6 research outputs found
Associations between SNPs in 9p22.2 with ovarian cancer risk for <i>BRCA1</i> and <i>BRCA2</i> mutation carriers.
- Author
- Alfons Meindl (112058)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Angel Izquierdo (3147192)
- Anna Jakubowska (146752)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Antoine de Pauw (196753)
- Antonis C. Antoniou (146788)
- Arjen R. Mensenkamp (2271544)
- Athanassios Vratimos (3147159)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Bruce Poppe (797)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Catherine M. Phelan (219497)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christina Edwinsdotter Ardnor (3147171)
- Christopher R. Hake (3147183)
- Claude Houdayer (395237)
- Claudine Isaacs (59927)
- Csilla I. Szabo (395202)
- D. Gareth Evans (154186)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Vigorito (141461)
- Elizabeth J. van Rensburg (395205)
- Eric A. Ross (3147168)
- Esther M. John (107266)
- Evgeny N. Imyanitov (395207)
- Fabienne Lesueur (10534)
- Fergus J. Couch (146607)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Grzegorz Sukiennicki (196615)
- Gustavo C. Rodriguez (395256)
- Heli Nevanlinna (83762)
- Ian Campbell (205212)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Jonathan Beesley (89897)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Judy Kirk (15511)
- Julian Adlard (395223)
- Kai-ren Ong (3147165)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen B. M. Claes (3147162)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Laima Tihomirova (196713)
- Laure Barjhoux (395412)
- Lauren Jacobs (484900)
- Lesley McGuffog (153865)
- Lidia Feliubadalo (3147198)
- Liliana Varesco (381200)
- Louise Izatt (69449)
- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Martine Dumont (553712)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Miquel Angel Pujana (395274)
- Muriel Belotti (395413)
- Muy-Kheng Tea (308359)
- Noralane Lindor (154074)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Patricia A. Ganz (395212)
- Paul D. P. Pharoah (146906)
- Penny Soucy (21792)
- Peter J. Hulick (3147177)
- Phuong L. Mai (238716)
- Pragna Gaddam (759099)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Ros Eeles (238725)
- Rosemarie Davidson (154164)
- Salina B. Chan (395287)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Sofia Khan (79890)
- Soo-Hwang Teo (266270)
- Sophie Giraud (3147180)
- Steve Ellis (395221)
- Sue Healey (41187)
- Sue Kyung Park (549838)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Sylvie Mazoyer (196744)
- Thomas P. Slavin (3147186)
- Thomas V. O. Hansen (395201)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vanesa Garcia-Barberan (3147174)
- William D. Foulkes (232312)
- Yael Laitman (196595)
- Ylva Paulsson-Karlsson (3147189)
- Publication venue
- Publication date
- Field of study
<p>In each plot, the purple diamond corresponds to the strongest associated SNP and the colour code indicates the linkage disequilibrium with respect to this variant. Horizontal lines indicate the -log<sub>10</sub> p-value such that the SNPs above the line are the potential causal ones. This set was defined based on a likelihood ratio for a particular SNP as being less or equal than 100, relative to the most likely variant and r<sup>2</sup>>0.1. (A) <i>BRCA1</i> mutation carriers, (B) <i>BRCA2</i> mutation carriers.</p
Pairwise correlations (r<sup>2</sup>) between selected SNPs.
- Author
- Alfons Meindl (112058)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Angel Izquierdo (3147192)
- Anna Jakubowska (146752)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Antoine de Pauw (196753)
- Antonis C. Antoniou (146788)
- Arjen R. Mensenkamp (2271544)
- Athanassios Vratimos (3147159)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Bruce Poppe (797)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Catherine M. Phelan (219497)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christina Edwinsdotter Ardnor (3147171)
- Christopher R. Hake (3147183)
- Claude Houdayer (395237)
- Claudine Isaacs (59927)
- Csilla I. Szabo (395202)
- D. Gareth Evans (154186)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Vigorito (141461)
- Elizabeth J. van Rensburg (395205)
- Eric A. Ross (3147168)
- Esther M. John (107266)
- Evgeny N. Imyanitov (395207)
- Fabienne Lesueur (10534)
- Fergus J. Couch (146607)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Grzegorz Sukiennicki (196615)
- Gustavo C. Rodriguez (395256)
- Heli Nevanlinna (83762)
- Ian Campbell (205212)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Jonathan Beesley (89897)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Judy Kirk (15511)
- Julian Adlard (395223)
- Kai-ren Ong (3147165)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen B. M. Claes (3147162)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Laima Tihomirova (196713)
- Laure Barjhoux (395412)
- Lauren Jacobs (484900)
- Lesley McGuffog (153865)
- Lidia Feliubadalo (3147198)
- Liliana Varesco (381200)
- Louise Izatt (69449)
- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Martine Dumont (553712)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Miquel Angel Pujana (395274)
- Muriel Belotti (395413)
- Muy-Kheng Tea (308359)
- Noralane Lindor (154074)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Patricia A. Ganz (395212)
- Paul D. P. Pharoah (146906)
- Penny Soucy (21792)
- Peter J. Hulick (3147177)
- Phuong L. Mai (238716)
- Pragna Gaddam (759099)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Ros Eeles (238725)
- Rosemarie Davidson (154164)
- Salina B. Chan (395287)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Sofia Khan (79890)
- Soo-Hwang Teo (266270)
- Sophie Giraud (3147180)
- Steve Ellis (395221)
- Sue Healey (41187)
- Sue Kyung Park (549838)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Sylvie Mazoyer (196744)
- Thomas P. Slavin (3147186)
- Thomas V. O. Hansen (395201)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vanesa Garcia-Barberan (3147174)
- William D. Foulkes (232312)
- Yael Laitman (196595)
- Ylva Paulsson-Karlsson (3147189)
- Publication venue
- Publication date
- Field of study
<p>SNPs correspond to: rs10124837, the strongest associated in <i>BRCA1</i>; rs62543583, the strongest associated in <i>BRCA2</i> mutation carriers; rs7046326, the strongest associated in <i>BRCA1/2</i> meta-analysis; rs3814113, was the strongest associated variant in the initial GWAS analysis.</p
Genomic features surrounding the 9p22.2 locus.
- Author
- Alfons Meindl (112058)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Angel Izquierdo (3147192)
- Anna Jakubowska (146752)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Antoine de Pauw (196753)
- Antonis C. Antoniou (146788)
- Arjen R. Mensenkamp (2271544)
- Athanassios Vratimos (3147159)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Bruce Poppe (797)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Catherine M. Phelan (219497)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christina Edwinsdotter Ardnor (3147171)
- Christopher R. Hake (3147183)
- Claude Houdayer (395237)
- Claudine Isaacs (59927)
- Csilla I. Szabo (395202)
- D. Gareth Evans (154186)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Vigorito (141461)
- Elizabeth J. van Rensburg (395205)
- Eric A. Ross (3147168)
- Esther M. John (107266)
- Evgeny N. Imyanitov (395207)
- Fabienne Lesueur (10534)
- Fergus J. Couch (146607)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Grzegorz Sukiennicki (196615)
- Gustavo C. Rodriguez (395256)
- Heli Nevanlinna (83762)
- Ian Campbell (205212)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Jonathan Beesley (89897)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Judy Kirk (15511)
- Julian Adlard (395223)
- Kai-ren Ong (3147165)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen B. M. Claes (3147162)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Laima Tihomirova (196713)
- Laure Barjhoux (395412)
- Lauren Jacobs (484900)
- Lesley McGuffog (153865)
- Lidia Feliubadalo (3147198)
- Liliana Varesco (381200)
- Louise Izatt (69449)
- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Martine Dumont (553712)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Miquel Angel Pujana (395274)
- Muriel Belotti (395413)
- Muy-Kheng Tea (308359)
- Noralane Lindor (154074)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Patricia A. Ganz (395212)
- Paul D. P. Pharoah (146906)
- Penny Soucy (21792)
- Peter J. Hulick (3147177)
- Phuong L. Mai (238716)
- Pragna Gaddam (759099)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Ros Eeles (238725)
- Rosemarie Davidson (154164)
- Salina B. Chan (395287)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Sofia Khan (79890)
- Soo-Hwang Teo (266270)
- Sophie Giraud (3147180)
- Steve Ellis (395221)
- Sue Healey (41187)
- Sue Kyung Park (549838)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Sylvie Mazoyer (196744)
- Thomas P. Slavin (3147186)
- Thomas V. O. Hansen (395201)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vanesa Garcia-Barberan (3147174)
- William D. Foulkes (232312)
- Yael Laitman (196595)
- Ylva Paulsson-Karlsson (3147189)
- Publication venue
- Publication date
- Field of study
<p>Illustration of the genomic region (chr9:16,839,835–16,924,468) encompassing peaks (shaded areas) containing candidate causal variants associated with ovarian cancer risk in <i>BRCA1</i> and <i>BRCA2</i> mutation carriers. Epigenomic data from Coetzee et al., (2015) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0158801#pone.0158801.ref020" target="_blank">20</a>] representing potential regulatory elements in ovarian cells (iOSE4 and iOSE11) and fallopian tube (FTSEC33) cells derived from formaldehyde assisted identification of regulatory elements sequencing (FAIRE-seq) and histone modification ChIP-seq are shown as black bars. Variants which overlap one of these features are coloured red. Data from the ENCODE project including histone modification ChIP-seq for three modifications (H3K4me1, H3K4me3, and H3K27ac) are shown as coloured histograms, as well as DNaseI hypersensitive site mapping and transcription factor ChIP-seq. The positions of all common SNPs from dbSNP build 142 are shown in the lowest track.</p
Associations between SNPs in 9p22.2 with ovarian cancer risk for the meta-analysis of <i>BRCA1</i> and <i>BRCA2</i> mutation carriers.
- Author
- Alfons Meindl (112058)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Angel Izquierdo (3147192)
- Anna Jakubowska (146752)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Antoine de Pauw (196753)
- Antonis C. Antoniou (146788)
- Arjen R. Mensenkamp (2271544)
- Athanassios Vratimos (3147159)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Bruce Poppe (797)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Catherine M. Phelan (219497)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christina Edwinsdotter Ardnor (3147171)
- Christopher R. Hake (3147183)
- Claude Houdayer (395237)
- Claudine Isaacs (59927)
- Csilla I. Szabo (395202)
- D. Gareth Evans (154186)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Vigorito (141461)
- Elizabeth J. van Rensburg (395205)
- Eric A. Ross (3147168)
- Esther M. John (107266)
- Evgeny N. Imyanitov (395207)
- Fabienne Lesueur (10534)
- Fergus J. Couch (146607)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Grzegorz Sukiennicki (196615)
- Gustavo C. Rodriguez (395256)
- Heli Nevanlinna (83762)
- Ian Campbell (205212)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Jonathan Beesley (89897)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Judy Kirk (15511)
- Julian Adlard (395223)
- Kai-ren Ong (3147165)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen B. M. Claes (3147162)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Laima Tihomirova (196713)
- Laure Barjhoux (395412)
- Lauren Jacobs (484900)
- Lesley McGuffog (153865)
- Lidia Feliubadalo (3147198)
- Liliana Varesco (381200)
- Louise Izatt (69449)
- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Martine Dumont (553712)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Miquel Angel Pujana (395274)
- Muriel Belotti (395413)
- Muy-Kheng Tea (308359)
- Noralane Lindor (154074)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Patricia A. Ganz (395212)
- Paul D. P. Pharoah (146906)
- Penny Soucy (21792)
- Peter J. Hulick (3147177)
- Phuong L. Mai (238716)
- Pragna Gaddam (759099)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Ros Eeles (238725)
- Rosemarie Davidson (154164)
- Salina B. Chan (395287)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Sofia Khan (79890)
- Soo-Hwang Teo (266270)
- Sophie Giraud (3147180)
- Steve Ellis (395221)
- Sue Healey (41187)
- Sue Kyung Park (549838)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Sylvie Mazoyer (196744)
- Thomas P. Slavin (3147186)
- Thomas V. O. Hansen (395201)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vanesa Garcia-Barberan (3147174)
- William D. Foulkes (232312)
- Yael Laitman (196595)
- Ylva Paulsson-Karlsson (3147189)
- Publication venue
- Publication date
- Field of study
<p>(A) The purple diamond corresponds to the strongest associated SNP and the colour code indicates the linkage disequilibrium with respect to this variant. Horizontal lines indicate the -log<sub>10</sub> p-value such that the SNPs above the line are the potential causal ones. This set was defined based on a likelihood ratio for a particular SNP as being less or equal than 100, relative to the most likely variant and r<sup>2</sup>>0.1. (B) Haplotype block indicating relevant SNPs. From left to right the indicated SNPs correspond to: the strongest associated in <i>BRCA1/2</i> meta-analysis, the strongest in <i>BRCA1</i> and the strongest in <i>BRCA2</i>.</p
Conditional associations for <i>BRCA1</i> and <i>BRCA2</i> top SNPs.
- Author
- Alfons Meindl (112058)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Angel Izquierdo (3147192)
- Anna Jakubowska (146752)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Antoine de Pauw (196753)
- Antonis C. Antoniou (146788)
- Arjen R. Mensenkamp (2271544)
- Athanassios Vratimos (3147159)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Bruce Poppe (797)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Catherine M. Phelan (219497)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christina Edwinsdotter Ardnor (3147171)
- Christopher R. Hake (3147183)
- Claude Houdayer (395237)
- Claudine Isaacs (59927)
- Csilla I. Szabo (395202)
- D. Gareth Evans (154186)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Vigorito (141461)
- Elizabeth J. van Rensburg (395205)
- Eric A. Ross (3147168)
- Esther M. John (107266)
- Evgeny N. Imyanitov (395207)
- Fabienne Lesueur (10534)
- Fergus J. Couch (146607)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Grzegorz Sukiennicki (196615)
- Gustavo C. Rodriguez (395256)
- Heli Nevanlinna (83762)
- Ian Campbell (205212)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Jonathan Beesley (89897)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Judy Kirk (15511)
- Julian Adlard (395223)
- Kai-ren Ong (3147165)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen B. M. Claes (3147162)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Laima Tihomirova (196713)
- Laure Barjhoux (395412)
- Lauren Jacobs (484900)
- Lesley McGuffog (153865)
- Lidia Feliubadalo (3147198)
- Liliana Varesco (381200)
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- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Martine Dumont (553712)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Miquel Angel Pujana (395274)
- Muriel Belotti (395413)
- Muy-Kheng Tea (308359)
- Noralane Lindor (154074)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
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- Paul D. P. Pharoah (146906)
- Penny Soucy (21792)
- Peter J. Hulick (3147177)
- Phuong L. Mai (238716)
- Pragna Gaddam (759099)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Ros Eeles (238725)
- Rosemarie Davidson (154164)
- Salina B. Chan (395287)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Sofia Khan (79890)
- Soo-Hwang Teo (266270)
- Sophie Giraud (3147180)
- Steve Ellis (395221)
- Sue Healey (41187)
- Sue Kyung Park (549838)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Sylvie Mazoyer (196744)
- Thomas P. Slavin (3147186)
- Thomas V. O. Hansen (395201)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vanesa Garcia-Barberan (3147174)
- William D. Foulkes (232312)
- Yael Laitman (196595)
- Ylva Paulsson-Karlsson (3147189)
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<p><b>The table shows the HR estimate. 95% CI and p-value for the conditional analysis adjusting for the lead SNP in the univariate analysis for <i>BRCA1</i> (left hand side) or <i>BRCA2</i> mutation carriers (right had side).</b> SNPs correspond to: rs10124837, the strongest associated in <i>BRCA1</i>; rs62543583, the strongest associated in <i>BRCA2</i> mutation carriers; rs7046326, the strongest associated in <i>BRCA1/2</i> meta-analysis; rs3814113, was the strongest associated variant in the initial GWAS analysis. “HR”, hazard ratio; “CI”, confidence interval.</p
[unknown]
- Author
- Adalgeir Arason (238680)
- Adam Freeman (3437756)
- Alex TeulĂŠ (3437813)
- Alfons Meindl (112058)
- Alice Sigurdson (89952)
- Alice Whittemore (3437711)
- Alicia Beeghly-Fadiel (732867)
- Alison Dunning (10539)
- Amanda Toland (3405350)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew Godwin (811543)
- Angela Cox (76913)
- Anja Rudolph (180618)
- Anna GonzĂĄlez-Neira (3437816)
- Anna Jakubowska (146752)
- Anna Mulligan (3437741)
- Anna Wu (3412982)
- Anne-Lise Borresen-Dale (2697364)
- Annegien Broeks (146385)
- Annelie Liljegren (716112)
- Annika Lindblom (26099)
- Ans van den Ouweland (89937)
- Anthony Swerdlow (146780)
- Antoinette Hollestelle (52748)
- Antonis Antoniou (3405323)
- Arnaud Droit (36418)
- Artitaya Lophatananon (146409)
- Arto Mannermaa (89891)
- Ava Kwong (52115)
- Banu Arun (3405263)
- Barbara Burwinkel (146479)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernd Dworniczak (223446)
- Beth Karlan (233752)
- Brita Arver (395252)
- Carl Blomqvist (83761)
- Caroline Baynes (73973)
- Caroline Seynaeve (95368)
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- Cecilia Dorfling (3437753)
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- Christine Clarke (3437759)
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- Chuen Lee (3437720)
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- Claudine Isaacs (59927)
- Conxi Lazaro (3405329)
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- Daehee Kang (6451)
- Daniel Barrowdale (395192)
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- David Hunter (273536)
- David ven den Berg (3074547)
- Debra Frost (154160)
- Diether Lambrechts (101772)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas Easton (25461)
- Drakoulis Yannoukakos (4758)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elinor Sawyer (146459)
- Elizabeth van Rensburg (3405299)
- Elza Khusnutdinova (146583)
- Emily Hallberg (553716)
- Esther John (413149)
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- Gad Rennert (196538)
- Gaetana Gambino (3437747)
- Georg Pfeiler (395261)
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- Hermann Brenner (63649)
- Hidemi Ito (181434)
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原著和名: [記載なし]科名: = unknown採集地: タイ カオヤイ国立公園 (タイ国 カオヤイ国立公園)採集日: 1984/10/13採集者: 萩庭丈壽整理番号: JH051286国立科学博物館整理番号: TNS-VS-94871