4,248 research outputs found
Protein Fractions from Korean Mistletoe ( Viscum Album coloratum
Mistletoe (Viscum Album coloratum) has been known as a medicinal plant in European and Asian countries. Recent data show that biological activity of mistletoe alleviates hypertension, heart disease, renal failure, and cancer development. In this study, we report the antidiabetic effect of Korean mistletoe extract (KME). KME treatments enhanced the insulin secretion from the pancreatic β-cell without any effects of cytotoxicity. PDX-1 and beta2/neuroD known as transcription factors that regulate the expression of insulin gene were upregulated by treatment of the KME protein fractions isolated by ion-exchange chromatography after ammonium sulfate precipitation. Furthermore, these KME protein fractions significantly lowered the blood glucose level and the volume of drinking water in alloxan induced hyperglycemic mice. Taken together with the findings, it provides new insight that KME might be served as a useful source for the development of medicinal reagent to reduce blood glucose level of type I diabetic patients
Quasi-Eigenstate Evolution in Open Chaotic Billiards
We experimentally studied evolution of quasi-eigenmodes as classical dynamics
undergoing a transition from being regular to chaotic in open quantum
billiards. In a deformation-variable microcavity we traced all high-Q cavity
modes in a wide range of frequency as the cavity deformation increased. By
employing an internal parameter we were able to obtain a mode-dynamics diagram
at a given deformation, showing avoided crossings between different mode
groups, and could directly observe the coupling strengths induced by ray chaos
among encountering modes. We also show that the observed mode-dynamics diagrams
reflect the underlying classical ray dynamics in the phase space.Comment: 4 pages, 4 figure
Development of deformation-tunable quadrupolar microcavity
We have developed a technique for realizing a two-dimensional quadrupolar
microcavity with its deformation variable from 0% to 20% continuously. We
employed a microjet ejected from a noncircular orifice in order to generate a
stationary column with modulated quadrupolar deformation in its cross section.
Wavelength red shifts of low-order cavity modes due to shape deformation were
measured and were found to be in good agreement with the wave calculation for
the same deformation, indicating the observed deformation is quadrupolar in
nature.Comment: 7 pages, 6 figures, intended for Rev. Sci. Instu
Chaos-assisted nonresonant optical pumping of quadrupole-deformed microlasers
Efficient nonresonant optical pumping of a high-Q scar mode in a
two-dimensional quadrupole-deformed microlaser has been demonstrated based on
ray and wave chaos. Three-fold enhancement in the lasing power was achieved at
a properly chosen pumping angle. The experimental result is consistent with ray
tracing and wave overlap integral calculations.Comment: 3 pages, 5 figure
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