9,527 research outputs found
Livestock products in the Third World: past trends and projections to 1990 and 2000
Meat industry and trade Developing countries Statistics., Dairy products industry Developing countries Statistics., Meat industry and trade Developing countries Forecasting Statistical methods., Dairy products industry Developing countries Forecasting Statistical methods.,
Coarsening Dynamics of a One-Dimensional Driven Cahn-Hilliard System
We study the one-dimensional Cahn-Hilliard equation with an additional
driving term representing, say, the effect of gravity. We find that the driving
field has an asymmetric effect on the solution for a single stationary
domain wall (or `kink'), the direction of the field determining whether the
analytic solutions found by Leung [J.Stat.Phys.{\bf 61}, 345 (1990)] are
unique. The dynamics of a kink-antikink pair (`bubble') is then studied. The
behaviour of a bubble is dependent on the relative sizes of a characteristic
length scale , where is the driving field, and the separation, ,
of the interfaces. For the velocities of the interfaces are
negligible, while in the opposite limit a travelling-wave solution is found
with a velocity . For this latter case () a set of
reduced equations, describing the evolution of the domain lengths, is obtained
for a system with a large number of interfaces, and implies a characteristic
length scale growing as . Numerical results for the domain-size
distribution and structure factor confirm this behavior, and show that the
system exhibits dynamical scaling from very early times.Comment: 20 pages, revtex, 10 figures, submitted to Phys. Rev.
Dynamics of Ordering of Heisenberg Spins with Torque --- Nonconserved Case. I
We study the dynamics of ordering of a nonconserved Heisenberg magnet. The
dynamics consists of two parts --- an irreversible dissipation into a heat bath
and a reversible precession induced by a torque due to the local molecular
field. For quenches to zero temperature, we provide convincing arguments, both
numerically (Langevin simulation) and analytically (approximate closure scheme
due to Mazenko), that the torque is irrelevant at late times. We subject the
Mazenko closure scheme to systematic numerical tests. Such an analysis, carried
out for the first time on a vector order parameter, shows that the closure
scheme performs respectably well. For quenches to , we show, to , that the torque is irrelevant at the Wilson-Fisher fixed
point.Comment: 13 pages, REVTEX, and 19 .eps figures, compressed, Submitted to Phys.
Rev.
The identification of mitochondrial DNA variants in glioblastoma multiforme
Background:
Mitochondrial DNA (mtDNA) encodes key proteins of the electron transfer chain (ETC), which produces ATP through oxidative phosphorylation (OXPHOS) and is essential for cells to perform specialised functions. Tumor-initiating cells use aerobic glycolysis, a combination of glycolysis and low levels of OXPHOS, to promote rapid cell proliferation and tumor growth. Glioblastoma multiforme (GBM) is an aggressively malignant brain tumor and mitochondria have been proposed to play a vital role in GBM tumorigenesis.
Results:
Using next generation sequencing and high resolution melt analysis, we identified a large number of mtDNA variants within coding and non-coding regions of GBM cell lines and predicted their disease-causing potential through in silico modeling. The frequency of variants was greatest in the D-loop and origin of light strand replication in non-coding regions. ND6 was the most susceptible coding gene to mutation whilst ND4 had the highest frequency of mutation. Both genes encode subunits of complex I of the ETC. These variants were not detected in unaffected brain samples and many have not been previously reported. Depletion of HSR-GBM1 cells to varying degrees of their mtDNA followed by transplantation into immunedeficient mice resulted in the repopulation of the same variants during tumorigenesis. Likewise, de novo variants identified in other GBM cell lines were also incorporated. Nevertheless, ND4 and ND6 were still the most affected genes. We confirmed the presence of these variants in high grade gliomas.
Conclusions:
These novel variants contribute to GBM by rendering the ETC. partially dysfunctional. This restricts metabolism to anaerobic glycolysis and promotes cell proliferation
Spinodal Decomposition and the Tomita Sum Rule
The scaling properties of a phase-ordering system with a conserved order
parameter are studied. The theory developed leads to scaling functions
satisfying certain general properties including the Tomita sum rule. The theory
also gives good agreement with numerical results for the order parameter
scaling function in three dimensions. The values of the associated
nonequilibrium decay exponents are given by the known lower bounds.Comment: 15 pages, 6 figure
Macrorealism from entropic Leggett-Garg inequalities
We formulate entropic Leggett-Garg inequalities, which place constraints on
the statistical outcomes of temporal correlations of observables. The
information theoretic inequalities are satisfied if macrorealism holds. We show
that the quantum statistics underlying correlations between time-separated spin
component of a quantum rotor mimics that of spin correlations in two spatially
separated spin- particles sharing a state of zero total spin. This brings
forth the violation of the entropic Leggett-Garg inequality by a rotating
quantum spin- system in similar manner as does the entropic Bell inequality
(Phys. Rev. Lett. 61, 662 (1988)) by a pair of spin- particles forming a
composite spin singlet state.Comment: 5 pages, RevTeX, 2 eps figures, Accepted for publication in Phys.
Rev.
Drink alcohol and dim the lights: The impact of cognitive deficits on medial frontal cortex function
Fast Domain Growth through Density-Dependent Diffusion in a Driven Lattice Gas
We study electromigration in a driven diffusive lattice gas (DDLG) whose
continuous Monte Carlo dynamics generate higher particle mobility in areas with
lower particle density. At low vacancy concentrations and low temperatures,
vacancy domains tend to be faceted: the external driving force causes large
domains to move much more quickly than small ones, producing exponential domain
growth. At higher vacancy concentrations and temperatures, even small domains
have rough boundaries: velocity differences between domains are smaller, and
modest simulation times produce an average domain length scale which roughly
follows , where varies from near .55 at 50% filling
to near .75 at 70% filling. This growth is faster than the behavior
of a standard conserved order parameter Ising model. Some runs may be
approaching a scaling regime. At low fields and early times, fast growth is
delayed until the characteristic domain size reaches a crossover length which
follows . Rough numerical estimates give and simple theoretical arguments give . Our conclusion that
small driving forces can significantly enhance coarsening may be relevant to
the YBCuO electromigration experiments of Moeckly {\it et
al.}(Appl. Phys. Let., {\bf 64}, 1427 (1994)).Comment: 18 pages, RevTex3.
Evolution of speckle during spinodal decomposition
Time-dependent properties of the speckled intensity patterns created by
scattering coherent radiation from materials undergoing spinodal decomposition
are investigated by numerical integration of the Cahn-Hilliard-Cook equation.
For binary systems which obey a local conservation law, the characteristic
domain size is known to grow in time as with n=1/3,
where B is a constant. The intensities of individual speckles are found to be
nonstationary, persistent time series. The two-time intensity covariance at
wave vector can be collapsed onto a scaling function , where and . Both analytically and numerically, the covariance
is found to depend on only through in the
small- limit and in the large-
limit, consistent with a simple theory of moving interfaces that applies to any
universality class described by a scalar order parameter. The speckle-intensity
covariance is numerically demonstrated to be equal to the square of the
two-time structure factor of the scattering material, for which an analytic
scaling function is obtained for large In addition, the two-time,
two-point order-parameter correlation function is found to scale as
, even for quite large
distances . The asymptotic power-law exponent for the autocorrelation
function is found to be , violating an upper bound
conjectured by Fisher and Huse.Comment: RevTex: 11 pages + 12 figures, submitted to PR
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