ROLE OF SECRETIVE IMMUNOGLOBULINS FOR ALLERGODIAGNOSIS OF RESPIRATORY ALLERGOSA IN CHILDISH AGE

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Electron spin resonance study of anisotropic interactions in a two-dimensional spin gap magnet PHCC

Fine details of the excitation spectrum of the two-dimensional spin-gap magnet PHCC are revealed by electron spin resonance investigations. The values of anisotropy parameters and the orientations of the anisotropy axes are determined by accurate measurements of the angular, frequency-field and temperature dependences of the resonance absorption. The properties of a spin-gap magnet in the vicinity of critical field are discussed in terms of sublevel splittings and g-factor anisotropy.Comment: submitted to PR

OUR EXPERIENCE IN TREATMENT OF CHILDISH ALLERGIC RHINOSINUITIS WITH HYDROCORTIS0N-PHON0PH0RESIS

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KALLIKREIN-KININ SYSTEM (KKS) AND ANGIOTENSIN CONVERTING ENZYME ACTIVITY (ACE) IN PATIENTS ON PERIODIC HA•MODIALYSIS (PHD) TREATED WITH RECOMBINANT HUMAN ERYTHROPOIETIN (rhEPO)

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Conventional Polychemotherapy of Acute Lymphoblastic Leukemia Patients Associated with Oxidative Stress and Antioxidants Depletion

The aim of this study was to investigate whether conventional polychemotherapy of acute lymphoblastic leukemia patients contributed to the development of oxidative stress and antioxidants depletion. Plasma levels of thiobarbituric acid-reactive substances assessed by malonedialdehyde (MDA) content were measured as products of lipid peroxidation. Pretreatment MDA values and MDA values during therapy course were estimated to be above the normal range, indicating the occurrence of oxidative stress. Serum iron levels were monitored as a potential source of non-transferrin bound iron with a role in initiation of oxidative burst. Increased serum iron levels were measured during the whole course of chemotherapy. To analyze the effects of cytostatic therapy on the pro-oxidant/antioxidant parameters in plasma we measured the total antioxidant status (TAS) and a single plasma antioxidant - uric acid (UA). A significant reduction of TAS levels was found at the end of the therapy course, strongly correlating with UA content (r=0,9; p<0,05). Our data suggest that uric acid as a routine laboratory indicator could also serve as a marker of blood antioxidant capacity

STUDY OF SOME INDICES OF KALLIKREIN-KININ SYSTEM AND OF ANGIOTENSIN-CONVERTING ENZYME (KININASE II) IN PLASMA OF RATS ON HEMOPERFUSION WITH NON-ION-EXCHANGE RESIN

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Detection of Fetal Defects in First Trimester by Ultrasound Examination - Abilities and Limitations

The development of prenatal diagnostics in the recent years and the introduction of the new cell free DNA testing for chromosomal abnormalities raised the question about the effectiveness of the well-known First trimester screening. The need to reassess and to determine the efficacy of the 11-14 week scans in detecting fetuses with chromosomal abnormalities and structural defects arose again. Could the First trimester screening be abandoned and replaced by the new tests? In our practice we find that at 11-14 weeks some abnormalities are always detectable, some can never be and others are potentially detectable depending on their association with increased Nuchal translucency (NT). Fetal structural abnormalities can be classified as major or minor and of early or late onset. After the introduction of a national screening program the prenatal detection rates for all congenital anomalies has increased considerably. Especially anencephaly, gastroschisis and exomphalos are amenable for early detection (in the first trimester). The aim of this study was to determine the efficacy of 11-14 week scan in detecting fetuses with structural anomalies that are almost always detectable in the recent years

Mitochondrial DNA Suggests a Western Eurasian origin for Ancient (Proto-) Bulgarians

Ancient (proto-) Bulgarians have long been thought to as a Turkic population. However, evidence found in the past three decades show that this is not the case. Until now, this evidence does not include ancient mitochondrial DNA (mtDNA) analysis. In order to fill this void, we have collected human remains from the VIII-X century AD located in three necropolises in Bulgaria: Nojarevo (Silistra region) and Monastery of Mostich (Shumen region), both in Northeast Bulgaria and Tuhovishte (Satovcha region) in Southwest Bulgaria. The phylogenetic analysis of 13 ancient DNA samples (extracted from teeth) identified 12 independent haplotypes, which we further classified into mtDNA haplogroups found in present-day European and Western Eurasian populations. Our results suggest a Western Eurasian matrilineal origin for proto-Bulgarians as well as a genetic similarity between proto- and modern Bulgarians. Our future work will provide additional data which will further clarify proto-Bulgarian origins; thereby adding new clues to current understanding of European genetic evolution

EFFECTIVENESS OF DIABETIC KETOACIDOSIS TREATMENT WITH LOW-DOSIS VENOUS INSULIN INFUSIONS

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