733 research outputs found

    The Views of `Volunteer\u27 of Japanese University Students

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    A questionnaire survey was given to Japanese undergraduate students to determine their personal experiences of `volunteer activities\u27. And their views and images of `volunteer\u27 in Japan. The results showed that almost 80% experienced `volunteer activities\u27 in schools before entering university. The details of their experiences did not relate to their views and images of `volunteer\u27 and the `volunteer activities\u27 at schools did not seem to play an important role in developing the concept of `volunteer\u27 of young people. This study suggested the importance of learning `volunteer activities\u27 at schools

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    Programmable time-multiplexed squeezed light source

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    One of the leading approaches to large-scale quantum information processing (QIP) is the continuous-variable (CV) scheme based on time multiplexing (TM). As a fundamental building block for this approach, quantum light sources to sequentially produce time-multiplexed squeezed-light pulses are required; however, conventional CV TM experiments have used fixed light sources that can only output the squeezed pulses with the same squeezing levels and phases. We here demonstrate a programmable time-multiplexed squeezed light source that can generate sequential squeezed pulses with various squeezing levels and phases at a time interval below 100 ns. The generation pattern can be arbitrarily chosen by software without changing its hardware configuration. This is enabled by using a waveguide optical parametric amplifier and modulating its continuous pump light. Our light source will implement various large-scale CV QIP tasks.Comment: 14 pages, 7 figure

    Mice Transgenic for KitV620A: Recapitulation of Piebaldism but not Progressive Depigmentation Seen in Humans with this Mutation

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    Piebaldism is an autosomal dominant genetic pigmentary disorder, characterized by congenital white hair and patches located on the forehead, anterior trunk, and extremities. Most piebald patients have a mutation of the KIT gene, which encodes a tyrosine kinase receptor involved in pigment cell development. The white hair and patches of such patients are already completely formed at birth and do not usually expand thereafter. This stability of pigmented spots also applies to KitW and KitlSl mutant mice. However, two novel cases of piebaldism were reported in 2001, in which both mother and daughter having a novel Val620Ala mutation in their KIT gene showed progressive depigmentation. To prepare an animal model of this mutation, to explore undefined functions of KIT signaling for maintaining pigmented melanocytes in the skin or more specifically the integrity of the melanocyte stem cell system in the postnatal skin, we produced transgenic mice expressing Val620Ala Kit. These mice well mimicked the white spotting pattern of patients; however, no change in this pattern was observed after birth, even after increasing the transgene expression by various means. Here, we report the unexpectedly extremely stable maintenance of the melanocyte stem cell system under stringent conditions for KIT signaling
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