7,378 research outputs found
Comparison Between Genetic Algorithm and Electromagnetism-Like Algorithm for Solving Inverse Kinematics
A comparison study between Electromagnetism-Like Algorithm (EM) and Genetic Algorithm (GA)has been presented in this work to solve the Inverse Kinematics (IK) of a four-link planar robot manipulator. The comparison is focused on some points for both algorithms like the accuracy of the results and the speed of convergence. Different target points have been taken to check the performance of each algorithm to solve the IK problem. The results showed that EM algorithm needs less population size and number of generations to get the true solution. There are multiple robot configurations at the goal points and both algorithms are able to find these solutions at each point. Self developed software simulator is used to display some of these solutions at each goal position
A Comparative Analysis of Various Chaotic Genetic Algorithms for Multimodal Function Optimization
This study proposes a novel method of introducing chaotic induced genes into Genetic Algorithms (GA) in order to solve unimodal and multimodal mathematical test functions. The integration of chaotic elements based on logistic map into GA has significantly improved the accuracy in the aspect of the best fitness value. Simulation results show that the influence of Chaos theory does improve the optimization accuracy of the mathematical functions used
An Adaptive Immune Algorithm based Gravimetric Fluid Dispensing Machine
A dispensing system is used in a materials-mixing plant to provide accurate blend ratios
in producing the desired end-use product. The AIS-based (Artificial Immune Systems) fine tuning of
dispensing parameters is proposed by optimizing the components of dispensing time and stopping
time delay to obtain constant and accurate reading from the precision balance scale. Based on the
new dispensing sequence, experimental tests had been carried out using different materials with
varying viscosities. The results indicate that the combination of both PWM and AIS techniques
would minimize overshoot while exhibiting lower steady-state error and faster response time. These
are important in order to overcome the limitations of the conventional volumetric dispensing and
manual parameter tuning presently applied in the dispensing system used in the coatings industry
Mass production of Penaeus monodon Fabricius juveniles in earthen nursery ponds
Different culture techniques were tried for rearing larvae of Penaeus monodon, in order to obtain preliminary data on stocking density, water management, fertilization versus feeding and effect of different types of vertical substrate. The results of the experiments showed that: (1) older fry have greater chances of survival; (2) the traditional nursery pond designs and practices used for milkfish in the Philippines are applicable to prawn only at very low densities and give acceptable high survival rates only when used with the older postlarval stage
Preliminary studies on the holding of live mussels after harvest
Green mussel (Perna viridis) were harvested to study the applicability of chilling to keep the mussels alive for a longer period of time and to review existing methods of packaging and transport. Data obtained from preliminary studies indicated the effectiveness of keeping mussels alive as long as 4 days with minimal mortality rates
Is the high cu tolerance of trichoderma atroviride isolated from the cu-polluted sediment due to adaptation?: an in vitro toxicological study
The tolerance of Cu by Trichoderma atroviride, a tolerant fungus isolated from the drainage surface sediment of the Serdang Industrial Area was investigated under in vitro conditions. Only this fungus species can tolerate up to 600 mg/L of Cu on solid medium Potato Dextrose Agar based on the isolation of the most tolerant fungus from the polluted sediment. Toxicity test performed on T. atroviride, showed a maximum tolerance at 300 mg/L of Cu concentration when grown in liquid medium Potato Dextrose Broth (PDB). The EC50 value of the isolate was 287.73 mg/L of Cu concentration in PDB. The Cu concentration in the drainage surface sediment, where the T. atroviride was isolated from, was 347.64 μg/g while the geochemical distributions of the non-resistant and resistant fractions of Cu were 99.6 and 0.4%, respectively. The sediment data indicated that the drainage had greatly received anthropogenic Cu from the nearby industries which are involved in the manufacturing of plastics and electronic products. The present findings indicate that the high Cu tolerance showed by T. atroviride could be due to the well adaptation of the fungus to the Cu polluted sediment. Therefore, T. atroviride could be a potential bioremediator of Cu pollution in the freshwater ecosystem
Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy
BACKGROUND and AIMS: Hepatitis C virus (HCV) infection has been associated with intravenous (IV) immunoglobulin (Ig), and plasma donations used to prepare IV Ig are now screened to prevent transmission. Thirty-six patients from the United Kingdom received infusions from a batch of anti-HCV antibody-screened intravenous Ig (Gammagard; Baxter Healthcare Ltd., Thetford, Norfolk, England) that was associated with reports of acute hepatitis C outbreak in Europe. The aim of this study was to document the epidemiology of this outbreak. METHODS: Forty-six patients from the United Kingdom treated with Gammagard (34 exposed and 12 unexposed to the batch) returned epidemiological questionnaires. RESULTS: Eighty-two percent of the exposed patients (28 of 34) became positive for HCV RNA. Eighteen percent of the patients (6 of 34) who had infusions with this batch tested negative for HCV RNA, but 2 of the patients had abnormal liver function and subsequently seroconverted to anti-HCV antibody positive. Twenty-seven percent of the patients (9 of 34) developed jaundice, and 79% (27 of 34) had abnormal liver transferase levels. Virus isolates (n=21), including an isolate from the implicated batch, were genotype 1a and virtually identical by sequence analysis of the NS5 region, consistent with transmission from a single source. CONCLUSIONS: Hepatitis C infection can be transmitted by anti-HCV-screened IV Ig. Careful documentation of IV Ig batch numbers and regular biochemical monitoring is recommended for all IV Ig recipients
Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV):use of type-specific peptides to serologically differentiate infections with HCV types 1, 2, and 3
The effect of sequence variability between different types of hepatitis C virus (HCV) on the antigenicity of the NS-4 protein was investigated by epitope mapping and by enzyme-linked immunosorbent assay with branched oligopeptides. Epitope mapping of the region between amino acid residues 1679 and 1768 in the HCV polyprotein revealed two major antigenic regions (1961 to 1708 and 1710 to 1728) that were recognized by antibody elicited upon natural infection of HCV. The antigenic regions were highly variable between variants of HCV, with only 50 to 60% amino acid sequence similarity between types 1, 2, and 3. Although limited serological cross-reactivity between HCV types was detected between peptides, particularly in the first antigenic region of NS-4, type-specific reactivity formed the principal component of the natural humoral immune response to NS-4. Type-specific antibody to particular HCV types was detected in 89% of the samples from anti-HCV-positive blood donors and correlated almost exactly with genotypic analysis of HCV sequences amplified from the samples by polymerase chain reaction. Whereas almost all blood donors appeared to be infected with a single virus type (97%), a higher proportion of samples (40%) from hemophiliacs infected from transfusion of non-heat-inactivated clotting factor contained antibody to two or even all three HCV types, providing evidence that long-term exposure may lead to multiple infection with different variants of HCV
Is the high Cu tolerance of Trichoderma atroviride isolated from the Cu-polluted sediment due to adaptation? an in vitro toxicological study
The tolerance of Cu by Trichoderma atroviride, a tolerant fungus isolated from the drainage surface sediment of the
Serdang Industrial Area was investigated under in vitro
conditions. Only this fungus species can tolerate up to 600 mg/L of Cu on solid medium Potato Dextrose Agar based on the isolation of the most tolerant fungus from the polluted sediment.Toxicity test performed on T. atroviride, showed a maximum tolerance at 300 mg/L of Cu concentration when grown in liquid medium Potato Dextrose Broth (PDB). The EC
50 value of the isolate was 287.73 mg/L of Cu concentration in PDB.The Cu concentration in the drainage surface sediment, where the T. atroviridewas isolated from, was 347.64 μg/g while the geochemical distributions of the non-resistant and resistant fractions of Cu were 99.6 and 0.4%, respectively. The sediment data indicated that the drainage had greatly received anthropogenic Cu from the nearby industries which are involved in the manufacturing of plastics and electronic products. The present findings indicate that the high Cu tolerance showed by T. atroviride
could be due to the well adaptation of the fungus to the Cu polluted sediment. Therefore, T. atroviride could be a potential bioremediator of Cu pollution in the freshwater ecosystem
Brexit and the Implications of Food Safety Cultural Compliance in the Food Manufacturing Sector
In theory food safety is a critical measurement, not just for economic and legal reasons but also for the moral integrity of the organisation. However, in reality, the number of accidents or incidents particularly in the food manufacturing sector is a serious cause for concern. The problem is further compounded with the onset of Brexit. Given the UK government’s floundering negotiation talks and the pending conservative leadership challenge, it has resulted in a climate of uncertainty, a devaluation of currency and economic instability. Food manufacturers along with other commercial businesses are reluctant to further invest until the economic future is more transparent. In consequence, food manufacturers are seeking efficiency savings, whilst aiming not to compromise food safety compliance. Whilst there are areas of best practice, sadly there are an increasing number of examples in which failure to comply to food safety is resulting in lost of business, serious injury and in certain cases fatalities. This paper addresses Food Safety Cultural Compliance within UK Food Manufacturers and identifies core issues that hinder the establishment of a proactive food safety culture. The research study adopts a mixed methods approach in which five UK food manufacturers were consulted via 15 semi-structured interviews with management and three focused groups. The data collected clearly indicates a commitment to food safety compliance. However, the majority of organisations struggled to maintain consistent levels of food safety compliance despite implementing costly training and development initiatives. Their strategic and operational drive to both enhance and maintain a positive food safety culture was also undermined with the uncertainty of economic pressures and the quagmire of Brexit. The paper concludes with a series of commercially viable recommendations within the context of the Brexit divorce and provides a clear contribution to the community of practice
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