Phosphaannulation by Palladium-Catalyzed Carbonylation of C–H Bonds of Phosphonic and Phosphinic Acids

An efficient phosphaannulation by Pd-catalyzed carbonylation of C–H bonds of phosphonic and phosphinic acids for the synthesis of oxaphosphorinanone oxides is reported. These compounds are novel phosphorus heterocyclic scaffolds, thus opening a new avenue to sequential C–C/C–O bond formation in one pot