Non-Ischemic, Non-Hypoxic Myocardial Injury, and Long-Term Mortality in Patients with Coronavirus Disease 2019: A Retrospective Cohort Study.

Cardiac damage is commonly reported in patients with coronavirus disease 2019 (COVID-19) but its prevalence and impact on the long-term survival of patients remain uncertain. This study aimed to explore the prevalence of myocardial injury and assess its prognostic value in patients with COVID-19. A single-center, retrospective cohort study was performed at the Affiliated Hospital of Jianghan University. Data from 766 patients with confirmed COVID-19 who were hospitalized from December 27, 2019 to April 25, 2020 were collected. Demographic, clinical, laboratory, electrocardiogram, treatment data and all-cause mortality during follow-up were collected and analyzed. Of the 766 patients with moderate to critically ill COVID-19, 86 (11.2%) died after a mean follow-up of 72.8 days. Myocardial injury occurred in 94 (12.3%) patients. The mortality rate was 64.9% (61/94) and 3.7% (25/672) in patients with and without myocardial injury, respectively. Cox regression showed that myocardial injury was an independent risk factor for mortality (hazard ratio: 8.76, 95% confidence interval: 4.76-16.11,    0.001). Of the 90 patients with myocardial injury with electrocardiogram results, sinus tachycardia was present in 29, bundle branch block in 26, low voltage in 10, and abnormal T-wave in 53. COVID-19 not only involves pneumonia but also cardiac damage. Myocardial injury is a common complication and an independent risk factor for mortality in COVID-19 patients

Vaccination against coronavirus disease 2019 in patients with pulmonary hypertension: a national prospective cohort study

Background: Coronavirus disease 2019 (COVID-19) has potential risks for both clinically worsening pulmonary hypertension (PH) and increasing mortality. However, the data regarding the protective role of vaccination in this population are still lacking. This study aimed to assess the safety of approved vaccination for patients with PH. Methods: In this national prospective cohort study, patients diagnosed with PH (World Health Organization [WHO] groups 1 and 4) were enrolled from October 2021 to April 2022. The primary outcome was the composite of PH-related major adverse events. We used an inverse probability weighting (IPW) approach to control for possible confounding factors in the baseline characteristics of patients. Results: In total, 706 patients with PH participated in this study (mean age, 40.3 years; mean duration after diagnosis of PH, 8.2 years). All patients received standardized treatment for PH in accordance with guidelines for the diagnosis and treatment of PH in China. Among them, 278 patients did not receive vaccination, whereas 428 patients completed the vaccination series. None of the participants were infected with COVID-19 during our study period. Overall, 398 patients received inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, whereas 30 received recombinant protein subunit vaccine. After adjusting for baseline covariates using the IPW approach, the odds of any adverse events due to PH in the vaccinated group did not statistically significantly increase (27/428 [6.3%] vs. 24/278 [8.6%], odds ratio = 0.72, P = 0.302). Approximately half of the vaccinated patients reported at least one post-vaccination side effects, most of which were mild, including pain at the injection site (159/428, 37.1%), fever (11/428, 2.6%), and fatigue (26/428, 6.1%). Conclusions: COVID-19 vaccination did not significantly augment the PH-related major adverse events for patients with WHO groups 1 and 4 PH, although there were some tolerable side effects. A large-scale randomized controlled trial is warranted to confirm this finding. The final approval of the COVID-19 vaccination for patients with PH as a public health strategy is promising

Molecular identification and phylogenetic analysis of mitogenome of the Xenocypris davidi from Cao’e River

In this study, the complete mitochondrial genome sequence of a Xenocypris davidi from Cao’e River was sequenced. The complete mitogenome of X. davidi was 16,630 bp in length, it contains the structure of 22 transfer RNA genes, 13 protein coding genes, 2 ribosomal RNA genes, and 1 non-coding region. The gene arrangement and organization in the mitogenome of X. davidi were in accordance with other Cyprinidae fishes. The results of phylogenetic analysis revealed that the mitochondrial genome sequence could provide useful information for the conservation genetics and evolution study of X. davidi

Seepage Characteristics and Influencing Factors of Weakly Consolidated Rocks in Triaxial Compression Test under Mining-Induced Stress Path

The rock of weakly consolidated coal measure strata has the characteristics of low mechanical strength and strong water sensitivity. Under the stress and seepage disturbance caused by coal seam mining, the surrounding rock structure is prone to instability, which leads to mine safety accidents and water resources loss. In order to master the mechanical response and permeability evolution law of weakly consolidated rock under the disturbance of coal seam mining, the specimens of Jurassic mudstone, sandy mudstone, and sandstone in the Ili mining area of China were collected, and a triaxial compression seepage test was carried out. A comprehensive analysis was carried out on the mineral composition and microstructure characteristics of the rock. The results show the following: (1) Compared to the constant confining pressure condition, mining-induced stress promotes the fracture development rate of weakly consolidated rocks. The ratios of strain at the yield point of mudstone, sandy mudstone, and sandstone under mining-induced stress and constant confining pressure are 0.33, 0.43, and 0.79, respectively, and the ratios of strain at the failure point were 0.48, 0.52, and 0.72, respectively. (2) Under the condition of mining-induced stress, the permeability change range and the permeability recovery rate of the three types of rocks were different, which decreased in the order of mudstone, sandy mudstone, and sandstone. (3) In the process of the triaxial compression test, there was a strong hysteresis in the permeability change of the mudstone, and the permeability and hysteresis of the three types of rocks decreased with the increase in the clay mineral content. (4) Combined with the analysis of the rock mineral composition and microstructure characteristics, it is believed that the clay minerals in the rock after water mud and swelling are the main reasons for the hysteresis of the permeability change of weakly consolidated rock, and the content of clay minerals is the main factor affecting the permeability characteristics of the weakly consolidated rock

Seepage Characteristics and Influencing Factors of Weakly Consolidated Rocks in Triaxial Compression Test under Mining-Induced Stress Path

The rock of weakly consolidated coal measure strata has the characteristics of low mechanical strength and strong water sensitivity. Under the stress and seepage disturbance caused by coal seam mining, the surrounding rock structure is prone to instability, which leads to mine safety accidents and water resources loss. In order to master the mechanical response and permeability evolution law of weakly consolidated rock under the disturbance of coal seam mining, the specimens of Jurassic mudstone, sandy mudstone, and sandstone in the Ili mining area of China were collected, and a triaxial compression seepage test was carried out. A comprehensive analysis was carried out on the mineral composition and microstructure characteristics of the rock. The results show the following: (1) Compared to the constant confining pressure condition, mining-induced stress promotes the fracture development rate of weakly consolidated rocks. The ratios of strain at the yield point of mudstone, sandy mudstone, and sandstone under mining-induced stress and constant confining pressure are 0.33, 0.43, and 0.79, respectively, and the ratios of strain at the failure point were 0.48, 0.52, and 0.72, respectively. (2) Under the condition of mining-induced stress, the permeability change range and the permeability recovery rate of the three types of rocks were different, which decreased in the order of mudstone, sandy mudstone, and sandstone. (3) In the process of the triaxial compression test, there was a strong hysteresis in the permeability change of the mudstone, and the permeability and hysteresis of the three types of rocks decreased with the increase in the clay mineral content. (4) Combined with the analysis of the rock mineral composition and microstructure characteristics, it is believed that the clay minerals in the rock after water mud and swelling are the main reasons for the hysteresis of the permeability change of weakly consolidated rock, and the content of clay minerals is the main factor affecting the permeability characteristics of the weakly consolidated rock

Possible contribution of endogenous carbon monoxide to the development of allergic rhinitis in guinea pigs

BACKGROUND: The mechanisms responsible for the development of allergic rhinitis(AR) are not fully understood. The present study was designed to explore the possible roles of carbon monoxide(CO) on the pathogenesis of AR. METHODS: AR guinea pig model was established by nasal ovalbumin sensitization. Twenty-four AR guinea pigs were divided into four groups, 6 in each: Saline control group, AR sensitized group, Hemin treated group, and Zinc protoporphyrin (ZnPP) treated group. The frequency of sneezing and nose rubbing was recorded. Leukocyte infiltration in nasal lavage fluid, serum IgE level and plasma CO were measured. Expression of heme oxygenase-1 (HO-1) mRNA in nasal mucosa was determined by real time RT-PCR, and expression of HO-1 protein was detected by immunohistochemistry. RESULTS: The frequency of sneezing and nose rubbing, leukocyte infiltration, serum IgE, plasma CO, and HO-1 mRNA levels in sensitized guinea pigs were higher than those of control (P < 0.05). Except for serum IgE level, all above parameters were even higher (P < 0.05) when treated with Hemin, a heme oxygenase-1 inducer; but significantly decreased (P < 0.05) when treated with ZnPP, a heme oxygenase inhibitor. Immunohistochemical results showed that positive staining of HO-1 was present in the lamina of mucosa of sensitized guinea pigs, and there was an increase of HO-1 immunoreactivity with Hemin administration (P < 0.05) and a decrease with ZnPP treatment. CONCLUSION: The endogenous CO may take part in the inflammation process of AR and is positively correlated with expression of HO-1 in nasal mucosa. Endogenous CO plays a significant role in the pathogenesis of AR

Possible contribution of endogenous carbon monoxide to the development of allergic rhinitis in guinea pigs

Abstract Background The mechanisms responsible for the development of allergic rhinitis(AR) are not fully understood. The present study was designed to explore the possible roles of carbon monoxide(CO) on the pathogenesis of AR. Methods AR guinea pig model was established by nasal ovalbumin sensitization. Twenty-four AR guinea pigs were divided into four groups, 6 in each: Saline control group, AR sensitized group, Hemin treated group, and Zinc protoporphyrin (ZnPP) treated group. The frequency of sneezing and nose rubbing was recorded. Leukocyte infiltration in nasal lavage fluid, serum IgE level and plasma CO were measured. Expression of heme oxygenase-1 (HO-1) mRNA in nasal mucosa was determined by real time RT-PCR, and expression of HO-1 protein was detected by immunohistochemistry. Results The frequency of sneezing and nose rubbing, leukocyte infiltration, serum IgE, plasma CO, and HO-1 mRNA levels in sensitized guinea pigs were higher than those of control (P Conclusion The endogenous CO may take part in the inflammation process of AR and is positively correlated with expression of HO-1 in nasal mucosa. Endogenous CO plays a significant role in the pathogenesis of AR.</p

ECP-WarpX/WarpX: 24.01

&lt;h1&gt;Dependencies&lt;/h1&gt; &lt;ul&gt; &lt;li&gt;&lt;a href="https://github.com/AMReX-Codes/amrex/tree/24.01"&gt;AMReX&lt;/a&gt;: &lt;code&gt;24.01&lt;/code&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/ECP-WarpX/picsar/tree/23.09"&gt;PICSAR&lt;/a&gt;-QED: &lt;code&gt;23.09&lt;/code&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/picmi-standard/picmi"&gt;picmistandard&lt;/a&gt;: release &lt;code&gt;0.28.0&lt;/code&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/openPMD/openPMD-api"&gt;openPMD-api&lt;/a&gt;: release &lt;code&gt;0.15.1&lt;/code&gt;&lt;/li&gt; &lt;li&gt;Python: 3.8 - 3.12&lt;/li&gt; &lt;/ul&gt; &lt;h1&gt;List of PRs merged since the last release&lt;/h1&gt; &lt;p&gt;This list was generated with&lt;/p&gt; &lt;pre&gt;&lt;code&gt;git log 23.12.. --format='- %s' &lt;/code&gt;&lt;/pre&gt; &lt;ul&gt; &lt;li&gt;Release 24.01 (#4586)&lt;/li&gt; &lt;li&gt;Read external fields from file in restarted simulation (#4547)&lt;/li&gt; &lt;li&gt;Doc: Clean Example TODOs (#4584)&lt;/li&gt; &lt;li&gt;Reduce tolerance for DSMC CI test (#4576)&lt;/li&gt; &lt;li&gt;Beam-beam collision example follow-up (#4578)&lt;/li&gt; &lt;li&gt;Scale fields by a dimensionless number between 0 and 1 (#4575)&lt;/li&gt; &lt;li&gt;Perlmutter: Load &lt;code&gt;gpu&lt;/code&gt; Module (#4573)&lt;/li&gt; &lt;li&gt;Beam-beam collision example (#4546)&lt;/li&gt; &lt;li&gt;Update dsmc and fusion binary collisions (#4572)&lt;/li&gt; &lt;li&gt;Apply particle selection to BTDiagnostics (#4570)&lt;/li&gt; &lt;li&gt;Update the field probe diagnostic documentation (#4564)&lt;/li&gt; &lt;li&gt;Add filters for boundary scraping diagnostics (#4371)&lt;/li&gt; &lt;li&gt;Add semi-implicit CI test (#4565)&lt;/li&gt; &lt;li&gt;Change the sign of laser particles (#4568)&lt;/li&gt; &lt;li&gt;Update explanation of why 2D simulations are not suitable for plasma-wakefield (#4544)&lt;/li&gt; &lt;li&gt;Fix default initialization of runtime attributes. (#4508)&lt;/li&gt; &lt;li&gt;Implicit electromagnetic solver using Picard iterations (#4071)&lt;/li&gt; &lt;li&gt;Update documentation for checksum (#4561)&lt;/li&gt; &lt;li&gt;Fix: BeamRelevant 1D, 2D (#4558)&lt;/li&gt; &lt;li&gt;Add DSMC module (#4125)&lt;/li&gt; &lt;li&gt;Add updated instructions for WarpX on Karolina (#4545)&lt;/li&gt; &lt;li&gt;AMReX/pyAMReX/PICSAR: Weekly Update (#4559)&lt;/li&gt; &lt;li&gt;Fix reference (#4552)&lt;/li&gt; &lt;li&gt;add hybrid-PIC PoP reference to docs (#4551)&lt;/li&gt; &lt;li&gt;Clean up doc to improve readability (#4555)&lt;/li&gt; &lt;li&gt;Adding user defined keywords in Hybrid PIC Python class to allow for addition of constants when defining functions for resistivity and current. (#4550)&lt;/li&gt; &lt;li&gt;WarpXAMReXInit: move include directive from header to cpp file (#4543)&lt;/li&gt; &lt;li&gt;AMReX/pyAMReX/PICSAR: Weekly Update (#4541)&lt;/li&gt; &lt;li&gt;[pre-commit.ci] pre-commit autoupdate (#4539)&lt;/li&gt; &lt;li&gt;Add updated instructions for WarpX on Karolina (#4477)&lt;/li&gt; &lt;li&gt;Doc: CUDA 11.7+ (#4538)&lt;/li&gt; &lt;li&gt;Spruce up kinetic_fluid_hybrid_model.rst (#4534)&lt;/li&gt; &lt;li&gt;Docs: rename and spruce up boundary conditions section (#4537)&lt;/li&gt; &lt;li&gt;Spruce up PIC theory section (#4536)&lt;/li&gt; &lt;li&gt;Spruce up ml_dataset_training.rst (#4512)&lt;/li&gt; &lt;li&gt;Fix CI for ROCm 6.0 (#4527)&lt;/li&gt; &lt;li&gt;Documentation: numbered reference formatting (#4528)&lt;/li&gt; &lt;li&gt;Spruce up boosted_frame.rst (#4530)&lt;/li&gt; &lt;li&gt;Spruce up cold_fluid_model.rst (#4531)&lt;/li&gt; &lt;li&gt;Spruce up input_output.rst (#4532)&lt;/li&gt; &lt;li&gt;Fix chirp documentation (#4533)&lt;/li&gt; &lt;li&gt;Doc: Extend a Simulation Workflow (#4520)&lt;/li&gt; &lt;li&gt;Spruce up amr.rst (#4529)&lt;/li&gt; &lt;li&gt;WarpXSumGuardCells: move function definitions in cpp file (#4521)&lt;/li&gt; &lt;li&gt;Doc: Fix ChecksumAPI &lt;code&gt;autofunction&lt;/code&gt; (#4524)&lt;/li&gt; &lt;li&gt;Improve documentation for laser chirp (#4525)&lt;/li&gt; &lt;li&gt;move function definition to cpp file (#4522)&lt;/li&gt; &lt;li&gt;Add ability to run checksum on openPMD files (#4519)&lt;/li&gt; &lt;li&gt;Clang-Tidy: readability-qualified-auto (#4507)&lt;/li&gt; &lt;li&gt;Clang-Tidy: performance-noexcept-move-constructor (#4504)&lt;/li&gt; &lt;li&gt;Bibliography: make author family names appear last (#4506)&lt;/li&gt; &lt;li&gt;Doc: Examples Before APIs&lt;/li&gt; &lt;li&gt;Doc: Fix Sphinx Warnings&lt;/li&gt; &lt;li&gt;Bibliography: improved citations (#4513)&lt;/li&gt; &lt;li&gt;Update descriptions of hybrid-PIC examples (#4479)&lt;/li&gt; &lt;li&gt;Clang-tidy: enable no-malloc check in clang-tidy CI test (#4518)&lt;/li&gt; &lt;li&gt;Clang-Tidy: readability-inconsistent-declaration-parameter-name (#4514)&lt;/li&gt; &lt;li&gt;Clang-Tidy: readability-braces-around-statements (#4511)&lt;/li&gt; &lt;li&gt;workflow training neural network from warpx data (#4499)&lt;/li&gt; &lt;li&gt;AMReX/pyAMReX/PICSAR: Weekly Update (#4503)&lt;/li&gt; &lt;li&gt;Use more consistent species types in fusion module (#4480)&lt;/li&gt; &lt;li&gt;Clang-tidy: enable readability-duplicate-include check in clang-tidy CI test (#4496)&lt;/li&gt; &lt;li&gt;AMReX/pyAMReX/PICSAR: Weekly Update (#4489)&lt;/li&gt; &lt;li&gt;Custom class for bibliography style (#4482)&lt;/li&gt; &lt;li&gt;[pre-commit.ci] pre-commit autoupdate (#4500)&lt;/li&gt; &lt;li&gt;Move external field parameters out of WarpX class (#4441)&lt;/li&gt; &lt;li&gt;Tidy-Clang: performance-type-promotion-in-math-fn (#4497)&lt;/li&gt; &lt;li&gt;Clang-Tidy CI: Keep Going after Errors (#4491)&lt;/li&gt; &lt;li&gt;Clang-Tidy: Update performance and readability (#4492)&lt;/li&gt; &lt;li&gt;sqrt -&gt; std::sqrt (#4490)&lt;/li&gt; &lt;li&gt;macOS CI: Fix brew installation (#4493)&lt;/li&gt; &lt;li&gt;Add &lt;code&gt;latex_theory/allbibs.bib&lt;/code&gt; to bibliography list and delete duplicates (#4481)&lt;/li&gt; &lt;li&gt;Set alpha mass directly from NIST data (#4478)&lt;/li&gt; &lt;li&gt;pybind11: v2.11.1+ (#4473)&lt;/li&gt; &lt;li&gt;Fix typos in comments and docs (#4471)&lt;/li&gt; &lt;li&gt;Correct on-axis field boundary for RZ (#4464)&lt;/li&gt; &lt;li&gt;Rename Depose -&gt; Deposit (#4474)&lt;/li&gt; &lt;li&gt;Doc: Streamline Python Input (#4472)&lt;/li&gt; &lt;li&gt;macOS CI: export CCACHE_DEPEND=1 (#4475)&lt;/li&gt; &lt;li&gt;Docs: Fix Formatting in &lt;code&gt;parameters.rst&lt;/code&gt;&lt;/li&gt; &lt;li&gt;Docs: Fix Many Small Errors &amp; Warnings&lt;/li&gt; &lt;li&gt;Doc: Restructure Examples (#4467)&lt;/li&gt; &lt;li&gt;Remove brew cache (#4470)&lt;/li&gt; &lt;/ul&gt

ECP-WarpX/WarpX: 23.12

&lt;h1&gt;Dependencies&lt;/h1&gt; &lt;ul&gt; &lt;li&gt;&lt;a href="https://github.com/AMReX-Codes/amrex/tree/23.12"&gt;AMReX&lt;/a&gt;: &lt;code&gt;23.12&lt;/code&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/ECP-WarpX/picsar/tree/23.09"&gt;PICSAR&lt;/a&gt;-QED: &lt;code&gt;23.09&lt;/code&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/picmi-standard/picmi"&gt;picmistandard&lt;/a&gt;: release &lt;code&gt;0.28.0&lt;/code&gt;&lt;/li&gt; &lt;li&gt;&lt;a href="https://github.com/openPMD/openPMD-api"&gt;openPMD-api&lt;/a&gt;: release &lt;code&gt;0.15.1&lt;/code&gt;&lt;/li&gt; &lt;li&gt;Python: 3.8 - 3.12&lt;/li&gt; &lt;/ul&gt; &lt;h1&gt;List of PRs merged since the last release&lt;/h1&gt; &lt;p&gt;This list was generated with&lt;/p&gt; &lt;pre&gt;&lt;code class="language-sh"&gt;git log 23.11.. --format='- %s' &lt;/code&gt;&lt;/pre&gt; &lt;ul&gt; &lt;li&gt;Release 23.12 (#4469)&lt;/li&gt; &lt;li&gt;Add external current handling to Ohm's law solver (#4405)&lt;/li&gt; &lt;li&gt;fix preprocessor defs for 1D in two locations (#4465)&lt;/li&gt; &lt;li&gt;Bugfix in &lt;code&gt;fields.py&lt;/code&gt; &lt;code&gt;mesh()&lt;/code&gt; with ghost cells included (#4466)&lt;/li&gt; &lt;li&gt;Fix typo in &quot;write_diagnostics_on_restart&quot; (#4463)&lt;/li&gt; &lt;li&gt;Make geometry.dims abort message more user-friendly (#4459)&lt;/li&gt; &lt;li&gt;New Cache Strategy (#4456)&lt;/li&gt; &lt;li&gt;Initial commit (#4460)&lt;/li&gt; &lt;li&gt;Set &lt;code&gt;amrex.omp_threads = &quot;nosmt&quot;&lt;/code&gt; (#4393)&lt;/li&gt; &lt;li&gt;AMReX: Update to &lt;code&gt;development&lt;/code&gt; (#4455)&lt;/li&gt; &lt;li&gt;Clang-Tidy Cache (#4453)&lt;/li&gt; &lt;li&gt;Allow multiple injection sources per species (#4196)&lt;/li&gt; &lt;li&gt;Frontier (OLCF): cupy (#4247)&lt;/li&gt; &lt;li&gt;add start/end moving step (#4437)&lt;/li&gt; &lt;li&gt;Contributing style and conventions additions (#4452)&lt;/li&gt; &lt;li&gt;CPU CI: Always Serialize (#4451)&lt;/li&gt; &lt;li&gt;Maxlevel user option for external field initialization (#4326)&lt;/li&gt; &lt;li&gt;Doc: Fix Typo &lt;code&gt;&lt;probe&gt;.integrate = true&lt;/code&gt; (#4449)&lt;/li&gt; &lt;li&gt;CI: numprocs * numthreads &lt;= 2 (#4450)&lt;/li&gt; &lt;li&gt;AMReX/pyAMReX/PICSAR: Weekly Update (#4447)&lt;/li&gt; &lt;li&gt;Move AnyFFT.H and FFT wrappers into ablastr (#4005)&lt;/li&gt; &lt;li&gt;Clang tidy CI test: add almost all modernize-* checks (#4319)&lt;/li&gt; &lt;li&gt;Set the particle fields directly to the constant external fields (#4339)&lt;/li&gt; &lt;li&gt;fix minor bug in picmi &lt;code&gt;ParticleDiagnostic&lt;/code&gt; (#4442)&lt;/li&gt; &lt;li&gt;Make whitespace alignment more consistent (#4440)&lt;/li&gt; &lt;li&gt;Add gaussian_parse_momentum_function (#4400)&lt;/li&gt; &lt;li&gt;Make the static variable &quot;authors&quot; of the WarpX class a private member of the WarpX class (#4404)&lt;/li&gt; &lt;li&gt;Refinement patch parser (#4299)&lt;/li&gt; &lt;li&gt;Add python binding to &lt;code&gt;WarpXParticleContainer::sumParticleCharge&lt;/code&gt; (#4406)&lt;/li&gt; &lt;li&gt;[pre-commit.ci] pre-commit autoupdate (#4433)&lt;/li&gt; &lt;li&gt;Add paper using WarpX for laser-driven fusion (#4428)&lt;/li&gt; &lt;li&gt;AMReX: Weekly Update (#4431)&lt;/li&gt; &lt;li&gt;Fix unused variable with OpenPMD=OFF (#4421)&lt;/li&gt; &lt;li&gt;Doc: Laser Pulse Manip. for LPI (#4414)&lt;/li&gt; &lt;li&gt;Parallelize scraping (#4418)&lt;/li&gt; &lt;li&gt;Remove legacy references to EvolveEM which had been renamed Evolve (#4422)&lt;/li&gt; &lt;li&gt;Update AMReX to latest commit (#4423)&lt;/li&gt; &lt;li&gt;CI: Unbreak macOS (#4427)&lt;/li&gt; &lt;li&gt;AMReX/pyAMReX/PICSAR: Weekly Update (#4417)&lt;/li&gt; &lt;/ul&gt