Additional file 1: Figure S1. of Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation

Sac-1004 increases HBMEC survival. HBMECs were starved and treated with various concentrations of Sac-1004. Chemical structure of Sac-1004 (A). Cell survival was detected using an MTT assay (B). Under the same experimental conditions, cell viability was also determined by microscopy after incubation for 48 h (C). All data are presented the means ± SEM. ***P < 0.001. (JPG 82 kb