Brain signal processing and neurological therapy

Ph.DDOCTOR OF PHILOSOPH

BIOMECHANICAL CHARACTERISTICS OF THE WRIST JOINT MUSCLE IN CHINESE ADULTS

The purpose of this study was to (1) establish the biomechanical characteristics of the wrist muscle in normal Chinese adults, (2) provide scientific information for the evaluation of sports techniques, strength training, sports injuries, and rehabilitation, (3) provide basic data for muscle building, injury and rehabilitation in the general population. A total of 69 adults cross-country participated in this study. The following conclusions were drawn: (1) With increasing angular velocity, peak torque and total work declined, but average power increased, (2) Peak torque, total work and average power of wrist flexion were greater than wrist extension

Precise Measurements of Branching Fractions for Ds+D_s^+ Meson Decays to Two Pseudoscalar Mesons

We measure the branching fractions for seven $D_{s}^{+}$ two-body decays to pseudo-scalar mesons, by analyzing data collected at $\sqrt{s}=4.178\sim4.226$ GeV with the BESIII detector at the BEPCII collider. The branching fractions are determined to be $\mathcal{B}(D_s^+\to K^+\eta^{\prime})=(2.68\pm0.17\pm0.17\pm0.08)\times10^{-3}$, $\mathcal{B}(D_s^+\to\eta^{\prime}\pi^+)=(37.8\pm0.4\pm2.1\pm1.2)\times10^{-3}$, $\mathcal{B}(D_s^+\to K^+\eta)=(1.62\pm0.10\pm0.03\pm0.05)\times10^{-3}$, $\mathcal{B}(D_s^+\to\eta\pi^+)=(17.41\pm0.18\pm0.27\pm0.54)\times10^{-3}$, $\mathcal{B}(D_s^+\to K^+K_S^0)=(15.02\pm0.10\pm0.27\pm0.47)\times10^{-3}$, $\mathcal{B}(D_s^+\to K_S^0\pi^+)=(1.109\pm0.034\pm0.023\pm0.035)\times10^{-3}$, $\mathcal{B}(D_s^+\to K^+\pi^0)=(0.748\pm0.049\pm0.018\pm0.023)\times10^{-3}$, where the first uncertainties are statistical, the second are systematic, and the third are from external input branching fraction of the normalization mode $D_s^+\to K^+K^-\pi^+$. Precision of our measurements is significantly improved compared with that of the current world average values

Development of Giant Magnetoresistive Device with Perpendicular Magnetic Anisotropy

Ph.DDOCTOR OF PHILOSOPH

Overview of Strategies to Improve Therapy against Tumors Using Natural Killer Cell

NK cells are lymphocytes with antitumor properties and can directly lyse tumor cells in a non-MHC-restricted manner. However, the tumor microenvironment affects the immune function of NK cells, which leads to immune evasion. This may be related to the pathogenesis of some diseases. Therefore, great efforts have been made to improve the immunotherapy effect of natural killer cells. NK cells from different sources can meet different clinical needs, in order to minimize the inhibition of NK cells and maximize the response potential of NK cells, for example, modification of NK cells can increase the number of NK cells in tumor target area, change the direction of NK cells, and improve their targeting ability to malignant cells. Checkpoint blocking is also a promising strategy for NK cells to kill tumor cells. Combination therapy is another strategy for improving antitumor ability, especially in combination with oncolytic viruses and nanomaterials. In this paper, the mechanisms affecting the activity of NK cells were reviewed, and the therapeutic potential of different basic NK cell strategies in tumor therapy was focused on. The main strategies for improving the immune function of NK cells were described, and some new strategies were proposed

Acoustic emission localization based on FBG sensing network and SVR algorithm

Abstract In practical application, carbon fiber reinforced plastics (CFRP) structures are easy to appear all sorts of invisible damages. So the damages should be timely located and detected for the safety of CFPR structures. In this paper, an acoustic emission (AE) localization system based on fiber Bragg grating (FBG) sensing network and support vector regression (SVR) is proposed for damage localization. AE signals, which are caused by damage, are acquired by high speed FBG interrogation. According to the Shannon wavelet transform, time differences between AE signals are extracted for localization algorithm based on SVR. According to the SVR model, the coordinate of AE source can be accurately predicted without wave velocity. The FBG system and localization algorithm are verified on a 500 mm×500 mm×2 mm CFRP plate. The experimental results show that the average error of localization system is 2.8 mm and the training time is 0.07 s

Development of one control and one tumor-specific induced pluripotent stem cell line from laryngeal carcinoma patient

Skin fibroblasts and tumor fibroblasts were extracted from a 64-year old male patient clinically diagnosed with laryngeal carcinoma. Control and tumor specific induced pluripotent stem cells were reprogrammed with 5 reprogramming factors, Klf-4, c-Myc, Oct-4, Sox-2, and Lin-28, using the messenger RNA reprogramming system. The transgene-free iPSC lines showed pluripotency, confirmed by immunofluorescence staining. The iPSC lines also showed normal karyotype, and could form embryoid bodies in vitro and differentiate into the 3 germ layers in vivo. This in vitro cellular model can be used to study the oncogenesis and pathogenesis of laryngeal carcinoma

Impact Properties Analysis of Bamboo/glass Fiber Hybrid Composites

Six kinds of bamboo/glass fiber vinyl ester hybrid composites with different layers were prepared by vacuum assisted resin infusion (VARI) process. The bending and pendulum properties on them, meanwhile the low-velocity impact and compression-after-impacted response were investigated studied on the energy levels of 7J, 9J, 11J and 13J. The results show that the bending strength, pendulum impact strength and peak impact force of the composite materails with two layers of glass fiber beneath the surface are 120%, 220.68% and 371.38% higher than those of the pure bamboo fiber composite, respectively