1,3-Dimethyl 5-(4,4,5,5-tetra­methyl-1,3,2-dioxaborolan-2-yl)benzene-1,3-dicarboxyl­ate

The title compound, C16H21BO6, has has approximate C 2 symmetry, but no crystallographically imposed mol­ecular symmetry. In the crystal, mol­ecules are packed into parallel columns along the a axis. Short inter­molecular C—H⋯O contacts stabilize the crystal packing

HyExo:A Novel Quasi-Passive Hydraulic Exoskeleton for Load-Carrying Augmentation

The development of assistive lower-limb exoskeletons gains prominence for human load-carrying augmentation. Hydraulic transmission has attractive hydrostatic features and lower inertia at the end of human limbs. However, few hydraulic lower-limb exoskeletons were developed with low energy consumption and light weight. In this article, we introduce HyExo, a quasi-passive hydraulic exoskeleton that is built on a lightweight rotary cage valve (RCV) block with a fast response and low energy consumption of 1.55&amp;#x00A0;W. Based on the RCV block, we propose an optimization-based regulator for joint energy distribution to harvest and release the hydraulic energy among joints during the stance phase. The interaction force model and control of the novel nonanthropomorphic structure are presented and evaluated. The load-supporting effect was investigated and validated through human subject experiments. The results show that with an assisting fluid pressure of 2.5&amp;#x00A0;MPa, HyExo can transfer a mean force of 237&amp;#x00A0;N to the ground. Meanwhile, the impact of wearing HyExo on gait is analyzed. The metabolic expenditure test shows that HyExo can slow the increasing rate in metabolic cost as load increases. Compared with a regular backpack, walking with HyExo to carry 30&amp;#x00A0;kg of weight reduces wearers&amp;#x0027; metabolic energy expenditure by 7.8&amp;#x0025;.</p

Antioxidant and Preventive Effects of Extract from Nymphaea candida Flower on In Vitro Immunological Liver Injury of Rat Primary Hepatocyte Cultures

Nymphaea candida is traditional Uighur medicine that is commonly used to treat head pains, cough, hepatitis and hypertension in Xinjiang of China. In this article, the extract of N. candida was measured for antioxidant activity, using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals scavenging assay and reducing power determination, and compared with those of the positive controls of butylated hydroxytoluene (BHT) and gallic acid (GA). The active extract was further purified by liquid-liquid partition to afford four fractions, of which the ethyl acetate-soluble (EA) fraction (NCE) exhibited the strongest antioxidant capacity with IC50 value of 12.6 μg/mL for DPPH. Thirteen phenolic compounds were isolated from this fraction, and they all showed significant antioxidant activities in DPPH model system. Furthermore, NCE showed potent antioxidant capacity with IC50 value of 59.32 μg/mL, 24.48 μg/mL and 86.85 μg/mL, for O2−, ·OH and H2O2 radicals, respectively. Moreover, NCE on BCG plus LPS-induced immunological liver injury was evaluated using primary cultured rat hepatocytes. NCE produced significant hepatoprotective effects as evidenced by decreased supernatant enzyme activities (AST—aspartate transaminase, P <  .01; ALT—alanine transferase, P <  .01) and nitric oxide (NO, P <  .01) production. These results revealed the in vitro antioxidant and hepatoprotective activities of NCE against immunological liver injury. Further investigations are necessary to verify these activities in vivo