10 research outputs found
Additional file 4 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 4: Table S4. Table of GO enrichment analysis after Bacillomycin D-C16 treatment versus control at time 12 h
Additional file 3 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 3: Table S3. Table of RNA-seq data after Bacillomycin D-C16 treatment versus control at time 24 h
Probiotic Yogurt Alleviates High-Fat Diet-Induced Lipid Accumulation and Insulin Resistance in Mice via the Adiponectin Pathway
A high-fat diet (HFD) easily contributes to the pathogenesis
of
obesity and insulin resistance. Obesity and insulin resistance have
been clinical and public health challenges all over the world. Probiotic-fermented
yogurt is one type of popular and functional beverage in people’s
daily lives. This study mainly explored the lipid- and glucose-lowering
effects of Lactobacillus acidophilus NX2-6-fermented yogurt (LA-Y) in HFD-fed mice. The results showed
that LA-Y administration improved the lipid profile in the serum and
liver, reduced fasting blood glucose levels, and enhanced insulin
sensitivity. Protein analysis showed that LA-Y treatment promoted
fatty acid oxidation and suppressed de novo lipogenesis in the adipose
tissue and liver. LA-Y effectively alleviated glucose metabolism disorders
by activating the insulin signaling pathway, suppressing gluconeogenesis
in the liver and muscle, reducing the concentration of pro-inflammatory
cytokines in the serum, and promoting glycolysis and gluconeogenesis
in the small intestine. LA-Y supplementation also promoted fat browning
via the adiponectin/AMPKα/PGC-1α/UCP1 pathway and enhanced
mitochondrial biogenesis in the liver and muscle by activating the
adiponectin/AdipoR1/APPL1/AMPKα/PGC-1α pathway, leading
to increased energy expenditure. Therefore, LA-Y may be a functional
dairy food for preventing and alleviating diet-induced metabolic disorders
Additional file 8 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 8: Table S8. Table of transcription factors after Bacillomycin D-C16 treatment versus control at time 12 h
Additional file 2 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 2: Table S2. Table of RNA-seq data after Bacillomycin D-C16 treatment versus control at time 12 h
Additional file 9 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 9: Table S9. Table of transcription factors after Bacillomycin D-C16 treatment versus control at time 24 h
Additional file 1 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 1: Table S1. Overview of the transcriptome sequencing dataset and quality check
Additional file 5 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 5: Table S5. Table of GO enrichment analysis after Bacillomycin D-C16 treatment versus control at time 24 h
Additional file 6 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 6: Table S6. Table of KEGG enrichment analysis after Bacillomycin D-C16 treatment versus control at time 12 h
Additional file 7 of Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato
Additional file 7: Table S7. Table of KEGG enrichment analysis after Bacillomycin D-C16 treatment versus control at time 24 h