116,965 research outputs found

    Learning a Mixture of Deep Networks for Single Image Super-Resolution

    Full text link
    Single image super-resolution (SR) is an ill-posed problem which aims to recover high-resolution (HR) images from their low-resolution (LR) observations. The crux of this problem lies in learning the complex mapping between low-resolution patches and the corresponding high-resolution patches. Prior arts have used either a mixture of simple regression models or a single non-linear neural network for this propose. This paper proposes the method of learning a mixture of SR inference modules in a unified framework to tackle this problem. Specifically, a number of SR inference modules specialized in different image local patterns are first independently applied on the LR image to obtain various HR estimates, and the resultant HR estimates are adaptively aggregated to form the final HR image. By selecting neural networks as the SR inference module, the whole procedure can be incorporated into a unified network and be optimized jointly. Extensive experiments are conducted to investigate the relation between restoration performance and different network architectures. Compared with other current image SR approaches, our proposed method achieves state-of-the-arts restoration results on a wide range of images consistently while allowing more flexible design choices. The source codes are available in http://www.ifp.illinois.edu/~dingliu2/accv2016

    Spin filtering implemented through Rashba and weak magnetic modulations

    Full text link
    We present two theoretical schemes for spin filters in one-dimensional semiconductor quantum wires with spatially modulated Rashba spin-orbit coupling (SOC) as well as weak magnetic potential. For case I, the SOC is periodic and the weak magnetic potential is applied uniformly along the wire. Full spin polarizations with opposite signs are obtained within two separated energy intervals. For case II, the weak magnetic potential is periodic while the SOC is uniform. An ideal negative/positive switching effect for spin polarization is realized by tuning the strength of SOC. The roles of SOC, magnetic potential, and their coupling on the spin filtering are analyzed.Comment: 4 pages, 4 figure

    Methylation of CpG island is not a ubiquitous mechanism for the loss of oestrogen receptor in breast cancer cells.

    Get PDF
    Methylation has been shown to play an important role in the down-regulation of oestrogen receptors (ER) in breast cancer cells. One critical question that remains unclear is whether methylation can account for the loss of ER expression in cells derived from an ER-positive cell line. This laboratory has established an in vitro cell system using long-term growth of human ER-positive breast cancer cell line T47D in oestrogen-free medium. A clonal cell line, T47D:C4:2 (C4:2), has been characterized. Unlike T47D:A18 (A18), which is a T47D line maintained in oestrogen medium, C4:2 has lost the expression of ER and hormone responsiveness. DNA fingerprinting and restriction fragment length polymorphism (RFLP) analysis results confirmed that C4:2 was of the same lineage as A18. These cell lines provide an invaluable system to study the mechanism of ER expression and regulatory pathways leading to hormone-independent growth. The results here clearly demonstrate that the ER CpG island in C4:2 cells remains unmethylated. The loss of ER in the cell line must be due to mechanisms other than methylation. We also evaluated the ER CpG island in the MDA-MB-231:10A (10A) cell line, which is a clone from the MDA-MB-231 line obtained from ATCC and the DNA from the MDA-MB-231 cell line used in the original report. Unlike the cell line from the report, which showed a full methylation pattern in the island, the 10A line only showed a partial methylation pattern in the CpG island. Possible mechanisms pertaining to the heterogeneous methylation pattern of the ER CpG island in the breast cancer cells are discussed

    Tackling Challenges in Seebeck Coefficient Measurement of Ultra-High Resistance Samples with an AC Technique

    Get PDF
    Seebeck coefficient is a widely studied semiconductor property. Conventional Seebeck coefficient measurements are based on DC voltage measurement. Normally this is performed on samples with moderate resistances (e.g., below a few MΩ level). Certain semiconductors are intrinsic and highly resistive. Many examples can be found in optical and photovoltaic materials. The hybrid halide perovskites that have gained extensive attention recently are a good example. Despite great attention from the materials and physics communities, few successful studies exist of the Seebeck coefficient of these compounds, for example CH3NH3PbI3. An AC-technique-based Seebeck coefficient measurement is reported, which makes high-quality Seebeck voltage measurements on samples with resistances up to the 100 GΩ level. This is achieved through a specifically designed setup to enhance sample isolation and increase capacitive impedance. As a demonstration, Seebeck coefficient measurement of a CH3NH3PbI3 thin film is performed at dark, with sample resistance 150 GΩ, and found S = +550 µV K−1. The strategy reported could be applied to the studies of fundamental transport parameters of all intrinsic semiconductors that have not been feasible
    corecore