87 research outputs found
SSC-RS: Elevate LiDAR Semantic Scene Completion with Representation Separation and BEV Fusion
Semantic scene completion (SSC) jointly predicts the semantics and geometry
of the entire 3D scene, which plays an essential role in 3D scene understanding
for autonomous driving systems. SSC has achieved rapid progress with the help
of semantic context in segmentation. However, how to effectively exploit the
relationships between the semantic context in semantic segmentation and
geometric structure in scene completion remains under exploration. In this
paper, we propose to solve outdoor SSC from the perspective of representation
separation and BEV fusion. Specifically, we present the network, named SSC-RS,
which uses separate branches with deep supervision to explicitly disentangle
the learning procedure of the semantic and geometric representations. And a BEV
fusion network equipped with the proposed Adaptive Representation Fusion (ARF)
module is presented to aggregate the multi-scale features effectively and
efficiently. Due to the low computational burden and powerful representation
ability, our model has good generality while running in real-time. Extensive
experiments on SemanticKITTI demonstrate our SSC-RS achieves state-of-the-art
performance.Comment: 8 pages, 5 figures, IROS202
OFAR: A Multimodal Evidence Retrieval Framework for Illegal Live-streaming Identification
Illegal live-streaming identification, which aims to help live-streaming
platforms immediately recognize the illegal behaviors in the live-streaming,
such as selling precious and endangered animals, plays a crucial role in
purifying the network environment. Traditionally, the live-streaming platform
needs to employ some professionals to manually identify the potential illegal
live-streaming. Specifically, the professional needs to search for related
evidence from a large-scale knowledge database for evaluating whether a given
live-streaming clip contains illegal behavior, which is time-consuming and
laborious. To address this issue, in this work, we propose a multimodal
evidence retrieval system, named OFAR, to facilitate the illegal live-streaming
identification. OFAR consists of three modules: Query Encoder, Document
Encoder, and MaxSim-based Contrastive Late Intersection. Both query encoder and
document encoder are implemented with the advanced OFA encoder, which is
pretrained on a large-scale multimodal dataset. In the last module, we
introduce contrastive learning on the basis of the MaxiSim-based late
intersection, to enhance the model's ability of query-document matching. The
proposed framework achieves significant improvement on our industrial dataset
TaoLive, demonstrating the advances of our scheme
DetZero: Rethinking Offboard 3D Object Detection with Long-term Sequential Point Clouds
Existing offboard 3D detectors always follow a modular pipeline design to
take advantage of unlimited sequential point clouds. We have found that the
full potential of offboard 3D detectors is not explored mainly due to two
reasons: (1) the onboard multi-object tracker cannot generate sufficient
complete object trajectories, and (2) the motion state of objects poses an
inevitable challenge for the object-centric refining stage in leveraging the
long-term temporal context representation. To tackle these problems, we propose
a novel paradigm of offboard 3D object detection, named DetZero. Concretely, an
offline tracker coupled with a multi-frame detector is proposed to focus on the
completeness of generated object tracks. An attention-mechanism refining module
is proposed to strengthen contextual information interaction across long-term
sequential point clouds for object refining with decomposed regression methods.
Extensive experiments on Waymo Open Dataset show our DetZero outperforms all
state-of-the-art onboard and offboard 3D detection methods. Notably, DetZero
ranks 1st place on Waymo 3D object detection leaderboard with 85.15 mAPH (L2)
detection performance. Further experiments validate the application of taking
the place of human labels with such high-quality results. Our empirical study
leads to rethinking conventions and interesting findings that can guide future
research on offboard 3D object detection.Comment: 17 pages, 8 figure
Intrinsic nonlinear Hall effect and gate-switchable Berry curvature sliding in twisted bilayer graphene
Though the observation of quantum anomalous Hall effect and nonlocal
transport response reveals nontrivial band topology governed by the Berry
curvature in twisted bilayer graphene, some recent works reported nonlinear
Hall signals in graphene superlattices which are caused by the extrinsic
disorder scattering rather than the intrinsic Berry curvature dipole moment. In
this work, we report a Berry curvature dipole induced intrinsic nonlinear Hall
effect in high-quality twisted bilayer graphene devices. We also find that the
application of the displacement field substantially changes the direction and
amplitude of the nonlinear Hall voltages, as a result of a field-induced
sliding of the Berry curvature hotspots. Our work not only proves that the
Berry curvature dipole could play a dominant role in generating the intrinsic
nonlinear Hall signal in graphene superlattices with low disorder densities,
but also demonstrates twisted bilayer graphene to be a sensitive and
fine-tunable platform for second harmonic generation and rectification
Reliability of foot posture index (FPI-6) for evaluating foot posture in patients with knee osteoarthritis
Objective: To determine the reliability of FPI-6 in the assessment of foot posture in patients with knee osteoarthritis (KOA).Methods: Thirty volunteers with KOA (23 females, 7 males) were included in this study, assessed by two raters and at three different moments. Inter-rater and test-retest reliability were assessed with Cohen’s Weighted Kappa (Kw) and Intraclass Correlation Coefficient (ICC). Bland-Altman plots and respective 95% limits of agreement (LOA) were used to assess both inter-rater and test-retest agreement and identify systematic bias. Moreover, the internal consistency of FPI-6 was assessed by Spearman’s correlation coefficient.Results: FPI-6 total score showed a substantial inter-rater (Kw = .66) and test-retest reliability (Kw = .72). The six items of FPI-6 demonstrated inter-rater and test-retest reliability varying from fair to substantial (Kw = .33 to .76 and Kw = .40 to .78, respectively). Bland-Altman plots and respective 95% LOA indicated that there appeared no systematic bias and the acceptable agreement of FPI-6 total score for inter-rater and test-retest was excellent. There was a statistically significant positive correlation between each item and the total score of FPI-6, which indicated that FPI-6 had good internal consistency.Conclusion: In conclusion, the reliability of FPI-6 total score and the six items of FPI-6 were fair to substantial. The results can provide a reliable way for clinicians and researchers to implement the assessment of foot posture in patients with KOA
TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein
Background
The tripartite motif (TRIM) family of proteins plays a key role in the developmental growth and therapeutic resistance of many tumors. However, the regulatory mechanisms and biological functions of TRIM proteins in human glioblastoma (GBM) are not yet fully understood. In this study, we focused on TRIM56, which emerged as the most differentially expressed TRIM family member with increased expression in GBM.
Methods
Western blot, real-time quantitative PCR (qRT-PCR), immunofluorescence (IF) and immunohistochemistry (IHC) were used to study the expression levels of TRIM56 and cIAP1 in GBM cell lines. Co-immunoprecipitation (co-IP) was used to explore the specific binding between target proteins and TRIM56. A xenograft animal model was used to verify the tumor promoting effect of TRIM56 on glioma in vivo.
Results
We observed elevated expression of TRIM56 in malignant gliomas and revealed that TRIM56 promoted glioma progression in vitro and in a GBM xenograft model in nude mice. Analysis of the Human Ubiquitin Array and co-IPs showed that cIAP1 is a protein downstream of TRIM56. TRIM56 deubiquitinated cIAP1, mainly through the zinc finger domain (amino acids 21–205) of TRIM56, thereby reducing the degradation of cIAP1 and thus increasing its expression. TRIM56 also showed prognostic significance in overall survival of glioma patients.
Conclusions
TRIM56-regulated post-translational modifications may contribute to glioma development through stabilization of cIAP1. Furthermore, TRIM56 may serve as a novel prognostic indicator and therapeutic molecular target for GBM.publishedVersio
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