Demographic and clinical characteristics of the three groups.

<p>Demographic and clinical characteristics of the three groups.</p

Flow velocities of ICAs among three groups.

<p>*Significant difference is found between Group 1 and control group (p<0.001). **Significant difference is found between Group 2 and control group (p<0.001).</p

Prevalence of plaque in ICAs in the three groups.

<p>Group 1 = patients with radiation-induced temporal lobe necrosis; Group 2 = Patients without radiation-induced temporal lobe necrosis; Abbreviation: RICA =  right internal carotid artery; LICA = left internal carotid artery.</p

A: Scan from a 40-year-old healthy individual.

<p>The diameter of the vessel is 7.5 mm, and the IMT is 0.64 mm. B: Scan from a 38-year old nasopharyngeal carcinoma patient with temporal lobe necrosis after radiotherapy shows narrowed vessel lumen (d = 2.2 mm, IMT = 7 mm) and the atherosclerotic plaque. It shows a more than 76% reduction in luminal diameter. Plaque is displayed with arrowhead.</p

Flow velocities of MCAs and BA among three groups.

<p>*The flow velocities of MCAs in Group 1 are much faster than those in control group (p<0.001). ** The flow velocities of MCAs in Group 2 are much faster than those in control group (p<0.001). Also, there is significant difference in MCAs flow velocities between Group 1 and Group 2 (p<0.001).</p

The C-C model-derived survival curves for the nasopharyngeal carcinoma patients in the testing set.

<p>The follow-up prognoses of the nasopharyngeal carcinoma patients in the testing set were clearly identified by the four risk subgroups of the C-C model. (A) The overall survival curves for the L, IL, IH, and H risk subgroups of the C-C model; (B) The distant metastasis-free survival curves for the L, IL, IH, and H risk subgroups of the C-C model; (C) The progression-free survival curves for the L, IL, IH, and H risk subgroups of the C-C model; and (D) The local-regional recurrence-free survival curves for the L, IL, IH, and H risk subgroups of the C-C model. L, low risk, n = 8; IL, intermediate-low risk, n = 38; IH, intermediate-high risk, n = 68; H, high risk, n = 31.</p

The C-C model-derived survival curves for the nasopharyngeal carcinoma patients in the training set.

<p>The follow-up prognoses of the nasopharyngeal carcinoma patients in the training set were clearly identified by the four risk subgroups of the C-C model. (A) The overall survival curves for the L, IL, IH, and H risk subgroups of the C-C model; (B) The distant metastasis-free survival curves for the L, IL, IH, and H risk subgroups of the C-C model; (C) The progression-free survival curves for the L, IL, IH, and H risk subgroups of the C-C model; and (D) The local-regional recurrence-free survival curves for the L, IL, IH, and H risk subgroups of the C-C model. L, low-risk, n = 16; IL, intermediate-low-risk, n = 39; IH, intermediate-high-risk, n = 62; H, high-risk, n = 28.</p

The survival curves for the nasopharyngeal carcinoma patients with high/low serum CXCL5-levels in the training set.

<p>A high sCXCL5 level correlated with poor overall survival and distant metastasis-free survival rates in the training set patients. (A) The overall survival rate was significantly higher in the low sCXCL5 level patients; (B) The distant metastasis-free survival rate was significantly higher in the low sCXCL5 level patients. Low sCXCL5 level, n = 70; high sCXCL5 level, n = 75.</p