources is largely suppressed. As a consequence,
once the spin current is turned off by manipulating the internal spin degrees
of freedom of the Fermi system, the nonequilibrium spin population remains
constant. Thus one can directly count the number of spins in each reservoir to
investigate the full counting statistics of spin flips, which is notoriously
challenging in solid state devices. Moreover, using Ramsey interferometry, the
dynamical impurity response can be measured. Since the impurity interacts with
a many-body environment that is out of equilibrium, our setup provides a way to
realize the non-equilibrium orthogonality catastrophe. Here, even for spin
reservoirs initially prepared in a zero-temperature state, the Ramsey response
exhibits an exponential decay, which is in contrast to the conventional
power-law decay of Anderson's orthogonality catastrophe. By mapping our system
to a multi-step Fermi sea, we are able to derive analytical expressions for the
impurity response at late times. This allows us to reveal an intimate
connection of the decay rate of the Ramsey contrast and the full counting
statistics of spin flips.Comment: 9+11 pages, 10 figure
Cy3 and Cy5 dyes attached to oligonucleotide terminus stabilize DNA duplexes: Predictive thermodynamic model
AbstractCyanine dyes are important chemical modifications of oligonucleotides exhibiting intensive and stable fluorescence at visible light wavelengths. When Cy3 or Cy5 dye is attached to 5Ⲡend of a DNA duplex, the dye stacks on the terminal base pair and stabilizes the duplex. Using optical melting experiments, we have determined thermodynamic parameters that can predict the effects of the dyes on duplex stability quantitatively (ÎG°, Tm). Both Cy dyes enhance duplex formation by 1.2kcal/mol on average, however, this Gibbs energy contribution is sequence-dependent. If the Cy5 is attached to a pyrimidine nucleotide of pyrimidineâpurine base pair, the stabilization is larger compared to the attachment to a purine nucleotide. This is likely due to increased stacking interactions of the dye to the purine of the complementary strand. Dangling (unpaired) nucleotides at duplex terminus are also known to enhance duplex stability. Stabilization originated from the Cy dyes is significantly larger than the stabilization due to the presence of dangling nucleotides. If both the dangling base and Cy3 are present, their thermodynamic contributions are approximately additive. New thermodynamic parameters improve predictions of duplex folding, which will help design oligonucleotide sequences for biophysical, biological, engineering, and nanotechnology applications
What is the irrigation potential for Africa?
Although irrigation in Africa has the potential to boost agricultural productivities by at least 50 percent, food production on the continent is almost entirely rainfed. The area equipped for irrigation, currently slightly more than 13 million hectares, makes up just 6 percent of the total cultivated area. Eighty-five percent of Africaâs poor live in rural areas and mostly depend on agriculture for their livelihoods. As a result, agricultural development is key to ending poverty on the continent. Many development organizations have recently proposed to significantly increase investments in irrigation in the region. However, the potential for irrigation investments in Africa is highly dependent upon geographic, hydrologic, agronomic, and economic factors that need to be taken into account when assessing the long-term viability and sustainability of planned projects. This paper analyzes large, dam-based and small-scale irrigation investment needs in Africa based on agronomic, hydrologic, and economic factors. This type of analysis can guide country- and local-level assessment of irrigation potential, which will be important to agricultural and economic development in Africa.internal rate of return, Investment, irrigation potential, large-scale irrigation, small-scale irrigation,
Design of LNA probes that improve mismatch discrimination
Locked nucleic acids (LNA) show remarkable affinity and specificity against native DNA targets. Effects of LNA modifications on mismatch discrimination were studied as a function of sequence context and identity of the mismatch using ultraviolet (UV) melting experiments. A triplet of LNA residues centered on the mismatch was generally found to have the largest discriminatory power. An exception was observed for GâT mismatches, where discrimination decreased when the guanine nucleotide at the mismatch site or even the flanking nucleotides were modified. Fluorescence experiments using 2-aminopurine suggest that LNA modifications enhance base stacking of perfectly matched base pairs and decrease stabilizing stacking interactions of mismatched base pairs. LNAs do not change the amount of counterions (Na(+)) that are released when duplexes denature. New guidelines are suggested for design of LNA probes, which significantly improve mismatch discrimination in comparison with unmodified DNA probes
RePaint-NeRF: NeRF Editting via Semantic Masks and Diffusion Models
The emergence of Neural Radiance Fields (NeRF) has promoted the development
of synthesized high-fidelity views of the intricate real world. However, it is
still a very demanding task to repaint the content in NeRF. In this paper, we
propose a novel framework that can take RGB images as input and alter the 3D
content in neural scenes. Our work leverages existing diffusion models to guide
changes in the designated 3D content. Specifically, we semantically select the
target object and a pre-trained diffusion model will guide the NeRF model to
generate new 3D objects, which can improve the editability, diversity, and
application range of NeRF. Experiment results show that our algorithm is
effective for editing 3D objects in NeRF under different text prompts,
including editing appearance, shape, and more. We validate our method on both
real-world datasets and synthetic-world datasets for these editing tasks.
Please visit https://repaintnerf.github.io for a better view of our results.Comment: IJCAI 2023 Accepted (Main Track
Giant intradural cervical spine arteriovenous malformations â A case and review of literature
â˘Spinal arteriovenous malformations (SAVM) are very rare.â˘Therapeutic options can be very challenging since none of them provided a definitive cure to this lesion in literature.â˘Spinal angiography is the gold standard for all-inclusive assessment of SAVMs.â˘We believe that incorporation intraoperative angiography during surgery in a hybrid theatre can help achieve a better cure
Dual-Parameter Opto-Mechanical Fiber Optic Sensors for Harsh Environment Sensing: Design, Packaging, Calibration, and Applications
This thesis concerns with the development of a dual-parameter sensor based on fiber Bragg grating (FBG) and a packaging design for high pressure sensing in harsh environment.
This thesis starts by introducing a novel design of a partially coated FBG, using a metallic insert and a thermal curing epoxy. An analytical opto-mechanical model, based on couple mode theory, was developed and presented. The experimental and modelling result of the optical response of the partially coated FBG were compared and shown to be in excellent agreement. The experiments were executed on a custom-built fiber optic calibration station. The coated FBG sensor has a temperature sensitivity of 26.9 ¹ 0.3 pm/°C, which is 2.7 times higher than a bare fiber; and a force sensitivity of 0.104 nm/N, which is 13 times smaller than a bare fiber. The zero reference of the sensor has a drift of a maximum of 70 pm but the sensor is shown to settle within ¹5 pm after 3 thermal cycles and 10 tensile loading cycles.
A low profile packaging design is presented for a maximum pressure of 20.68 MPa (3000 psi) for harsh environment applications. A detailed study with FEM analysis revealed the optimal design for the packageâs sleeve thickness is 0.5 mm. The temperature sensitivity is in close agreement with the unpackaged coated sensor with 10% difference. Compared to the modelling, the equivalent force sensitivity is 27% lower due to prototype dimensional uncertainties and modelling uncertainties with the material properties. The lack of pre-tension of the FBG sensor in the package also attributed to lower force sensitivity at pressure level lower than 4.13 MPa (600 psi).1 yea
Chemical modification at and within nanopowders: Synthesis of coreâshell Al2O3@TiON nanopowders via nitriding nanoâ(TiO2)0.43(Al2O3)0.57 powders in NH3
Here, we demonstrate the potential utility of using chemical modification to reorganize metastable nanoparticles into nanostructured nanoparticles without coincidentally inducing extensive necking/sintering. The motivation for this effort derives from the concept that chemical reduction in a single component in a mixedâmetal nanoparticle will create segregated islands of a second immiscible phase. Given the very high chemical energies inherent in nanoparticles, the formation of even smaller islands of a second phase can be anticipated to lead to extremely high interfacial energies that may drive these islands to diffuse to cores or surfaces to form coreâshell structures that minimize such interfacial energies. Thus, ammonolysis of (TiO2)0.43(Al2O3)0.57 composition nanopowders where both elements are approximately uniformly mixed at atomic length scales, under selected conditions (1000°C) for various periods of time at constant NH3 flow rates leads primarily to the reduction in the Ti species to form TiN or TiON which then appears to diffuse to the surface of the particles. The final products consist of Al2O3@TiON coreâshell nanopowders that remain mostly unaggregated pointing to a new mechanism for modifying nanopowder chemistries and physical properties.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142336/1/jace15303_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142336/2/jace15303.pd
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