Longitudinal differences of ionospheric vertical density distribution and equatorial electrodynamics

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95627/1/jgra21851.pd

The occurrence of ionospheric signatures of plasmaspheric plumes over different longitudinal sectors

Plasmaspheric plumes have ionospheric signatures and are observed as storm-enhanced density (SED) in global positioning system (GPS) total electron content (TEC). These ionospheric signatures have been primarily observed over the American sector and in a few limited examples over the European sector. This study examines the longitudinal occurrence frequency of plasmaspheric plumes. We analyzed all images from the Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) Extreme Ultraviolet Imager (EUV) databases for the first half of 2001 and identified a total of 31 distinct plume intervals observed during different storm events. Out of the total IMAGE EUV plumes that we identified, 12 were projected over North America, 10 over Asia, and the remaining 9 were over Europe and the Atlantic Ocean. Using ground-based GPS TEC from MIT\u27s Madrigal database, we searched for corresponding SED/TEC plumes at different longitudinal sector and found 12 ionospheric SED plume signatures over North America, 4 over Europe, and 2 over Asia. This indicates that the observation probability of an ionospheric SED plume when a plasmaspheric plume is seen is 100% in the American sector, 50% in the European sector, and 20% in the Asian sector. This could be due to the fact that the plumes may be either positioned beyond the limit of the ground-based GPS field of view, which happens mainly when there is less plasmaspheric erosion, or are too weak to be detected by the sparse number of GPS receivers over Asia. The in situ plasma densities from the available coincident defense metrological satellite program (DMSP) satellites were also used to study the characteristics of SED/TEC plume at DMSP orbiting altitude (i.e., ∼870 km). The TOPographic EXplorer (TOPEX) altimeter TEC also is used to identify the conjugate SED/plume signature over the Southern Hemisphere

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions

Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication. Neutrophils are highly versatile cells, which play a crucial role in the induction as well as the resolution of inflammation, the control of pathogen replication and the regulation of immune responses. Neutrophil functions have been investigated in human cutaneous leishmaniasis, however, their role in human visceral leishmaniasis is poorly understood. In the present study we evaluated the activation status and effector functions of neutrophils in patients with active VL and after successful anti-leishmanial treatment. Our results show that neutrophils are highly activated and have degranulated; high levels of arginase, myeloperoxidase and elastase, all contained in neutrophils’ granules, were found in the plasma of VL patients. In addition, we show that a large proportion of these cells are immature. We also analysed effector functions of neutrophils that are essential for pathogen clearance and show that neutrophils have an impaired capacity to release neutrophil extracellular traps, produce reactive oxygen species and phagocytose bacterial particles, but not Leishmania parasites. Our results suggest that impaired effector functions, increased activation and immaturity of neutrophils play a key role in the pathogenesis of VL

The longitudinal variability of equatorial electrojet and vertical drift velocity in the African and American sectors

While the formation of equatorial electrojet (EEJ) and its temporal variation is believed to be fairly well understood, the longitudinal variability at all local times is still unknown. This paper presents a case and statistical study of the longitudinal variability of dayside EEJ for all local times using ground-based observations. We found EEJ is stronger in the west American sector and decreases from west to east longitudinal sectors. We also confirm the presence of significant longitudinal difference in the dusk sector pre-reversal drift, using the ion velocity meter (IVM) instrument onboard the C/NOFS satellite, with stronger pre-reversal drift in the west American sector compared to the African sector. Previous satellite observations have shown that the African sector is home to stronger and year-round ionospheric bubbles/irregularities compared to the American and Asian sectors. This study's results raises the question if the vertical drift, which is believed to be the main cause for the enhancement of Rayleigh–Taylor (RT) instability growth rate, is stronger in the American sector and weaker in the African sector – why are the occurrence and amplitude of equatorial irregularities stronger in the African sector

Response of the equatorial ionosphere to the geomagnetic DP 2 current system

The response of equatorial ionosphere to the magnetospheric origin DP 2 current system fluctuations is examined using ground‐based multiinstrument observations. The interaction between the solar wind and magnetosphere generates a convection electric field that can penetrate to the ionosphere and cause the DP 2 current system. The quasiperiodic DP 2 current system, which fluctuates coherently with fluctuations of the interplanetary magnetic field (IMF) Bz, penetrates nearly instantaneously to the dayside equatorial region at all longitudes and modulates the electrodynamics that governs the equatorial density distributions. In this paper, using magnetometers at high and equatorial latitudes, we demonstrate that the quasiperiodic DP 2 current system penetrates to the equator and causes the dayside equatorial electrojet (EEJ) and the independently measured ionospheric drift velocity to fluctuate coherently with the high‐latitude DP 2 current as well as with the IMF Bz component. At the same time, radar observations show that the ionospheric density layers move up and down, causing the density to fluctuate up and down coherently with the EEJ and IMF Bz.Key PointsThe solar wind‐magnetosphere interaction generates DP 2 current fluctuationThe DP 2 current fluctuations penetrate to the equator and cause the equatorial electrodynamics to fluctuateIt also causes the equatorial density to fluctuate which might affect the communication and navigation systemsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134255/1/grl54722.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134255/2/grl54722_am.pd

ULF Wave‐Associated Density Irregularities and Scintillation at the Equator

This paper presents independent multi‐instrument observations that address the physical mechanisms of how ultralow‐frequency (ULF) wave‐associated electric fields initiate ionospheric density fluctuation and scintillation at the equator. Since the magnetic field at the equator is entirely embedded in a relatively high‐collision and high‐conductivity medium, the condition may not be possible for the geomagnetic field to fluctuate due to ULF wave activity. This implies that the fluctuating electric field at the equator may not be produced through equatorial dynamo action due to fluctuating magnetic fields. Instead, the electric field penetrates from high latitudes and produces fluctuating magnetic field as well as modulates the vertical drift and hence causes the density to fluctuate at the equatorial region. We demonstrate this by estimating the ULF associated fluctuating electric field at high latitudes and at the equatorial region by applying the appropriate attenuation factor as it penetrates to lower latitudes. The periodicity of both electric field and density fluctuations appears to be between 6 and 9 min, which is a typical period of ULF waves in the Pc5 range. Because of its large amplitude and long periods compared to other ULF wave frequency bands, the Pc5 wave‐associated electric field, which can even be estimated using magnetograms with low sensitivity and low sampling rate (e.g., 1 min), can easily penetrate to the lower latitude region and produce significant ionospheric density fluctuations that can be strong enough to create scintillation at the equatorial region.Plain Language SummaryThe ultralow‐frequency (ULF) wave, which is believed to be generated by strong solar wind dynamic pressure at the magnetopause, can penetrate to the ionosphere and modulate high‐latitude electric field that can penetrate to equatorial latitudes and cause density irregularities in the ionosphere. Especially in the dusk to midnight local time sector, when the background density is weaker and can easily be driven up and down by small magnitude of fluctuating electric field (vertical drift), the density fluctuation becomes stronger. Such density fluctuations create favorable conditions for the creation of rapid amplitude and phase fluctuations of radio signals, which affects several technological systems such as over the horizon high‐frequency radio communication outage and increased Global Navigation Satellite System navigation errors. Thus, ionospheric density fluctuations are as much an engineering concern as they are a scientific quest, and hence understanding the physics behind the contribution of ULF wave power for the formation of small‐scale ionospheric density fluctuations is very important to develop a model that can accurately capture the structure and dynamics of the global low‐latitude ionospheric irregularities.Key PointsULF modulates high-latitude electric fieldElectric field penetrates from high to low latitudesFluctuating electric field causes scintillation at the equatorPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144582/1/grl57466.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144582/2/grl57466_am.pd