A: Scan from a 40-year-old healthy individual.

<p>The diameter of the vessel is 7.5 mm, and the IMT is 0.64 mm. B: Scan from a 38-year old nasopharyngeal carcinoma patient with temporal lobe necrosis after radiotherapy shows narrowed vessel lumen (d = 2.2 mm, IMT = 7 mm) and the atherosclerotic plaque. It shows a more than 76% reduction in luminal diameter. Plaque is displayed with arrowhead.</p

Demographic and clinical characteristics of the three groups.

<p>Demographic and clinical characteristics of the three groups.</p

Flow velocities of ICAs among three groups.

<p>*Significant difference is found between Group 1 and control group (p<0.001). **Significant difference is found between Group 2 and control group (p<0.001).</p

Prevalence of plaque in ICAs in the three groups.

<p>Group 1 = patients with radiation-induced temporal lobe necrosis; Group 2 = Patients without radiation-induced temporal lobe necrosis; Abbreviation: RICA =  right internal carotid artery; LICA = left internal carotid artery.</p

Flow velocities of MCAs and BA among three groups.

<p>*The flow velocities of MCAs in Group 1 are much faster than those in control group (p<0.001). ** The flow velocities of MCAs in Group 2 are much faster than those in control group (p<0.001). Also, there is significant difference in MCAs flow velocities between Group 1 and Group 2 (p<0.001).</p