Novel Mutation in Boy With Cartilage-hair Hypoplasia

BackgroundCartilage-hair hypoplasia (MIM 250250) is an autosomal recessive disease with diverse clinical manifestations. The clinical phenotypes include variable degrees of bone and hair dysplasia, deficient cellular and/or humoral immunity, and a predisposition to malignancy.MethodsWe performed genetic studies of a patient with disproportionate short stature and brittle scalp hair. Genetic studies were also carried out in the patient's parents.ResultsA novel maternal mutation that consisted of a duplication of 14 nucleotides at position −13 of the RNA component of the RNA component of mitochondrial RNA processing endoribonuclease gene (RMRP; g. −26 to −13 dupTACTACTCTGTGAA, promoter region) and a paternal mutation base substitution of C to T at nucleotide + 230 (designated as + 1 in the transcription initiation site) in the coding sequence of RMRP were detected in this patient.ConclusionA novel maternal RMRP mutation was found in a Chinese boy with typical cartilage-hair hypoplasia

A Handover Prediction Mechanism Based on LTE-A UE History Information

[[abstract]]In response to the rapidly developing of wireless communication technology, the deployed of eNB is denser and more complex. The research of how to handover accurately and fast in LTE-A are discussed much in recent years .In 3GPP Release 8, the UE History Information recorded by eNB was first proposed, it's proposed to provide eNB to judge the target eNB when handover. The history information includes the Cell ID and Time UE stayed in cell. We proposed an advance UE history information, reducing the handover failure rate and ping-pong handover rate by using the history information like Region-Domain, Time-Domain and Time To Trigger.[[sponsorship]]Tamkang University[[incitationindex]]EI[[conferencetype]]國際[[conferencetkucampus]]台北校園[[conferencedate]]20150902~20150903[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Taipei, Taiwa

A Fuzzy-based Dynamic Channel Allocation

[[abstract]]In traditional wireless networks, fixed allocation of spectrum is one of the main reason causing low utilization of spectrum. In order to solve this problem, a new wireless communication model has been proposed, which called Cognitive Radio Networks (CRN). CRN adopts Dynamic Spectrum Access (DSA) technology, thus it can flexibly use the spectrum which primary user temporarily unused. In cognitive radio networks, due to each secondary user (SU) has different location and surrounding spectrum environment, it may have variety of available channels. How to assign these available channels is the crucial point of system performance. However, existing methods doesn’t consider the problem of multipath fading; therefore, this study proposed an improved channel allocation scheme. We consider the received signal strength to define the channel access priority of secondary users applied by fuzzy theory. Finally, the simulation results show the superior of our approach and verify the effectiveness of the proposed scheme.[[sponsorship]]University of Colombo School of Computing, Sri Lanka[[incitationindex]]EI[[conferencetype]]國際[[conferencedate]]20150823~20150826[[booktype]]電子版[[iscallforpapers]]Y[[conferencelocation]]Colombo, Sri Lank

Developing Blue Ocean Strategy of Sustainable Product Design and Development for Business Opportunities of BOP Groups in Taiwan

This study expands the definition of the poor group and attempts to delve into and make known the phenomenon of poverty in Taiwan and aims to explore the goals and possibilities of the BOP consumer market. Through a questionnaire survey and expert interviews, this research adopts the concept of sustainability to discuss the lifestyle and consumption characteristics of the BOP group and establishes a design strategic norm of the sustainable products. The findings show that the BOP group in Taiwan is new poverty or working poor and high quality and common prices are the main requirements; these should be introduced into the development model of sustainable design

Structural study in Highly Compressed BiFeO3 Epitaxial Thin Films on YAlO3

We report a study on the thermodynamic stability and structure analysis of the epitaxial BiFeO3 (BFO) thin films grown on YAlO3 (YAO) substrate. First we observe a phase transition of MC-MA-T occurs in thin sample (<60 nm) with an utter tetragonal-like phase (denoted as MII here) with a large c/a ratio (~1.23). Specifically, MII phase transition process refers to the structural evolution from a monoclinic MC structure at room temperature to a monoclinic MA at higher temperature (150oC) and eventually to a presence of nearly tetragonal structure above 275oC. This phase transition is further confirmed by the piezoforce microscopy measurement, which shows the rotation of polarization axis during the phase transition. A systematic study on structural evolution with thickness to elucidate the impact of strain state is performed. We note that the YAO substrate can serve as a felicitous base for growing T-like BFO because this phase stably exists in very thick film. Thick BFO films grown on YAO substrate exhibit a typical "morphotropic-phase-boundary"-like feature with coexisting multiple phases (MII, MI, and R) and a periodic stripe-like topography. A discrepancy of arrayed stripe morphology in different direction on YAO substrate due to the anisotropic strain suggests a possibility to tune the MPB-like region. Our study provides more insights to understand the strain mediated phase co-existence in multiferroic BFO system.Comment: 18 pages, 6 figures, submitted to Journal of Applied Physic

Construct the destination image formation model of Macao: the case of Taiwan tourists to Macao

The investigation based on the vigorous tourism industry and open up the gaming industry in the future to promote and construct the nation competition strength in Taiwan. Tourism destination image is an important factor which tourist chooses and plans their tourism schedule. But the concept of image includes inner psychology motivation, external environment factor or these two factors interaction to develop and integrate model. Therefore, this investigation aimed to construct the destination image formation model of Macao and take the Taiwan visitors to Macao for example. According to the findings, Taiwan tourists who actually visited Macao generally report positive tourist image in overall. Furthermore, the overall image of tourists visiting Macao can be enhanced if consumers’ return on investment and service superiority are conducted through experiential value perspective in terms of value/environment variables of Taiwan tourists’ perception or cognition perspective. Finally, a tourism image of Macao perceived by Taiwan tourists is built upon an experience in integrated industry surrounded by luxury atmosphere. To feel about the casino culture of mirage among Asian cities, and a national image of sense and sensibility after combining Eastern and Western culture are primary tourism motives of the study

Associations between child maltreatment, PTSD, and internet addiction among Taiwanese students

AbstractThis study examines (1) the associations between multiple types of child maltreatment and Internet addiction, and (2) the mediating effects of post-traumatic stress disorder (PTSD) on these associations. We collected data from a national proportionately stratified random sample of 6233 fourth-grade students in Taiwan in 2014. We conducted bivariate correlations and sets of multiple regression analyses to examine the associations between multiple types of maltreatment (5 types in total) and Internet addiction, and to identify the mediating role of PTSD. The results reveal that being male and experiencing abuse (psychological neglect, physical neglect, paternal physical violence, sexual violence) were associated with increased risk among children of developing PTSD and Internet addiction. Moreover, PTSD mediated the associations between multiple types of maltreatment (except maternal physical violence) and Internet addiction. This study demonstrates (1) the effects of multiple types of maltreatment on the PTSD and Internet addiction of children and (2) the importance of early prevention and intervention in addressing related public-health concerns