Changes in plasma levels of individual parameters during hemodialysis.

<p>(A–G) Individual changes in the levels of total BNP (A), proBNP (B), mature BNP (C), nonglycoNT-proBNP (D), glycoNT-proBNP (E), ANP (F) and cGMP (G) in ESRD patients during hemodialysis. Values are means ± SE. *p<0.001 vs. before hemodialysis. Before, before hemodialysis; After, after hemodialysis. (H) Reduction ratios for total BNP, proBNP, mature BNP, nonglycoNT-proBNP, glycoNT-proBNP, ANP and cGMP in ESRD patients during hemodialysis. Values are means ± SE.</p

Correlations between cGMP and natriuretic peptide-related molecules in ESRD patients before and after hemodialysis.

<p><i>R</i> is the correlation coefficient. Values are expressed as log₁₀ of each level of the indicated molecules.</p

ProBNP/total BNP ratios and their correlation with the indicated clinical parameters.

<p>(A) Individual changes in proBNP/total BNP ratios in ESRD patients during hemodialysis: Before, before hemodialysis; After, after hemodialysis. (B) ProBNP/total BNP ratios in ESRD patients during hemodialysis expressed as means ± SE. (C–F) Correlation between proBNP/total BN ratios and hemodialysis vintage (C), left atrial diameter (LAD) (D), systolic blood pressure before hemodialysis (preBPs) (E) and mean blood pressure before hemodialysis (pre mBP) (F). <i>R</i> is the correlation coefficient between the indicated parameters.</p

Correlation coefficients and p values relating changes in percent body weight or total body fluid volume to the percent reduction in natriuretic peptide-related molecules.

<p>r is the correlation coefficient.</p

Changes in plasma levels of individual parameters during hemodialysis.

<p>(A–G) Individual changes in the levels of total BNP (A), proBNP (B), mature BNP (C), nonglycoNT-proBNP (D), glycoNT-proBNP (E), ANP (F) and cGMP (G) in ESRD patients during hemodialysis. Values are means ± SE. *p<0.001 vs. before hemodialysis. Before, before hemodialysis; After, after hemodialysis. (H) Reduction ratios for total BNP, proBNP, mature BNP, nonglycoNT-proBNP, glycoNT-proBNP, ANP and cGMP in ESRD patients during hemodialysis. Values are means ± SE.</p

Clinical profiles of the healthy subjects and ESRD patients enrolled in this study.

<p>Clinical profiles of the healthy subjects and ESRD patients enrolled in this study.</p

NonglycoNT-proBNP and glycoproBNP levels, glycoNT-proBNP/nonglycoNT-proBNP ratios and correlations between glycoNT-proBNP/nonglycoNT-proBNP ratios and clinical parameters.

<p>(A, B) Circulating levels of nonglycoNT-proBNP and glycoNT-proBNP in ESRD patients before (A) and after (B) hemodialysis. Values are expressed means ± SE. (C, D) Individual changes and values of glycoNT-proBNP/nonglycoNT-proBNP ratios in ESRD patients during hemodialysis. Values are expressed as mean ± SE. *p<0.001 vs. before hemodialysis. before, before hemodialysis; after, after hemodialysis. (E) Reduction ratios for nonglycoNT-proBNP and glycoNT-proBNP during hemodialysis. *p<0.001 vs. nonglycoNT-proBNP. (F) Correlation between the glycoNT-proBNP/nonglycoNT-proBNP ratio and the serum parathyroid hormone (PTH) levels. <i>R</i> is the correlation coefficient.</p