Symmetry and Integrability of Non-Singlet Sectors in Matrix Quantum Mechanics

We study the non-singlet sectors of matrix quantum mechanics (MQM) through an operator algebra which generates the spectrum. The algebra is a nonlinear extension of the W_\infty algebra where the nonlinearity comes from the angular part of the matrix which can not be neglected in the non-singlet sector. The algebra contains an infinite set of commuting generators which can be regarded as the conserved currents of MQM. We derive the spectrum and the eigenfunctions of these conserved quantities by a group theoretical method. An interesting feature of the spectrum of these charges in the non-singlet sectors is that they are identical to those of the singlet sector except for the multiplicities. We also derive the explicit form of these commuting charges in terms of the eigenvalues of the matrix and show that the interaction terms which are typical in Calogero-Sutherland system appear. Finally we discuss the bosonization and rewrite the commuting charges in terms of a free boson together with a finite number of extra degrees of freedom for the non-singlet sectors.Comment: 34 pages, 4 figure

Extensive ablation for persistent atrial fibrillation patients with mitral regurgitation: Insights from the EARNEST-PVI prospective randomized trial

Sunaga A., Matsuoka Y., Nakatani D., et al. Extensive ablation for persistent atrial fibrillation patients with mitral regurgitation: Insights from the EARNEST-PVI prospective randomized trial. International Journal of Cardiology 410, 132231 (2024); https://doi.org/10.1016/j.ijcard.2024.132231.Background: Extensive ablation in addition to pulmonary vein isolation (PVI) in patients with persistent atrial fibrillation (AF) has not yielded consistent results, indicating diversity in their efficacy. Mitral regurgitation (MR) associated with AF may indicate a higher prevalence of arrhythmogenic substrate, suggesting potential benefits of extensive ablation for these patients. Methods: This post-hoc analysis of the EARNEST-PVI trial compared PVI alone versus an extensive ablation strategy (PVI-plus) in persistent AF patients, stratified by MR presence. The primary endpoint of the study was the recurrence of AF. The secondary endpoints included death, cerebral infarction, and procedure-related complications. Results: The trial included 495 eligible patients divided into MR and non-MR groups. The MR group consisted of 192 patients (89 in the PVI-alone arm and 103 in the PVI-plus arm), while the non-MR group had 303 patients (158 in the PVI-alone arm and 145 in the PVI-plus arm). In the non-MR group, recurrence rates were similar between PVI-alone and PVI-plus arms (Log-rank P = 0.47, Hazard ratio = 0.85 [95%CI: 0.54–1.33], P = 0.472). However, in the MR group, PVI-plus was significantly more effective in preventing AF recurrence (Log-rank P = 0.0014, Hazard ratio = 0.40 [95%CI: 0.22–0.72], P = 0.0021). No significant differences were observed in secondary endpoints between the two arms. Conclusions: For persistent AF patients with mild or greater MR, receiving PVI-plus was superior to PVI-alone in preventing AF recurrence. Conversely, for patients without MR, the effectiveness of extensive ablation was not demonstrated. These findings suggest tailoring ablation strategies based on MR presence can lead to better outcomes in AF management

パネル トーク タブンカ シャカイ ニ モトメ ラレル ジンザイ トワ パネル トーク タブンカ シャカイ ニ モトメ ラレル ジンザイ トワ タブンカ シャカイ コーディネーター ヨウセイ プログラム ソノ センモンセイ ト リキリョウ ケイセイ ノ トリクミ

Membrane-based liquid desiccant dehumidification has attracted increasing interests with elimination of solution droplets carryover problem. In this study, a membrane-based hybrid liquid desiccant dehumidification cooling system is developed, which is mainly composed of a dehumidifier, a regenerator and an evaporative cooler. The system is capable to remove latent load by the liquid desiccant dehumidification unit and simultaneously to handle sensible load with an evaporative cooling unit. This paper presents a performance evaluation study of the hybrid system with calcium chloride as liquid desiccant based on experimental data. Series of tests are conducted to identify influences of operating variables and conditions (i.e. desiccant solution concentration ratio, regeneration temperature, inlet air condition, etc.) on the system performance. The experimental results indicate that the system is viable for dehumidification cooling purpose. Furthermore, it is noteworthy that mass balance between the dehumidifier and regenerator should be achieved for system steady operation. Thermal COPth of 0.70 and 24 electrical COPel of 2.62 are achieved respectively under steady operating condition at CaCl2 concentration ratio of 36%