Hematuria after Orthopedic Tuina: A Case Report and Brief Review of Literature

We present a case of a 24-year-old man who presented hematuria after the orthopedic tuina, which has not been recorded previously in the literature. We review complications of tuina in the literature too

Nonlinear aeroelastic behavior of an airfoil with free-play in transonic flow

An investigation has been made into the nonlinear aeroelastic behavior of an airfoil system with free-play nonlinear stiffness in transonic flow. Computational Fluid Dynamics (CFD) and Reduced Order Model (ROM) based on Euler and Navier-Stokes equations are implemented to calculate unsteady aerodynamic forces. Results show that the nonlinear aeroelastic system experiences various bifurcations with increasing Mach number. Regular subcritical bifurcations are observed in low Mach number region. Subsequently, complex Limit Cycle Oscillations (LCOs) and even non-periodic motions appear at specific airspeed regions. When the Mach number is increased above the freeze Mach number, regular subcritical bifurcations occur again. Comparisons with inviscid solutions are used to identify and elaborate the effect of viscosity with the help of aeroelastic analysis techniques, including root locus, Single Degree of Freedom (SDOF) flutter and aerodynamic influence coefficient (AIC). For low Mach numbers in the transonic regime, the viscosity has little effect on the linear flutter characteristic because of limited influence on AIC, but a remarkable impact on the nonlinear dynamic behavior due to the sensitivity of the nonlinear structure. As the Mach number increases, the viscosity becomes significantly important due to the existence of shock-boundary layer interaction. It affects the unstable mechanism of linear flutter, impacts the aerodynamic center and hence the snap-through phenomenon, influences the AIC and consequently the nonlinear aeroelastic response. When the Mach number is increased further, the shock wave dominates the air flow and the viscosity is of minor importance

Selective Leaching of Zinc from Spent Zinc-Carbon Battery with Ammoniacal Ammonium Carbonate

This paper describes the ammoniacal ammonium carbonate leaching behavior of zinc and manganese from spent zinc-carbon batteries. For selective extraction of Zn from the spent zinc-carbon battery, leaching tests were carried out as a function of process parameters such as concentration of (NH 4 ) 2 CO 3 , ammonia, temperature, time and pulp density. Physical methods of separation such as crushing was applied to reduce the material to 10-20 mm size followed by magnetic separation to separate iron with a recovery about 10 mass% leaving most of Zn and Mn in the non-magnetic fraction. Non-magnetic fraction was further subjected to sieving to separate 2.46 mm over and under size fractions. The oversize material was processed by eddy current separation to recover zinc sheet and carbon rods and plastics. The under size material with chemical composition of Zn 15.5 mass%, Mn 17.5 mass%, and Fe 1.4 mass% was used for leaching studies. Under the optimum leaching conditions (2.0 kmol/m 3 (NH 4 ) 2 CO 3 and 4.0 kmol/m 3 ammonia, 40 C, 100 g/L pulp density, 30 min and 250 rpm), the leaching efficiency of zinc and manganese was 80.2% and less than 0.1%, respectively, indicating the selective recovery of zinc from the spent zinc-carbon battery. An overall zinc recovery is about 88%

Electromagnetic Wave Theory and Remote Sensing

Contains reports on eight research projects.Joint Services Electronics Program (Contract DAAG29-83-K-0003)National Science Foundation (Grant ECS82-03390)Schlumberger-Doll Research CenterNational Aeronautics and Space Administration (Contract NAG5-141)National Aeronautics and Space Administration (Contract NAS5-26861)National Aeronautics and Space Administration (Contract NAG5-270)U.S. Navy - Office of Naval Research (Contract N00014-83-K-0258)International Business Machines, Inc

Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells

Lymphangioleiomyomatosis (LAM) is a progressive neoplastic disorder that leads to lung destruction and respiratory failure primarily in women. LAM is typically caused by tuberous sclerosis complex 2 (TSC2) mutations resulting in mTORC1 activation in proliferative smooth muscle–like cells in the lung. The female predominance of LAM suggests that estradiol contributes to disease development. Metabolomic profiling identified an estradiol-enhanced prostaglandin biosynthesis signature in Tsc2-deficient (TSC−) cells, both in vitro and in vivo. Estradiol increased the expression of cyclooxygenase-2 (COX-2), a rate-limiting enzyme in prostaglandin biosynthesis, which was also increased at baseline in TSC-deficient cells and was not affected by rapamycin treatment. However, both Torin 1 treatment and Rictor knockdown led to reduced COX-2 expression and phospho-Akt-S473. Prostaglandin production was also increased in TSC-deficient cells. In preclinical models, both Celecoxib and aspirin reduced tumor development. LAM patients had significantly higher serum prostaglandin levels than healthy women. 15-epi-lipoxin-A4 was identified in exhaled breath condensate from LAM subjects and was increased by aspirin treatment, indicative of functional COX-2 expression in the LAM airway. In vitro, 15-epi-lipoxin-A4 reduced the proliferation of LAM patient–derived cells in a dose-dependent manner. Targeting COX-2 and prostaglandin pathways may have therapeutic value in LAM and TSC-related diseases, and possibly in other conditions associated with mTOR hyperactivation