Countermeasure of Research University Development Based on the Index System Analysis of the Comprehensive Competitiveness Ranking of Chinese Universities

Under new situations and circumstances, more quickly and efficiently resources allocation is a natural advance for higher education development. Its inevitable result is that universities must pay great attention to the construction and the promotion of their competitiveness hand in hand with cultivating talents needed in society. This paper made a comprehensive overview to the Comprehensive Competitiveness Ranking of Chinese Universities (CCRCU) released by RCCSE, and emphasized on analyzing the changing trends of evaluation methods and indicators, and digging the development trends of the connotation and extension of universities competence. Some suggestions and countermeasures are put forward

THE CORRELATIONS BETWEEN DYNAMIC WALKING STABILITY AND PERCEPTION-MOTOR ABILITIES OF HUMANS

External perturbations can challenge a person’s walking stability, and people will autonomously make a series of responses to regain the balance of walking, which includes two periods: perturbation-perception (reaction time, RT) and posture-adjustment (motion time, MT). The purpose of this paper was to investigate the correlations between the dynamic walking stability and perception-motor abilities. During the 30 level walking trials preformed by sixteen healthy participants, perturbations were applied at random. The fall probability (FP) during the walking with perturbations was calculated to evaluate the dynamic walking stability of each participant. Furthermore, the ground reaction force (GRF) of each participant during walking with perturbations was recorded and analyzed. The experimental results show that the RT had a significant positive-correlation with FP, while MT had no correlation with FP

Federal Recovery Funds Allocated

Figure S1. Overview of the informatics pipeline used to the identify lincRNAs in goat. (PDF 216 kb

Ticagrelor vs Clopidogrel in CYP2C19 loss-of-function carriers with Stroke or TIA

BACKGROUNDComparisons between ticagrelor- aspirin and clopidogrel-aspirin in CYP2C19 loss-of-function carriers have not been well studied for secondary stroke prevention.METHODSWe conducted a randomized, double-blind, placebo-controlled trial of 6,412 patients with a minor ischemic stroke or TIA who carried CYP2C19 LOF alleles determined by point-of-care testing. Patients were randomly assigned within 24 hours after symptom onset, in a 1:1 ratio to receive ticagrelor (180 mg loading dose on day 1 followed by 90 mg twice daily for days 2 through 90) or clopidogrel (300 mg loading dose on day 1 followed by 75 mg per day for days 2 through 90), plus aspirin (75-300 mg loading dose followed by 75 mg daily for 21 days). The primary efficacy outcome was stroke and the primary safety outcome was severe or moderate bleeding, both within 90 days. RESULTSStroke occurred within 90 days in 191 (6.0%) versus 243 (7.6%), respectively (hazard ratio, 0.77; 95% confidence interval, 0.64 to 0.94; P=0.008). Moderate or severe bleeding occurred in 9 patients (0.3%) in the ticagrelor-aspirin group and in 11 patients (0.3%) in the clopidogrel-aspirin group; any bleeding event occurred in 170 patients (5.3%) vs 80 (2.5%), respectively. CONCLUSIONSAmong Chinese patients with minor ischemic stroke or TIA within 24 hours after symptoms onset who were carriers of CYP2C19 loss-of-function alleles, ticagrelor- aspirin was modestly better than clopidogrel-aspirin for reducing the risk of stroke but was associated with more total bleeding events at 90 days. (CHANCE-2 ClinicalTrials.gov number, NCT04078737.

Characterization of human alveolar osteoblasts in two- dimensional and three-dimensional cultures

Ph.DDOCTOR OF PHILOSOPH

Engineering tubular bone constructs

Cell-sheet techniques have been proven effective in various soft tissue engineering applications. In this experiment, we investigated the feasibility of bone tissue engineering using a hybrid of mesenchymal stem cell (MSC) sheets and PLGA meshes. Porcine MSCs were cultured to a thin layer of cell sheets via osteogenic induction. Tube-like long bones were constructed by wrapping the cell sheet on to PLGA meshes resulting in constructs which could be cultured in spinner flasks, prior to implantation in nude rats. Our results showed that the sheets were composed of viable cells and dense matrix with a thickness of about 80–120 mm, mineral deposition was also observed in the sheet. In vitro cultures demonstrated calcified cartilage-like tissue formation and most PLGA meshes were absorbed during the 8-week culture period. In vivo experiments revealed that dense mineralized tissue was formed in subcutaneous sites and the 8- week plants shared similar micro-CT characteristics with native bone. The neo tissue demonstrated histological markers for both bone and cartilage, indicating that the bone formation pathway in constructs was akin to endochondral ossification, with the residues of PLGA having an effect on the neo tissue organization and formation. These results indicate that cell-sheet approaches in combination with custom-shaped scaffolds have potential in producing bone tissue

Subwavelength imaging designed with meander-line anisotropic epsilon-near-zero (AENZ) metamaterial structures

Subwavelength imaging is designed and demonstrated utilizing practical meander-line metamaterial structures in this work. By carefully designing the composite structure, desirable anisotropic epsilon-near-zero (AENZ) index is obtained. To verify the imaging performance, a 3D model is constructed which is composed of period meander-line elements in numerical validation. Imaging in super resolution is observed. We remark that in the model, both of natural material loss and finite element size effect are considered mimicking practical scenarios. The demonstration results are convincing and helpful to provide practical insights for future applications of subwavelength imaging in microwave frequency range