NMR study of magnetic nanoparticles Ni@C

The 61Ni, 13C NMR spectra of carbon encapsulated nickel nanoparticles have been obtained. It has been shown that the cores of the particles consist of metallic nickel with face-centered cubic structure, nickel carbide Ni3C and carbon-nickel solid solution. The carbon shell of nanoparticles is a highly defective structure and close to an amorphous glassy-like carbon. © Published under licence by IOP Publishing Ltd.Ural Branch, Russian Academy of Sciences, UB RAS: 18-10-2-37.The study was performed within the state assignments of the Mikheev Institute of Metal Physics of the Ural Branch of the Russian Academy of Sciences: state program «Function» No АААА-А19-119012990095-0; state program «Magnit» No АААА-А18-118020290129-5 and state program «Alloys». The research also was supported by the project of the complex program of Ural Branch of Russian Academy of Sciences № 18-10-2-37

Application of NMR for quantification of magnetic nanoparticles and development of paper-based assay

H1 NMR relaxometry is a method that is extremely sensitive to the presence of magnetic nanoparticles, which significantly affect the transverse relaxation time of the water proton. Accordingly, the use of magnetic nanoparticles as labels allows detection of even extremely small amounts of the test substance. This paper analyzes the prospects for applying the method of solid-phase NMR-relaxometric determination of biologically active molecules. The nitrocellulose membranes are chosen as a solid phase and nanoparticles based on iron core with a carbon shell are used as magnetic labels. The possibility of detecting small concentrations of magnetic particles in porous medium is demonstrated. Finally, the ability to detect extremely low concentrations of an analyte, in this case, streptavidin protein (0.5 ng/ml to 100 ng/ml), which is actively used in various fields of biology and medicine, is demonstrated. © Published under licence by IOP Publishing Ltd.Russian Science Foundation, RSF: 17-15-01116The work was carried out within the Russian Science Foundation project 17-15-01116. equipment of the Ural Center for Shared Use Modern nanotechnology UrFU was used