33 research outputs found

    The Other Press, January 5, 1990

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    <p>The crude earthworm extract catalysed domino reactions for the synthesis of coumarin derivatives.</p

    Expression analysis on 14-3-3 proteins in regenerative liver following partial hepatectomy

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    <div><p>Abstract 14-3-3 proteins play a vital part in the regulation of cell cycle and apoptosis as signaling integration points. During liver regeneration, the quiescent hepatocytes go through hypertrophy and proliferation to restore liver weight. Therefore, we speculated that 14-3-3 proteins regulate the progression of liver regeneration. In this study, we analyzed the expression patterns of 14-3-3 proteins during liver regeneration of rat to provide an insight into the regenerative mechanism using western blotting. Only four isoforms (γ, ε, σ and τ/θ) of the 14-3-3 proteins were expressed in regenerative liver after partial hepatectomy (PH). The dual effects, the significant down-regulation of 14-3-3ε and the significant up-regulation of 14-3-3τ/θ at 2 h after PH, might play particularly important roles in S-phase entry. The significant peaks of 14-3-3σ at 30 h and of ε and τ/θ at 24 h might be closely related not only to the G2/M transition but also to the size of hepatocytes. Possibly, the peak of 14-3-3ε expression seen at 168 h plays critical roles in the termination of liver regeneration by inhibiting cellular proliferation.</p></div

    Multiplexed Imaging of Trace Residues in a Single Latent Fingerprint

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    The development of highly sensitive, selective, nondestructive, and multiplexed imaging modalities is essential for latent fingerprint (LFP) identification and fingerprint residues detection. Herein, we present a versatile strategy to identify LFPs and to probe the multiple trace residues in a single LFP simultaneously. With the purpose of achieving high sensitivity, we for the first time introduced a polydopamine (PDA)-triggered Au growth method to prepare superbright and multiplex surface-enhanced Raman scattering (SERS) tags, which were endowed with high selectivity by conjugating with specific antibodies. In combination with a rapid Raman mapping technique, the sensitivity of the SERS probes was down to picogram scale and all the three levels of LFP features can be clearly seen. More significantly, the multiplexed imaging of diverse residues in a single LFP provides more accurate information than that using monochromatic imaging of individuals alone. The high analytical figures of merit enable this approach great promise for use in the fields ranging from chemical detection to molecular imaging

    Parameter estimates of the selected models for different components by age groups using SUR method.

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    <p>Parameter estimates of the selected models for different components by age groups using SUR method.</p

    The relationship between the predicted biomass and observed biomass for four components in middle-aged forest.

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    <p>The relationship between the predicted biomass and observed biomass for four components in middle-aged forest.</p

    Tree Biomass Allocation and Its Model Additivity for <i>Casuarina equisetifolia</i> in a Tropical Forest of Hainan Island, China

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    <div><p><i>Casuarina equisetifolia</i> is commonly planted and used in the construction of coastal shelterbelt protection in Hainan Island. Thus, it is critical to accurately estimate the tree biomass of <i>Casuarina equisetifolia</i> L. for forest managers to evaluate the biomass stock in Hainan. The data for this work consisted of 72 trees, which were divided into three age groups: young forest, middle-aged forest, and mature forest. The proportion of biomass from the trunk significantly increased with age (<i>P</i><0.05). However, the biomass of the branch and leaf decreased, and the biomass of the root did not change. To test whether the crown radius (<i>CR</i>) can improve biomass estimates of <i>C</i>. <i>equisetifolia</i>, we introduced <i>CR</i> into the biomass models. Here, six models were used to estimate the biomass of each component, including the trunk, the branch, the leaf, and the root. In each group, we selected one model among these six models for each component. The results showed that including the <i>CR</i> greatly improved the model performance and reduced the error, especially for the young and mature forests. In addition, to ensure biomass additivity, the selected equation for each component was fitted as a system of equations using seemingly unrelated regression (SUR). The SUR method not only gave efficient and accurate estimates but also achieved the logical additivity. The results in this study provide a robust estimation of tree biomass components and total biomass over three groups of <i>C</i>. <i>equisetifolia</i>.</p></div

    Parameter estimates and model evaluation statistics of each biomass model for the young forest.

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    <p>Parameter estimates and model evaluation statistics of each biomass model for the young forest.</p

    The relationship between the predicted biomass and observed biomass for four components in young forest.

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    <p>The relationship between the predicted biomass and observed biomass for four components in young forest.</p
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