SIMULTANEOUS INFRARENAL AORTIC PROSTHESIS IMPLANTATION AND RENAL TRANSPLANTATION IN PATIENT ON PERITONEAL DIALYSIS

SIMULTANEOUS INFRARENAL AORTIC PROSTHESIS IMPLANTATION AND RENAL TRANSPLANTATION IN PATIENT ON PERITONEAL DIALYSI

ПЕРВЫЙ ОПЫТ СИМУЛЬТАННОГО ПРОТЕЗИРОВАНИЯ ИНФРАРЕНАЛЬНОЙ АОРТЫ ПРИ ЕЕ АНЕВРИЗМЕ И АЛЛОТРАНСПЛАНТАЦИИ ТРУПНОЙ ПОЧКИ У ПАЦИЕНТА, НАХОДЯЩЕГОСЯ НА ПЕРИТОНЕАЛЬНОМ ДИАЛИЗЕ

SIMULTANEOUS INFRARENAL AORTIC PROSTHESIS IMPLANTATION AND RENAL TRANSPLANTATION IN PATIENT ON PERITONEAL DIALYSIS ПЕРВЫЙ ОПЫТ СИМУЛЬТАННОГО ПРОТЕЗИРОВАНИЯ ИНФРАРЕНАЛЬНОЙ АОРТЫ ПРИ ЕЕ АНЕВРИЗМЕ И АЛЛОТРАНСПЛАНТАЦИИ ТРУПНОЙ ПОЧКИ У ПАЦИЕНТА, НАХОДЯЩЕГОСЯ НА ПЕРИТОНЕАЛЬНОМ ДИАЛИЗ

Features of the Restoration of Arterial Circulation in Liver Transplantation

Objectives. Violations of tissue blood supply remain one of the most serious complications after liver transplantation. Design. To improve the surgical technique of performing reconstructive interventions on the arteries of the donor and the recipient in order to reduce the frequency of its thrombosis after liver transplantation. We studied 25 donors, 20 men and 5 women, the mean age was 56± 4 years, eighteen of them had left aberrant supplementary artery, which in fifteen departed from the left gastric artery and in three from the aorta above the ventricular stem. Seventeen had the right aberrant artery moving away from the upper mesenteric artery. Twenty recipients with liver cirrhosis (eleven with primary biliary cirrhosis, five with primary sclerosing cholangitis, five with viral etiology C cirrhosis, and three of the lower cirrhosis-cirrhosis disseminated within the Milan criteria. All recipients had standard anatomical branching of the arteries of the liver. The average age was 50±6. All recipients had standard anatomical branching of the liver arteries. Patients underwent liver transplantation with new methods of reconstructive interventions on the donor and recipient arteries. The developed technique provides the shortest pathway of the recipient's arterial blood to the liver transplant, through the superior mesenteric artery provides an alternative source of arterial blood supply from the aorta in which this transplant additionally needs. Presented method of blood circulation restoration at liver transplantation at abnormal structure of arterial channel of the liver transplant is performed inside the recipient's abdominal cavity. At first, blood flow is restored along the reconstructed common hepatic artery, after the right or left aberrant arteries liver transplant. Such technique provides the shortest route of the recipient's arterial blood to the liver transplant, through the upper mesenteric artery provides an alternative source of arterial blood supply from the aorta for which the transplant is additionally needed. This new method of blood circulation restoration provides an opportunity to avoid the formation of "kinking" syndrome, in the occurrence of which the blood vessels are lengthened, the angulation and location of the blood vessel in relation to the grafts and other abdominal organs. This reduces the risk of thrombosis of the arteries of the transplanted liver

ОРГАННОЕ ДОНОРСТВО И ТРАНСПЛАНТАЦИОННАЯ КООРДИНАЦИЯ В САМАРСКОЙ ОБЛАСТИ: ОСОБЕННОСТИ РЕГИОНАЛЬНОЙ МОДЕЛИ

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Long-term therapy of Kaposi’s sarcoma with the use of prospidium chloride and mTOR receptor inhibitors in а patient after kidney transplantation

A case of a long-term management of a patient with Kaposi’s sarcoma developed as presumably related to a “standard” immunosuppressive therapy after kidney transplantation has been described. Immunosuppressive therapy conversion to mTOR receptor inhibitors and administering chemotherapy with prospidium chloride allowed for a long-term remission of the disease and a satisfactory clinical outcome

An acute episode of rhabdomyolysis associated with everolimus and cabergoline intake in a postpartum kidney recipient

Kidney transplantation is one of the most promising ways to ensure the onset and successful maintenance of pregnancy in patients with end-stage chronic renal disease. A multicomponent drug therapy in such patients creates risks for fetal development, primarily due to the teratogenicity of mTOR receptor inhibitors and mycophenolate. Moreover, the inhibitors of the proliferative signal may have potential drug interactions, which can result in additional complications.Rhabdomyolysis is one of them. The paper describes the clinical case of an acute episode of reversible rhabdomyolysis in a patient on everolimus therapy

Disseminated lung tuberculosis and tuberculosis meningoencephalitis after kidney transplantation

The epidemiological situation with tuberculosis in Russia continues to be strained. The issues of accurate diagnosis and treatment remain unsolved; these issues are particularly urgent for the patients after solid organ transplantation because of a higher risk of the disease development while on drug immunosuppression. This article has described the clinical case of a patient with a clinical presentation of disseminated pulmonary tuberculosis that emerged in a steroidresistant rejection. The issues of drug therapy and drug interactions with anti-tuberculosis and immunosuppressive agents have been discussed

New challenges to infectious safety in the implementation of medical activities related to organ and tissue donation for transplantation

Changes in current scientific literature and regulatory documents related to the issues of infectious safety in organ and tissue donation have been analyzed. The suggestions have been given for changing the existing practices to meet new challenges. Data on threats to the safety of organ and tissue donation associated with the COVID-19 pandemic have been presented