54 research outputs found
A proposal for new diagnostic criteria for ALS
© 2020 The Authors. Published by Elsevier B.V. on behalf of International Federation of Clinical Neurophysiology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Sclerosis (ALS) were initially published in 1994 and revised in 2000. Criteria were established because the ‘‘variety of clinical features which may be present early in the course of ALS makes absolute diagnosis difficult and compromises the certainty of diagnosis for clinical research purposes and therapeutic trials.” The original criteria described 4 categories of disease: Definite, Probable, Possible, and Suspected ALS. However, subsequent clinical experience made it clear that non-Definite categories included patients who would ultimately die of ALS with a high degree of clinical certainty.info:eu-repo/semantics/publishedVersio
Temporal changes in the population density and diet of brown bears in eastern Hokkaido, Japan
A Case of Paroxysmal Atrial Fibrillation Improved after the Administration of Proton Pump Inhibitor for Associated Reflux Esophagitis
The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis
The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis
Noncontact Mapping-Guided Catheter Ablation of Posterosuperior Right Atrial Tachycardia Associated with Sick Sinus Syndrome
Focal atrial tachycardia (AT) is sometimes associated with sick sinus syndrome. A 57-year-old female complained of palpitation, fatigue and presyncope. Ambulatory monitoring demonstrated frequent segments of AT and subsequent sinus arrests. P wave morphology of ectopic beats was similar to that of sinus rhythm. After obtaining diagnosis of bradycardia tachycardia syndrome, she underwent electrophysiologic study (EPS) and radiofrequency (RF) catheter ablation to eliminate AT.
Conventional EPS could not be performed due to frequent spontaneous ectopic beats. EnSite mapping demonstrated that AT originates from posterosuperior right atrium (RA) and that local electrogram of ectopic focus precedes the onset of P wave in surface ECG by 40 msec. After EnSite-guided RF ablation to the target area, ambulatory monitoring detected no AT or sinus arrest. EPS performed one week after RF ablation showed atropine-induced partial restoration of sinus node dysfunction.
Her symptoms were resolved remarkably and permanent pacemaker implantation has not been necessary to date. RF ablation guided by EnSite mapping was useful to eliminate AT arising from limited ectopic focus and this case implies existence of “pacemaker-avoidable” bradycardia tachycardia syndrome
- …