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    БостояниС ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ полости Ρ€Ρ‚Π° Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с систСмной склСродСрмиСй

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    Systemic sclerosis (SSc) can lead to pathological changes in the maxillofacial region, contributing to the violation of the microbiocenosis of the oral cavity with a predominance of pathogenic microflora.Objective: to study the composition of the oral microflora in patients with SSc. Patients and methods. The composition of the oral microflora was studied in 50 patients with SSc. The control group consisted of 50 subjects without rheumatic diseases. To assess the intensity of dental caries and the level of oral hygiene we used dental indices: the index of caries intensity (Decayed, Missing, and Filled Teeth (DMFT) and the hygienic index (OHI-S).Results and discussion. Microbiological examination in patients with SSc revealed pathogenic Staphylococcus aureus and Candida albicans > 10-6 CFU in equal percentage of cases (18.9%), which was significantly more frequent than in the control group (p=0.049). In the oral cavity in SSc, there were no representatives of normal microflora (lactobacilli). In patients with SSc, the DMFT index was 17.8Β±7.1 on average, and OHI-S – 2.3Β±0.7, which corresponds to a very high level of caries intensity and low indicators of oral hygiene, respectively. When analyzing the microflora of the oral cavity in 90% of cases, a dysbiotic shift of the 3rd degree was stated.Conclusion. It can hypothesized that the qualitative and quantitative composition of the microflora of the oral cavity affects the development and severity of inflammatory and destructive pathology of the periodontal and oral mucosa. It is necessary to develop and implement an adapted personal hygiene regimen, including cleansing of the tongue and administration of local probiotics, which, as part of complex therapy, can improve the results of SSc treatment.БистСмная склСродСрмия (Π‘Π‘Π”) ΠΌΠΎΠΆΠ΅Ρ‚ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ΡŒ ΠΊ патологичСским измСнСниям Π² Ρ‡Π΅Π»ΡŽΡΡ‚Π½ΠΎ-Π»ΠΈΡ†Π΅Π²ΠΎΠΉ области, ΡΠΏΠΎΡΠΎΠ±ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΠΌ Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡŽ ΠΌΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·Π° полости Ρ€Ρ‚Π° с ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°Π½ΠΈΠ΅ΠΌ ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π½ΠΎΠΉ ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹.ЦСль исслСдования – ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ состава ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ полости Ρ€Ρ‚Π° Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π‘Π‘Π”.ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Бостав ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ полости Ρ€Ρ‚Π° исслСдован Ρƒ 50 Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π‘Π‘Π”. ΠšΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒΠ½ΡƒΡŽ Π³Ρ€ΡƒΠΏΠΏΡƒ составили 50 Π»ΠΈΡ† Π±Π΅Π· рСвматичСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ. Для ΠΎΡ†Π΅Π½ΠΊΠΈ интСнсивности кариСса ΠΈ уровня Π³ΠΈΠ³ΠΈΠ΅Π½Ρ‹ полости Ρ€Ρ‚Π° опрСдСляли стоматологичСскиС индСксы: индСкс интСнсивности кариСса (КПУ) ΠΈ гигиСничСский индСкс (OHI-S).Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ обсуТдСниС. ΠŸΡ€ΠΈ микробиологичСском исслСдовании Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… CCΠ” Π² ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²ΠΎΠΌ числС случаСв (18,9%) ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Ρ‹ ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π½Ρ‹ΠΉ Staphylococcus aureus ΠΈ Candida albicans >10β‹…6 ΠšΠžΠ•, Ρ‡Ρ‚ΠΎ Π±Ρ‹Π»ΠΎ Π·Π½Π°Ρ‡ΠΈΠΌΠΎ Ρ‡Π°Ρ‰Π΅, Ρ‡Π΅ΠΌ Π² ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒΠ½ΠΎΠΉ Π³Ρ€ΡƒΠΏΠΏΠ΅ (Ρ€=0,049). Π’ полости Ρ€Ρ‚Π° ΠΏΡ€ΠΈ Π‘Π‘Π” отсутствовали прСдставитСли Π½ΠΎΡ€ΠΌΠ°Π»ΡŒΠ½ΠΎΠΉ ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ (Π»Π°ΠΊΡ‚ΠΎΠ±Π°ΠΊΡ‚Π΅Ρ€ΠΈΠΈ). Π£ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π‘Π‘Π” индСкс КПУ Π² срСднСм составлял 17,8Β±7,1, Π° OHI-S – 2,3Β±0,7, Ρ‡Ρ‚ΠΎ ΡΠΎΠΎΡ‚Π²Π΅Ρ‚ΡΡ‚Π²ΡƒΡŽΡ‚ ΠΎΡ‡Π΅Π½ΡŒ высокому ΡƒΡ€ΠΎΠ²Π½ΡŽ интСнсивности кариСса ΠΈ Π½ΠΈΠ·ΠΊΠΈΠΌ показатСлям Π³ΠΈΠ³ΠΈΠ΅Π½Ρ‹ полости Ρ€Ρ‚Π° соотвСтствСнно. ΠŸΡ€ΠΈ Π°Π½Π°Π»ΠΈΠ·Π΅ ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ полости Ρ€Ρ‚Π° Π² 90% случаСв констатирован дисбиотичСский сдвиг 3-ΠΉ стСпСни.Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. МоТно ΠΏΠΎΠ»Π°Π³Π°Ρ‚ΡŒ, Ρ‡Ρ‚ΠΎ качСствСнный ΠΈ количСствСнный состав ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ полости Ρ€Ρ‚Π° влияСт Π½Π° Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ ΠΈ Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½ΠΎΡΡ‚ΡŒ Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ-дСструктивной ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΠ°Ρ€ΠΎΠ΄ΠΎΠ½Ρ‚Π° ΠΈ слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ Ρ€ΠΎΡ‚ΠΎΠ²ΠΎΠΉ полости. НСобходимы Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ° ΠΈ Π²Π½Π΅Π΄Ρ€Π΅Π½ΠΈΠ΅ Π°Π΄Π°ΠΏΡ‚ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ схСмы ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½ΠΎΠΉ Π³ΠΈΠ³ΠΈΠ΅Π½Ρ‹, Π²ΠΊΠ»ΡŽΡ‡Π°ΡŽΡ‰Π΅ΠΉ чистку языка ΠΈ использованиС мСстных ΠΏΡ€ΠΎΠ±ΠΈΠΎΡ‚ΠΈΠΊΠΎΠ², Ρ‡Ρ‚ΠΎ Π² составС комплСксной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΌΠΎΠΆΠ΅Ρ‚ ΡƒΠ»ΡƒΡ‡ΡˆΠΈΡ‚ΡŒ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ лСчСния Π‘Π‘Π”

    Spectrotemporal similarity and self-imaging of nonlinear dispersive similarition

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    International audienceUsing spectral-interferometry for short pulse complete characterization, we studied the similariton generated in single-mode fiber without gain due to the combined impacts of nonlinearity and dispersion. The nonlinear-spectronic nature of such a similariton, with the key specificity of linear chirping, leads to its self-spectrotemporal imaging, important for applications to signal analysis - synthesis problems in ultrafast optics
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