Nucleosynthesis in Advective Accretion Disks Around Galactic and Extra-Galactic Black Holes

We compute the nucleosynthesis of materials inside advective disks around black holes. We show that composition of incoming matter can change significantly depending on the accretion rate and accretion disks. These works are improvements on the earlier works in thick accretion disks of Chakrabarti, Jin & Arnett (1987) in presence of advection in the flow.Comment: Latex pages including figures. Kluwer Style files included. Appearing in `Observational Evidence for Black Holes in the Universe', ed. Sandip K. Chakrabarti, Kluwer Academic Publishers (DORDRECHT: Holland

The Risk of Type 2 Diabetes Mellitus in a Russian Population Cohort According to Data from the HAPIEE Project

The aim of this study is to investigate the 14-year risk of type 2 diabetes mellitus (T2DM) and develop a risk score for T2DM in the Siberian cohort. A random population sample (males/females, 45–69 years old) was examined at baseline in 2003–2005 (Health, Alcohol, and Psychosocial Factors in Eastern Europe (HAPIEE) project, n = 9360, Novosibirsk) and re-examined in 2006–2008 and 2015–2017. After excluding those with baseline T2DM, the final analysis included 7739 participants. The risk of incident T2DM during a 14-year follow-up was analysed using Cox regression. In age-adjusted models, male and female hazard ratios (HR) of incident T2DM were 5.02 (95% CI 3.62; 6.96) and 5.13 (95% CI 3.56; 7.37) for BMI ≥ 25 kg/m2; 4.38 (3.37; 5.69) and 4.70 (0.27; 6.75) for abdominal obesity (AO); 3.31 (2.65; 4.14) and 3.61 (3.06; 4.27) for fasting hyperglycaemia (FHG); 2.34 (1.58; 3.49) and 3.27 (2.50; 4.26) for high triglyceride (TG); 2.25 (1.74; 2.91) and 2.82 (2.27; 3.49) for hypertension (HT); and 1.57 (1.14; 2.16) and 1.69 (1.38; 2.07) for family history of diabetes mellitus (DM). In addition, secondary education, low physical activity (PA), and history of cardiovascular disease (CVD) were also significantly associated with T2DM in females. A simple T2DM risk calculator was generated based on non-laboratory parameters. A scale with the best quality included waist circumference >95 cm, HT history, and family history of T2DM (area under the curve (AUC) = 0.71). The proposed 10-year risk score of T2DM represents a simple, non-invasive, and reliable tool for identifying individuals at a high risk of future T2DM

The formation of cores in galaxies across cosmic time – the existence of cores is not in tension with the ΛCDM paradigm

The 'core-cusp' problem is considered a key challenge to the ΛCDM paradigm. Haloes in dark matter only simulations exhibit 'cuspy' profiles, where density continuously increases towards the centre. However, the dark matter profiles of many observed galaxies (particularly in the dwarf regime) deviate strongly from this prediction, with much flatter central regions ('cores'). We use NewHorizon (NH), a hydrodynamical cosmological simulation, to investigate core formation, using a statistically significant number of galaxies in a cosmological volume. Haloes containing galaxies in the upper (M⋆ ≥ 1010.2 M⊙) and lower (M⋆ ≤ 108 M⊙) ends of the stellar mass distribution contain cusps. However, Haloes containing galaxies with intermediate (108 M⊙ ≤ M⋆ ≤ 1010.2 M⊙) stellar masses are generally cored, with typical halo masses between 1010.2 M⊙ and 1011.5 M⊙. Cores form through supernova-driven gas removal from halo centres, which alters the central gravitational potential, inducing dark matter to migrate to larger radii. While all massive (M⋆ ≥ 109.5 M⊙) galaxies undergo a cored-phase, in some cases cores can be removed and cusps reformed. This happens if a galaxy undergoes sustained star formation at high redshift, which results in stars (which, unlike the gas, cannot be removed by baryonic feedback) dominating the central gravitational potential. After cosmic star formation peaks, the number of cores, and the mass of the Haloes they are formed in, remain constant, indicating that cores are being routinely formed over cosmic time after a threshold halo mass is reached. The existence of cores is, therefore, not in tension with the standard paradigm

Blockchain Applicability for the Internet of Things: Performance and Scalability Challenges and Solutions

Blockchain has recently been able to draw wider attention throughout the research community. Since its emergence, the world has seen the mind-blowing expansion of this new technology, which was initially developed as a pawn of digital currency more than a decade back. A self-administering ledger that ensures extensive data immutability over the peer-to-peer network has made it attractive for cybersecurity applications such as a sensor-enabled system called the Internet of things (IoT). Brand new challenges and questions now demand solutions as huge IoT devices are now online in a distributed fashion to ease our everyday lives. After being motivated by those challenges, the work here has figured out the issues and perspectives an IoT infrastructure can suffer because of the wrong choice of blockchain technology. Though it may look like a typical review, however, unlike that, this paper targets sorting out the specific security challenges of the blockchain-IoT eco-system through critical findings and applicable use-cases. Therefore, the contribution includes directing Blockchain architects, designers, and researchers in the broad domain to select the unblemished combinations of Blockchain-powered IoT applications. In addition, the paper promises to bring a deep insight into the state-of-the-art Blockchain platforms, namely Ethereum, Hyperledger, and IOTA, to exhibit the respective challenges, constraints, and prospects in terms of performance and scalability

Aharonov-Bohm interference in topological insulator nanoribbons

Topological insulators represent novel phases of quantum matter with an insulating bulk gap and gapless edges or surface states. The two-dimensional topological insulator phase was predicted in HgTe quantum wells and confirmed by transport measurements. Recently, Bi2Se3 and related materials have been proposed as three-dimensional topological insulators with a single Dirac cone on the surface and verified by angle-resolved photoemission spectroscopy experiments. Here, we show unambiguous transport evidence of topological surface states through periodic quantum interference effects in layered single-crystalline Bi2Se3 nanoribbons. Pronounced Aharonov-Bohm oscillations in the magnetoresistance clearly demonstrate the coverage of two-dimensional electrons on the entire surface, as expected from the topological nature of the surface states. The dominance of the primary h/e oscillation and its temperature dependence demonstrate the robustness of these electronic states. Our results suggest that topological insulator nanoribbons afford novel promising materials for future spintronic devices at room temperature.Comment: 5 pages, 4 figures, RevTex forma

Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp maritima: from traditional remedies to prospective products

This work explored the biotechnological potential of the medicinal halophyte Artemisia campestris subsp. maritima (dune wormwood) as a source of health promoting commodities. For that purpose, infusions, decoctions and tinctures were prepared from roots and aerial-organs and evaluated for in vitro antioxidant, anti-diabetic and tyrosinase-inhibitory potential, and also for polyphenolic and mineral contents and toxicity. The dune wormwood extracts had high polyphenolic content and several phenolics were identified by ultra-high performance liquid chromatography-photodiode array-mass-spectrometry (UHPLC-PDA-MS). The main compounds were quinic, chlorogenic and caffeic acids, coumarin sulfates and dicaffeoylquinic acids; several of the identified phytoconstituents are here firstly reported in this A. campestris subspecies. Results obtained with this plant's extracts point to nutritional applications as mineral supplementary source, safe for human consumption, as suggested by the moderate to low toxicity of the extracts towards mammalian cell lines. The dune wormwood extracts had in general high antioxidant activity and also the capacity to inhibit a-glucosidase and tyrosinase. In summary, dune wormwood extracts are a significant source of polyphenolic and mineral constituents, antioxidants and a-glucosidase and tyrosinase inhibitors, and thus, relevant for different commercial segments like the pharmaceutical, cosmetic and/or food industries.FCT - Foundation for Science and Technology [CCMAR/Multi/04326/2013]; Portuguese National Budget; FCT [IF/00049/2012, SFRH/BD/94407/2013]; Research Foundation - Flanders (FWO) [12M8315N]info:eu-repo/semantics/publishedVersio

Contact Manifolds, Contact Instantons, and Twistor Geometry

Recently, Kallen and Zabzine computed the partition function of a twisted supersymmetric Yang-Mills theory on the five-dimensional sphere using localisation techniques. Key to their construction is a five-dimensional generalisation of the instanton equation to which they refer as the contact instanton equation. Subject of this article is the twistor construction of this equation when formulated on K-contact manifolds and the discussion of its integrability properties. We also present certain extensions to higher dimensions and supersymmetric generalisations.Comment: v3: 28 pages, clarifications and references added, version to appear in JHE

Diffractive Higgs Production by AdS Pomeron Fusion

The double diffractive Higgs production at central rapidity is formulated in terms of the fusion of two AdS gravitons/Pomerons first introduced by Brower, Polchinski, Strassler and Tan in elastic scattering. Here we propose a simple self-consistent holographic framework capable of providing phenomenologically compelling estimates of diffractive cross sections at the LHC. As in the traditional weak coupling approach, we anticipate that several phenomenological parameters must be tested and calibrated through factorization for a self-consistent description of other diffractive process such as total cross sections, deep inelastic scattering and heavy quark production in the central region.Comment: 53 pages, 8 figure

Signal transducer and activator of transcription 3-mediated CD133 up-regulation contributes to promotion of hepatocellular carcinoma

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