16 research outputs found
Inhibition of synovial fibroblast production of IL-6 by triptolide, an active ingredient of Trypterygyium Wilfordii hook F
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Alterations of CD8+CD28- T cells in systemic lupus erythematosus and rheumatoid arthritis
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Anti-beta2 glycoprotein I (beta2GPI) antibodies facilitates phagocytosis of apoptotic neutrophils in patients with systemic lupus erythematosus (SLE)
BACKGROUND : Increased apoptosis provides a continuous source autoantigens and has been suggested to have a pathogenic role in SLE. We have previously shown patients with SLE have impaired clearance of apoptotic bodies. In this study, we evaluated whether anti-beta2GPI antibodies, a subset of antiphospholipid antibodies, may have an effect on the phagocytosis of apoptotic bodies by macrophages in these patients …published_or_final_versio
Sex hormones and apoptosis and immunoglobulin production in systemic lupus erythematosus
BACKGROUND: SLE is an autoimmune disease that affects predominantly female of reproductive age. Previous studies have suggested an immunomodulatory role of sex hormones in the pathogenesis of SLE. Objectives: To examine the effects of various sex hormones on apoptosis and immunoglobulin production by peripheral blood mononuclear cells (PBMCs) in SLE patients …published_or_final_versio
Effects of triptolide, an active ingredient of trypterygium Wilfordii Hook F (Thunder God Vine, a traditional Chinese herb), on rheumatoid synovial fibroblast function
published_or_final_versio