The second case of Horn Kolb Syndrome in the same woman in Turkey, diagnosed prenatally at 16 weeks of pregnancy

Background Acheiropodia is a rare form of skeletal dysplasias. It is characterized by the amputation of the upper and lower extremities and with aplasia of the hands and feet. Acheiropodia formerly was known as a disease affecting only people of Brazilian ancestry. The first case out of Brazil was reported from our clinic in 2012. In the present report, we summarize the second case of acheiropodia, which was diagnosed prenatally in the same patient. Case A 39 years old G7P2A4 pregnant woman admitted to our clinic for a regular obstetrics visit at 16th weeks gestation in May 2013. Her history was significant for early pregnancy oligohydramnios with fetal loss. In the post-abortion examination, the fetus was found to be affected with acheiropodia. Since she had a history of acheiropodia a detailed ultrasound examination was performed. The fetal head and body including the intra-cranial, thoracic and abdominal structures were normal; however, distal long bones of the upper and the lower extremities could not be demonstrated. Three days later she was admitted with vaginal bleeding. Post abortion macroscopic examination revealed the absence of distal parts of the both upper and lower extremities without any other demonstrable anomalies. Conclusion Acheiropodia is a rare disease which may be seen outside of South America. Evaluation of the continuity and normal appearance of the extremities should be integrated to the routine antenatal ultrasound examination

Meckel Gruber Syndrome diagnosed in two consecutive pregnancies

Meckel Gruber syndrome is a lethal, autosomal recessive, multisystemic disorder that is associated with a mutation affecting ciliogenesis. In this report, we present two consecutive pregnancies of a woman complicated with MKS. In the first pregnancy with MKS, the amniotic fluid index was under 1 cm with bilateral polycystic fetal kidneys. Post-abortion macroscopic examination of the first fetus revealed multiple congenital anomalies including occipital encephalocele, axial polydactyly and pes equinovarus. Ultrasound examination during the second gestation revealed a singleton pregnancy complicated by MKS. There were multiple congenital anomalies including an occipital encephalocele, polycystic and horseshoe shaped kidneys, axial polydactyly, cleft lip and palate

Severe ovarian hyperstimulation syndrome in spontaneous pregnancy treated successfully with cabergoline

Ovarian hyperstimulation syndrome (OHSS) is a relatively common complication in infertile patients treated with exogenous gonadotropins. Ovarian hyperstimulation in spontaneous pregnancies is a rare but possible. The pathogenesis of spontaneous OHSS is not well known. Risk factors for OHSS are young age, polycystic ovaries, low body mass index, high gonadotropin dose, increased estradiol and human chorionic gonadotropin levels, multiple pregnancy, OHSS history, molar pregnancy and hypothyroidism. In this report we present a case of severe spontaneous OHSS with a brief summary of the literature. She was hospitalized and treated in the clinic with the diagnosis of severe OHSS accompanying spontaneous pregnancy

Prenatal diagnosis of fetal acrania using two and three dimensional ultrasound

Malformations of the central nervous system are one of the most common congenital anomalies of the fetus. In this report we aimed to summarize a case of fetal acrania diagnosed in the first trimester and the use of two and three-dimensional ultrasound in early diagnosis of the disease

Effect of Modification of Lifestyle on Reproductive Potential Yașam Tarzı Değișikliğinin Üreme Potansiyeline Etkisi

ABSTRAC

Comparison of Single Incision and Conventional Laparoscopic Surgery for Surgical Sterilization

Objective: To compare the intraoperative characteristics and postoperative pain levels of single incision and conventional laparoscopic surgeries performed for surgical sterilization. Study Design: A single center prospective observational study was conducted to compare the conventional and single incision laparoscopic (SIL) partial salpingectomies performed for surgical tubal sterilization. In total of 110 women, 62 in the conventional laparoscopy and 48 in the SILS group participated in the study. The main outcome measures were peritoneal entry time, total operation time, amount of bleeding, intraoperative complications, post-operative pain scores, additional analgesic requirements, and length of hospital stay. Statistical analysis was accomplished using the chi-square test or Mann Whitney U test, where appropriate. Results: Demographical findings did not differ between the two groups (p>0.05). Similarly, total operation time, rates of intraoperative complications, conversion to laparotomy, length of hospital stay, pre and postoperative hematocrit levels were not significantly different between the groups. Peritoneal entry time was shorter in the SIL group (7.1 min. vs. 4.8 min., p<0.001). Additional analgesic requirements, postoperative pain scores in the recovery room and at 6th, 12th, and 24th hours were not different between the groups (p>0.05). Conclusion: SILS seems a safe and feasible alternative to conventional laparoscopy for surgical tubal sterilization. Keywords: Partial salpingectomy, Tubal ligation, Contraception, Surgical sterilization, Single Incision Laparoscop

Renal Failure in Pregnancy: Case Reports and Review of the Literature

Acute renal failure (ARF) is rarely associated with pregnancy. However, it is a severe health-deteriorating problem of pregnant women without a known kidney disease. Although its incidence is relatively low in developed countries (1/20000), it is still a serious health issue in the developing world. In addition to any of the etiological factors that may result in ARF in non-pregnant women, pregnancy also increases the vulnerability of some special diseases that may result with the renal injury. In this review we aimed to summarize antepartum and postpartum causes of renal failure via summarizing two cases of renal failure

Feasibility of single-incision laparoscopy for ruptured ectopic pregnancies with hemoperitoneum

<p><b>Background:</b> The aim of this study was to compare single-incision laparoscopic surgery (SILS) and conventional laparoscopy in ectopic pregnancies accompanied by severe hemoperitoneum.</p> <p><b>Material and methods<i>:</i></b> The main outcome measures were duration of surgery, intraoperative bleeding quantity, complications, post-operative pain scores, additional analgesic requirements, and length of hospital stay.</p> <p><b>Results:</b> A total of 53 women, 28 in the conventional laparoscopy group and 25 in the SILS group, participated in the study. There were no differences in demographic characteristics between the two groups. There were no differences in terms of variables including gestational week, beta human chorionic gonadotropin (βhCG) levels, and operation time. No intraoperative complications were observed in either group. The groups exhibited no significant differences regarding additional analgesic requirements or postoperative pain scores. However, pain at the sixth postoperative hour was lower in the SILS group. This effect was not observed at 12 and 24 hours.</p> <p><b>Conclusion:</b> SILS appears to be effective and safe for the treatment of ruptured ectopic pregnancies accompanied by hemoperitoneum.</p

Harlequin Ichtyosis: A Case Report

Harlequin ichthyosis is a severe and usually fatal congenital keratinization disorder. Although it has many characteristic findings on prenatal ultrasound such as a wide gaping mouth, intrauterine growth retardation, short limbs, joint contractures, edema of the hands and feet and cloudy amniotic fluid, most of the time it is diagnosed at birth. In this case report we summarize a patient who delivered a baby with Harlequin ichthyosis