A lean man with nonalcoholic fatty liver disease

ArticleCLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 5(3): XXXII (2007)journal articl

Quark-meson coupling model with constituent quarks: Exchange and pionic effects

The binding energy of nuclear matter including exchange and pionic effects is calculated in a quark-meson coupling model with massive constituent quarks. As in the case with elementary nucleons in QHD, exchange effects are repulsive. However, the coupling of the mesons directly to the quarks in the nucleons introduces a new effect on the exchange energies that provides an extra repulsive contribution to the binding energy. Pionic effects are not small. Implications of such effects on observables are discussed.Comment: 12 pages, latex, 1 figure, to appear in Phys. Lett.

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model.

Pancreatic cancer is a highly lethal disease in part due to incomplete tumor resection. Targeting by tumor-specific antibodies conjugated with a fluorescent label can result in selective labeling of cancer in vivo for surgical navigation. In the present study, we describe a patient-derived orthotopic xenograft model of pancreatic cancer that recapitulated the disease on a gross and microscopic level, along with physiologic clinical manifestations. We additionally show that the use of an anti-CEA antibody conjugated to the near-infrared (NIR) fluorescent dye, IRDye800CW, can selectively highlight the pancreatic cancer and its metastases in this model with a tumor-to-background ratio of 3.5 (SEM 0.9). The present results demonstrate the clinical potential of this labeling technique for fluorescence-guided surgery of pancreatic cancer

H-Dihyperon in Quark Cluster Model

The H dihyperon (DH) is studied in the framework of the SU(3) chiral quark model. It is shown that except the $\sigma$ chiral field, the overall effect of the other SU(3) chiral fields is destructive in forming a stable DH. The resultant mass of DH in a three coupled channel calculation is ranged from 2225 $MeV$ to 2234 $MeV$.Comment: 9 pages, emte

Possible ΔΔ\Delta\Delta dibaryons in the quark cluster model

In the framework of RGM, the binding energy of one channel $\Delta\Delta_{(3,0)}$($d^*$) and $\Delta\Delta_{(0,3)}$ are studied in the chiral SU(3) quark cluster model. It is shown that the binding energies of the systems are a few tens of MeV. The behavior of the chiral field is also investigated by comparing the results with those in the SU(2) and the extended SU(2) chiral quark models. It is found that the symmetry property of the $\Delta\Delta$ system makes the contribution of the relative kinetic energy operator between two clusters attractive. This is very beneficial for forming the bound dibaryon. Meanwhile the chiral-quark field coupling also plays a very important role on binding. The S-wave phase shifts and the corresponding scattering lengths of the systems are also given.Comment: LeTex with 2 ps figure

Deltaron Dibaryon Structure in Chiral SU(3) Quark Model

We discuss the structure of Deltaron dibaryon in the chiral SU(3) quark model. The energy of Deltaron is obtained by considering the coupling of the $\Delta\Delta$ and $CC$ (hidden color) channels. The effects of various parameters on the Deltaron mass are also studied. It is shown that the mass of Deltaron is lower than the mass of $\Delta\Delta$ but higher than the mass of $\Delta N \pi$.Comment: 15 pages, Late

Deformed Base Antisymmetrized Molecular Dynamics and its Application to ^{20}Ne

A new theoretical framework named as deformed base antisymmetrized molecular dynamics that uses the localized triaxially deformed Gaussian as the single particle wave packet is presented. The model space enables us to describe sufficiently well the deformed mean-field structure as well as the cluster structure and their mixed structure within the same framework. The improvement over the original version of the antisymmetrized molecular dynamics which uses the spherical Gaussian is verified by the application to $^{20}{\rm Ne}$ nucleus. The almost pure $\alpha + ^{16}{\rm O_{g.s}}$ cluster structure of the $K^\pi$=$0^-$ band, the distortion of the cluster structure in the $K^\pi$=$0^+_1$ band and the dominance of the deformed mean-field structure of the $K^\pi$=$2^-$ band are confirmed and their observed properties are reproduced. Especially, the intra-band E2 transition probabilities in $K^\pi$=$0^+_1$ and $2^-$ bands are reproduced without any effective charge. Since it has been long known that the pure $\alpha + ^{16}{\rm O}_{g.s.}$ cluster model underestimates the intra-band $E2$ transitions in the $K^\pi$=$0^+_1$ band by about 30%, we consider that this success is due to the sufficient description of the deformed mean-field structure in addition to the cluster structure by the present framework. From the successful description of $^{20}{\rm Ne}$, we expect that the present framework presents us with a powerful approach for the study of the coexistence and interplay of the mean-field structure and the cluster structure