Physical condition and spin-resolved exchange correlation kernels in an inhomogeneous many electron system

We first exploit the spin symmetry relation $f^{\rm xc}_{s\bar s} (\zeta)=f^{\rm xc}_{\bar s s}(-\zeta)$ for the exact exchange correlation kernel $f^{\rm xc}_{s\bar s}(\zeta)$ in an inhomogeneous many electron system with arbitrary spin polarization $\zeta$. The physical condition required to satisfy the specific symmetry relation $f^{\rm xc}_{s\bar s}(\zeta) = f^{\rm xc}_{\bar s s}(\zeta)$ is derived and examined for simple ferromagnetic-nonmagnetic structure by taking the electrochemical potential into account. The condition is then applied to several composite systems useful in spintronics applications such as the magnetic system with net spin polarization.Comment: 5 pages, 1 figur

Origin of the Growing Length Scale in M-p-Spin Glass Models

Two versions of the M-p-spin glass model have been studied with the Migdal-Kadanoff renormalization group approximation. The model with p=3 and M=3 has at mean-field level the ideal glass transition at the Kauzmann temperature and at lower temperatures still the Gardner transition to a state like that of an Ising spin glass in a field. The model with p=3 and M=2 has only the Gardner transition. In the dimensions studied, d=2,3 and 4, both models behave almost identically, indicating that the growing correlation length as the temperature is reduced in these models -- the analogue of the point-to-set length scale -- is not due to the mechanism postulated in the random first order transition theory of glasses, but is more like that expected on the analogy of glasses to the Ising spin glass in a field.Comment: 5 pages, 3 figures, revised versio

The Attitudes of Malaysians Towards Soybean Products

This study was carried out to determine the..attitudes ofMalaysians towards soybean products. The goal established for this study was: 'How do Malaysians, represented by a random sample of civil employees, jeel towards having more soybean products in their daily diet?" An attitude survey was administered to 23'0 civil employees in Kuala Lumpur. The survey instrument using the Likert Rating Techniques, had 9 statements. Of the 230 copies sent, 211 were returned. The results pertaining to the highlights of the study are discussed. The major findings reveal significant attitudes towards soybean products. Present attitudes and food habits have been identified. The data shows that Malaysians as represented by civil employees have positive attitudes towards soy bean products

A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2.

BACKGROUND: Variation in an individual\u27s genetic status can impact the development of pancreatic ductal adenocarcinoma; however, the majority of familial pancreatic cancers (FPC) cannot yet be attributed to a specific inherited mutation. We present data suggesting a correlation between loss-of-function single nucleotide polymorphisms (SNPs) in an immune regulator gene, indoleamine-2,3-dioxygenase-2 (IDO2), and an increased risk of FPC. STUDY DESIGN: Germline DNA from patients who underwent resection for pancreatic ductal adenocarcinoma (n = 79) was sequenced for the IDO2 SNPs R248W and Y359Stop. Genotypes resulting in inactivation of IDO2 (Y325X homozygous, R248W homozygous) were labeled as homozygous, and the other genotypes were grouped as wild-type or heterozygous. Genotype distributions of each SNP were analyzed for Hardy-Weinberg deviation. A genotype frequency set from the 1000 Genomes Project (n = 99) was used as a genetic control for genotype distribution comparisons. RESULTS: A significant 2-fold increase in the overall prevalence of the Y359Stop homozygous genotype compared with the expected Hardy-Weinberg equilibrium was noted (p \u3c 0.05). Familial pancreatic cancer was noted in 15 cases (19%) and comparison of the FPC cohort set to the genetic control set showed a 3-fold increase in Y359Stop homozygous rates (p = 0.054). Overall in our cohort, the homozygous genotype group was associated with increased risk of FPC (odds ratio 5.4; 95% CI 1.6 to 17.6; p \u3c 0.01). Sex, age at diagnosis, and history of tobacco use were not found to be significantly associated with FPC. CONCLUSIONS: Our preliminary data suggest a strong association between the IDO2 inactivating Y359Stop SNP and an increased risk of FPC when compared with the control group. Future studies will evaluate the value of IDO2 genotyping as a prognostic, early detection marker for pancreatic ductal adenocarcinoma and a predictive marker for novel immune checkpoint therapies

Francis Daniels Moore: one of the brightest minds in the surgical field.

Francis Daniels Moore was a pioneer ahead of his time who made numerous landmark contributions to the field of surgery, including the understanding of metabolic physiology during surgery, liver and kidney transplant, and the famous Study on Surgical Services of the United States (SOSSUS) report of 1975 that served for decades as a guideline for development of surgical residencies. He was the epitome of what a physician should be, a compassionate and dedicated surgeon, innovative scientist, and a medical professional dedicated to quality medical education across all specialties

John H. Gibbon, Jr., M.D.: surgical innovator, pioneer, and inspiration.

Throughout history there have been many discoveries that have changed the world, including Albert Einstein’s theory of relativity, Alexander Graham Bell’s telephone, and Jack Kilby and Robert Noyce’s microchip. There are a few analogous contributions that have been made in medicine: Sir Alexander’s discovery of penicillin, Lister’s principles of antiseptic technique, Salk and Sabin’s vaccines for polio, as well as numerous others. These innovative thinkers all had two factors in common. First, they were pioneers who faced problems that had no solutions at the time and who refused to accept the status quo in the face of great scrutiny and resistance. Second, their contributions would forever change the world. In 1930, a profound experience with a patient would forever change Dr. John H. Gibbon, Jr. and stimulate an idea to create a device that at the time sounded audacious and impossible. His device would temporarily take the role of both the heart and lungs to make repairs inside the heart or the great vessels. Twentythree years later, Dr. Gibbon used his machine to perform the first successful bypass-assisted open heart surgery

Ground state energy of qq-state Potts model: the minimum modularity

A wide range of interacting systems can be described by complex networks. A common feature of such networks is that they consist of several communities or modules, the degree of which may quantified as the \emph{modularity}. However, even a random uncorrelated network, which has no obvious modular structure, has a finite modularity due to the quenched disorder. For this reason, the modularity of a given network is meaningful only when it is compared with that of a randomized network with the same degree distribution. In this context, it is important to calculate the modularity of a random uncorrelated network with an arbitrary degree distribution. The modularity of a random network has been calculated [Phys. Rev. E \textbf{76}, 015102 (2007)]; however, this was limited to the case whereby the network was assumed to have only two communities, and it is evident that the modularity should be calculated in general with $q(\geq 2)$ communities. Here, we calculate the modularity for $q$ communities by evaluating the ground state energy of the $q$-state Potts Hamiltonian, based on replica symmetric solutions assuming that the mean degree is large. We found that the modularity is proportional to $\langle \sqrt{k} \rangle / \langle k \rangle$ regardless of $q$ and that only the coefficient depends on $q$. In particular, when the degree distribution follows a power law, the modularity is proportional to $\langle k \rangle^{-1/2}$. Our analytical results are confirmed by comparison with numerical simulations. Therefore, our results can be used as reference values for real-world networks.Comment: 14 pages, 4 figure