39,888 research outputs found
Pressure Dependence of Wall Relaxation in Polarized He Gaseous Cells
We have observed a linear pressure dependence of longitudinal relaxation time
() at 4.2 K and 295 K in gaseous He cells made of either bare pyrex
glass or Cs/Rb-coated pyrex due to paramagnetic sites in the cell wall. The
paramagnetic wall relaxation is previously thought to be independent of He
pressure. We develop a model to interpret the observed wall relaxation by
taking into account the diffusion process, and our model gives a good
description of the data
Precision spectroscopy and density-dependent frequency shifts in ultracold Sr
By varying the density of an ultracold Sr sample from cm
to cm, we make the first definitive measurement of the
density-related frequency shift and linewidth broadening of the -
optical clock transition in an alkaline earth system. In addition, we
report the most accurate measurement to date of the Sr
optical clock transition frequency. Including a detailed analysis of systematic
errors, the frequency is () Hz.Comment: 4 pages, 4 figures, 1 table. submitte
Magnetic Interaction in the Geometrically Frustrated Triangular Lattice Antiferromagnet
The spin wave excitations of the geometrically frustrated triangular lattice
antiferromagnet (TLA) have been measured using high resolution
inelastic neutron scattering. Antiferromagnetic interactions up to third
nearest neighbors in the ab plane (J_1, J_2, J_3, with
and ), as well as out-of-plane coupling (J_z, with
) are required to describe the spin wave dispersion
relations, indicating a three dimensional character of the magnetic
interactions. Two energy dips in the spin wave dispersion occur at the
incommensurate wavevectors associated with multiferroic phase, and can be
interpreted as dynamic precursors to the magnetoelectric behavior in this
system.Comment: 4 pages, 4 figures, published in Phys. Rev. Let
A de Bruijn graph approach to the quantification of closely-related genomes in a microbial community
The wide applications of next-generation sequencing (NGS) technologies in metagenomics have raised many computational challenges. One of the essential problems in metagenomics is to estimate the taxonomic composition of a microbial community, which can be approached by mapping shotgun reads acquired from the community to previously characterized microbial genomes followed by quantity profiling of these species based on the number of mapped reads. This procedure, however, is not as trivial as it appears at first glance. A shotgun metagenomic dataset often contains DNA sequences from many closely-related microbial species (e.g., within the same genus) or strains (e.g., within the same species), thus it is often difficult to determine which species/strain a specific read is sampled from when it can be mapped to a common region shared by multiple genomes at high similarity. Furthermore, high genomic variations are observed among individual genomes within the same species, which are difficult to be differentiated from the inter-species variations during reads mapping. To address these issues, a commonly used approach is to quantify taxonomic distribution only at the genus level, based on the reads mapped to all species belonging to the same genus; alternatively, reads are mapped to a set of representative genomes, each selected to represent a different genus. Here, we introduce a novel approach to the quantity estimation of closely-related species within the same genus by mapping the reads to their genomes represented by a de Bruijn graph, in which the common genomic regions among them are collapsed. Using simulated and real metagenomic datasets, we show the de Bruijn graph approach has several advantages over existing methods, including (1) it avoids redundant mapping of shotgun reads to multiple copies of the common regions in different genomes, and (2) it leads to more accurate quantification for the closely-related species (and even for strains within the same species)
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