Effects of age of acquisition and semantic transparency on reading characters in Chinese dyslexia

This study examined the effects of the age of acquisition (AOA) and semantic transparency on the reading aloud ability of a Chinese dyslexic individual, TWT, who relied on the semantic pathway to name characters. Both AOA and semantic transparency significantly predicted naming accuracy and distinguished the occurrence of correct responses and semantic errors from other errors. A post hoc analysis of subsets of items orthogonally varied in the AOA and semantic transparency revealed an interaction between the two variables. These findings converge on reports of AOA and semantic effects on deep dyslexic individuals reading alphabetic scripts. The case of TWT, together with recent results of another Chinese dyslexic individual who reads via the nonsemantic route and exhibits the effects of AOA and phonological consistency, supports the arbitrary mapping hypothesis, which states that the AOA effect resides in the connection between two levels of representation. © Cambridge University Press 2010.published_or_final_versio

Dynamics of scalar dissipation in isotropic turbulence: a numerical and modelling study

The physical mechanisms underlying the dynamics of the dissipation of passive scalar fluctuations with a uniform mean gradient in stationary isotropic turbulence are studied using data from direct numerical simulations (DNS), at grid resolutions up to 5123. The ensemble-averaged Taylor-scale Reynolds number is up to about 240 and the Schmidt number is from ⅛ to 1. Special attention is given to statistics conditioned upon the energy dissipation rate because of their important role in the Lagrangian spectral relaxation (LSR) model of turbulent mixing. In general, the dominant physical processes are those of nonlinear amplification by strain rate fluctuations, and destruction by molecular diffusivity. Scalar dissipation tends to form elongated structures in space, with only a limited overlap with zones of intense energy dissipation. Scalar gradient fluctuations are preferentially aligned with the direction of most compressive strain rate, especially in regions of high energy dissipation. Both the nature of this alignment and the timescale of the resulting scalar gradient amplification appear to be nearly universal in regard to Reynolds and Schmidt numbers. Most of the terms appearing in the budget equation for conditional scalar dissipation show neutral behaviour at low energy dissipation but increased magnitudes at high energy dissipation. Although homogeneity requires that transport terms have a zero unconditional average, conditional molecular transport is found to be significant, especially at lower Reynolds or Schmidt numbers within the simulation data range. The physical insights obtained from DNS are used for a priori testing and development of the LSR model. In particular, based on the DNS data, improved functional forms are introduced for several model coefficients which were previously taken as constants. Similar improvements including new closure schemes for specific terms are also achieved for the modelling of conditional scalar variance

Improved Lagrangian mixing models for passive scalars in isotropic turbulence

Lagrangian data for velocity, scalars, and energy and scalar dissipation from direct numerical simulations are used to validate Lagrangian mixing models for inert passive scalars in stationary isotropic turbulence. The scalar fluctuations are nearly Gaussian, and, as a result of production by uniform mean gradients, statistically stationary. Comparisons are made for Taylor-scale Reynolds numbers in the range 38 to about 240 and Schmidt numbers in the range 1/8 to 1. Model predictions for one-point, one-time Eulerian statistics ~Eulerian correspondence! and one-particle, two-time Lagrangian statistics ~Lagrangian correspondence! are examined. Two scalar mixing models, namely the Lagrangian Fokker–Planck model and the Lagrangian colored-noise ~LCN! model, are proposed and written in terms of stochastic differential equations ~SDE! with specified drift and diffusion terms. Both of these models rely on statistics of the scalar field conditioned upon the energy dissipation, as provided by the Lagrangian spectral relaxation ~LSR! model. With the exception of the scalar dissipation, the models are shown to capture the Reynolds and Schmidt-number dependence of the Lagrangian integral time scales. However, the LCN model provides a more realistic description of the Lagrangian scalar fluctuations as differentiable time series having the correct form of the scalar autocorrelation function. Further extensions of the new mixing models to non-Gaussian scalars are conceptually straightforward, but require a closure for the scalar-conditioned scalar dissipation rate matrix. Likewise, accurate prediction of joint statistics for differential diffusion between different scalars with unequal molecular diffusivities will require the formulation of a multiscale SDE similar to the LSR model

Measurement of Lagrangian velocity in fully developed turbulence

We have developed a new experimental technique to measure the Lagrangian velocity of tracer particles in a turbulent flow, based on ultrasonic Doppler tracking. This method yields a direct access to the velocity of a single particule at a turbulent Reynolds number $R_{\lambda} = 740$. Its dynamics is analyzed with two decades of time resolution, below the Lagrangian correlation time. We observe that the Lagrangian velocity spectrum has a Lorentzian form $E^{L}(\omega) = u_{rms}^{2} T_{L} / (1 + (T_{L}\omega)^{2})$, in agreement with a Kolmogorov-like scaling in the inertial range. The probability density function (PDF) of the velocity time increments displays a change of shape from quasi-Gaussian a integral time scale to stretched exponential tails at the smallest time increments. This intermittency, when measured from relative scaling exponents of structure functions, is more pronounced than in the Eulerian framework.Comment: 4 pages, 5 figures. to appear in PR

Anti-beta2 glycoprotein I (beta2GPI) antibodies facilitates phagocytosis of apoptotic neutrophils in patients with systemic lupus erythematosus (SLE)

BACKGROUND : Increased apoptosis provides a continuous source autoantigens and has been suggested to have a pathogenic role in SLE. We have previously shown patients with SLE have impaired clearance of apoptotic bodies. In this study, we evaluated whether anti-beta2GPI antibodies, a subset of antiphospholipid antibodies, may have an effect on the phagocytosis of apoptotic bodies by macrophages in these patients …published_or_final_versio

Optimal Location of Sources in Transportation Networks

We consider the problem of optimizing the locations of source nodes in transportation networks. A reduction of the fraction of surplus nodes induces a glassy transition. In contrast to most constraint satisfaction problems involving discrete variables, our problem involves continuous variables which lead to cavity fields in the form of functions. The one-step replica symmetry breaking (1RSB) solution involves solving a stable distribution of functionals, which is in general infeasible. In this paper, we obtain small closed sets of functional cavity fields and demonstrate how functional recursions are converted to simple recursions of probabilities, which make the 1RSB solution feasible. The physical results in the replica symmetric (RS) and the 1RSB frameworks are thus derived and the stability of the RS and 1RSB solutions are examined.Comment: 38 pages, 18 figure

Observing two dark accelerators around the Galactic Centre with Fermi Large Area Telescope

We report the results from a detailed $\gamma-$ray investigation in the field of two "dark accelerators", HESS J1745-303 and HESS J1741-302, with $6.9$ years of data obtained by the Fermi Large Area Telescope. For HESS J1745-303, we found that its MeV-GeV emission is mainly originated from the "Region A" of the TeV feature. Its $\gamma-$ray spectrum can be modeled with a single power-law with a photon index of $\Gamma\sim2.5$ from few hundreds MeV to TeV. Moreover, an elongated feature, which extends from "Region A" toward northwest for $\sim1.3^{\circ}$, is discovered for the first time. The orientation of this feature is similar to that of a large scale atomic/molecular gas distribution. For HESS J1741-302, our analysis does not yield any MeV-GeV counterpart for this unidentified TeV source. On the other hand, we have detected a new point source, Fermi J1740.1-3013, serendipitously. Its spectrum is apparently curved which resembles that of a $\gamma-$ray pulsar. This makes it possibly associated with PSR B1737-20 or PSR J1739-3023.Comment: 11 pages, 7 figures, 2 tables, accepted for publication in MNRA