Multi-dimensional vibration sensing and simultaneous self-homodyne optical transmission of single wavelength net 5.36 Tb/s signal using telecom 7-core fiber

We present a high-capacity self-homodyne optical transmission system that enables simultaneously multidimensional vibration sensing based on a weakly-coupled 7-core fiber. To our knowledge, we demonstrate for the first-time detection of fiber vibration direction along with strength, frequency, and location of the vibration source, while transmitting in the meantime single-carrier 16 QAM signal reaching a net date rate of 5.36 Tb/s over 41.4 km of telecom 7-core fiber.Comment: 5 pages, 4 figure

Reconfiguration of Gut Microbiota and Reprogramming of Liver Metabolism with Phycobiliproteins Bioactive Peptides to Rehabilitate Obese Rats

Phycobiliproteins (derived from Arthrospira platensis) bioactive peptide extracts (PPE) possess multiple pharmacological effects in the mitigation of human metabolic disorders. The role of PPE in the treatment of diet-induced obesity and the understanding of the underlying mechanism between the gut microbiome and metabolic blood circulation for obese patients remains poorly understood. In this study, we showed that PPE attenuated obesity by reducing body weight, and ameliorated glucose and lipid indexes in serum. In particular, PPE is postulated to mitigate liver steatosis and insulin resistance. On the other hand, dietary treatment with PPE was found to “reconfigure” the gut microbiota in the way that the abundances were elevated for Akkermansia_muciniphila, beneficial Lactobacillus and Romboutsia, SCFA-producing species Faecalibacterium prausnitzii, Lachnospiraceae_bacterium, Clostridiales_bacterium, probiotics Clostridium sp., Enterococcus faecium, and Lactobacillus_johnsonii, while the abundance of Firmicutes was reduced and that of Bacteroidetes was increased to reverse the imbalance of Firmicutes/Bacteroidetes ratio. Finally, the metabolomics of circulating serum using UHPLC-MS/MS illustrated that PPE supplementation indeed promoted lipid metabolism in obese rats. As summary, it was seen that PPE reprogrammed the cell metabolism to prevent the aggravation of obesity. Our findings strongly support that PPE can be regarded as a potential therapeutic dietary supplement for obesity

Effects of W/Co co-doping on the structural, multiferroic, dielectric and optical properties of filled tungsten bronze Ba4Sm2Fe2Nb8O30 ceramics

The structural, magnetic, ferroelectric, dielectric, magneto-dielectric and optical properties of W/Co co-substituted tungsten bronze Ba4Sm2Fe2Nb8-3x(W2Co)xO30 (0 ≤ x ≤ 0.3) ceramics were studied in detail. All the samples can be indexed with the tetragonal structure with the space group of P4bm. The room-temperature ferromagnetism with rather high ferromagnetic Curie temperature Tc was obtained in all compositions. The co-doping of W/Co ions obviously optimized the ferromagnetism and ferroelectricity. The composition x  = 0.2 showed a superior multiferroicity with the remnant magnetization Mr of 0.15 emu/g and the remnant polarization Pr of 2.1μC/cm2 as well as the Tc of 886 K. The low-temperature relaxation was related to the thermal process of oxygen vacancies, while the another one around 300 K was ascribed to the localized hopping of electrons. The relative increment of magneto-dielectric constant (MDC) obeyed with the square term of magnetization in Ginzburg-Landau theory, implying the existence of intrinsic magneto-electric coupling effect. A relatively large MDC of 0.17 % was achieved in pure sample. In addition, two direct inter-band transitions with the narrow band gaps of ∼2.0 eV and ∼2.5 eV were demonstrated

Table_2_Identification and virtual screening of novel salty peptides from hydrolysate of tilapia by-product by batch molecular docking.docx

IntroductionTilapia produces a large number of by-products during processing, which contain potentially flavorful peptides.MethodsThe application of PyRx software enabled batch molecular docking andscreening of 16 potential salty peptides from 189 peptides identified in the enzymaticdigestion of tilapia by-products.ResultsAccording to sensory analysis, all 16 peptides werepredominantly salty with a threshold of 0.256 - 0.379 mmol/L with some sournessand astringency, among which HLDDALR had the highest salty intensity, followedby VIEPLDIGDDKVR, FPGIPDHL, and DFKSPDDPSRH. I addition, moleculardocking results showed these four core peptides with high salt intensity bound to thesalt receptor TRPV1 mainly via van der Waals interactions, hydrogen bonds, andhydrophobic forces; Arg491, Tyr487, VAL441, and Asp708 were the key sites for thebinding of salty peptides to TRPV1. Therefore, the application of batch moleculardocking using PyRx is effective and economical for the virtual screening of saltypeptides.</p

Table_1_Identification and virtual screening of novel salty peptides from hydrolysate of tilapia by-product by batch molecular docking.docx

IntroductionTilapia produces a large number of by-products during processing, which contain potentially flavorful peptides.MethodsThe application of PyRx software enabled batch molecular docking andscreening of 16 potential salty peptides from 189 peptides identified in the enzymaticdigestion of tilapia by-products.ResultsAccording to sensory analysis, all 16 peptides werepredominantly salty with a threshold of 0.256 - 0.379 mmol/L with some sournessand astringency, among which HLDDALR had the highest salty intensity, followedby VIEPLDIGDDKVR, FPGIPDHL, and DFKSPDDPSRH. I addition, moleculardocking results showed these four core peptides with high salt intensity bound to thesalt receptor TRPV1 mainly via van der Waals interactions, hydrogen bonds, andhydrophobic forces; Arg491, Tyr487, VAL441, and Asp708 were the key sites for thebinding of salty peptides to TRPV1. Therefore, the application of batch moleculardocking using PyRx is effective and economical for the virtual screening of saltypeptides.</p

Data_Sheet_1_Identification and virtual screening of novel salty peptides from hydrolysate of tilapia by-product by batch molecular docking.docx

IntroductionTilapia produces a large number of by-products during processing, which contain potentially flavorful peptides.MethodsThe application of PyRx software enabled batch molecular docking andscreening of 16 potential salty peptides from 189 peptides identified in the enzymaticdigestion of tilapia by-products.ResultsAccording to sensory analysis, all 16 peptides werepredominantly salty with a threshold of 0.256 - 0.379 mmol/L with some sournessand astringency, among which HLDDALR had the highest salty intensity, followedby VIEPLDIGDDKVR, FPGIPDHL, and DFKSPDDPSRH. I addition, moleculardocking results showed these four core peptides with high salt intensity bound to thesalt receptor TRPV1 mainly via van der Waals interactions, hydrogen bonds, andhydrophobic forces; Arg491, Tyr487, VAL441, and Asp708 were the key sites for thebinding of salty peptides to TRPV1. Therefore, the application of batch moleculardocking using PyRx is effective and economical for the virtual screening of saltypeptides.</p

Data File 3: Order-of-magnitude multiphoton signal enhancement based on characterization of absorption spectra of immersion oils at the 1700-nm window

supplementary material 3 Originally published in Optics Express on 20 March 2017 (oe-25-6-5909