SNOWMASS WHITE PAPER - SLHC Endcap 1.4<y<4 Hadron Optical Calorimetry Upgrades in CMS with Applications to NLC/T-LEP, Intensity Frontier, and Beyond

Radiation damage in the plastic scintillator and/or readout WLS fibers in the HE endcap calorimeter 1.4<y<4 in the CMS experiment at LHC and SLHC will require remediation after 2018. We describe one alternative using the existing brass absorber in the Endcap calorimeter, to replace the plastic scintillator tiles with BaF2 tiles, or quartz tiles coated with thin(1-5 micron) films of radiation-hard pTerphenyl(pTP) or the fast phosphor ZnO:Ga. These tiles would be read-out by easily replaceable arrays of straight, parallel WLS fibers coupled to clear plastic-cladded quartz fibers of proven radiation resistance. We describe a second alternative with a new absorber matrix extending to 1.4<y<4 in a novel Analog Particle Flow Cerenkov Compensated Calorimeter, using a dual readout of quartz tiles and scintillating (plastic, BaF2, or pTP/ ZnO:Ga thin film coated quartz, or liquid scintillator) tiles, also using easily replaceable arrays of parallel WLS fibers coupled to clear quartz transmitting fibers for readout. An Analog Particle Flow Scintillator-Cerenkov Compensated Calorimeter has application in NLC/T-LEP detectors and Intensity Frontier detectors

Relationship between antihypertensive medications and cognitive impairment: Part II. Review of Physiology and animal studies

Purpose of Review There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHM) and dementia risk are less clear. An increased interest in AHM has resulted in expanding publications; however, none of the recent reviews provide comprehensive review. Our extensive review includes 24 mechanistic animal and human studies published over the last 5 years assessing relationship between AHM and cognitive function. Recent Findings All classes of AHM showed similar result patterns in animal studies. The mechanism by which AHM exert their effect was extensively studied by evaluating well-established pathways of AD disease process, including amyloid beta (Aβ), vascular, oxidative stress and inflammation pathways, but only few studies evaluated the blood pressure lowering effect on the AD disease process. Summary Methodological limitations of the studies prevent comprehensive conclusions prior to further work evaluating AHM in animals and larger human observational studies, and selecting those with promising results for future RCTs

Snowmass White Paper CMS Upgrade: Forward Lepton-Photon System

This White Paper outlines a proposal for an upgraded forward region to extend CMS lepton (e, mu) and photon physics reach out to 2.2<eta<5 for LHC and SLHC, which also provides better performance for the existing or new forward hadron calorimetry for jet energy and (eta, phi) measurements, especially under pileup/overlaps at high lumi, as LHC luminosity, energy and radiation damage increases

Relationship between antihypertensive medications and cognitive impairment: Part I. review of human studies and clinical trials

Purpose of review: There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHMs) and dementia risk are less consistent. An increased interest in AHM has resulted in expanding publications; however, none of the recent reviews are comprehensive. Our extensive review includes 15 observational and randomized controlled trials (RCTs) published over the last 5 years, assessing the relationship between AHM and cognitive impairment. Recent findings: All classes of AHM showed similar result patterns in human studies with the majority of study results reporting point estimates below one and only a small number of studies (N = 15) reporting statistically significant results in favor of a specific class. Summary: Only a small number of studies reported statistically significant results in favor of a specific class of AHM. Methodological limitations of the studies prevent definitive conclusions. Further work is now needed to evaluate the class of AHM and cognitive outcomes in future RCTs, with a particular focus on the drugs with the promising results in both animals and human observational studies

The Hopf algebra structure of the Z3_3-graded quantum supergroup GLq,j(1∣1)_{q,j}(1|1)

In this work, we give some features of the Z$_3$-graded quantum supergroup

MAT-759: PARTICLE SIZE ANALYSIS AS A MEANS TO BETTER UNDERSTAND THE INFLUENCE OF FLY ASH VARIABILITY IN CONCRETE

Fly ash is generated from thermal power stations as an industrial by-product of coal combustion materials. Its particles are generally glassy, spherical in shape, and typically range in size from 0.5-300 µm. Coal fly ash is widely used as a partial cementitious material in concrete, which not only offers economic and environmental benefits but also improves concrete performance. However, variability of the physical description and chemical composition of fly ash has been considered to be a major barrier to its increased use in cement and concrete. In this study the variability and properties of fly ash are characterized with an emphasis on particle size analysis as a means for fly ash producers to better understand material properties in relation to the process of production, classification, and potential modes of utilization. Fly ash samples were collected from different coal-fired power plants from certain Indian and Canadian sources. The particle size analysis results using Laser Diffraction Technique showed a wide variation between the particle size distributions of the studied sources. However, no correlation between the varied size distributions and chemical compositions of fly ash samples was found. Laboratory experiments on the selected fly ash samples are being undertaken to correlate fly ash characteristics and their effects on the performance of concrete mixtures with cementitious replacement level up to 50%

Intravenous self‐administration studies with l ‐deprenyl (selegiline) in monkeys *

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110034/1/cptclpt1994208.pd