Epidemiology of Functional Abdominal Bloating and Its Impact on Health Related Quality of Life: Male-Female Stratified Propensity Score Analysis in a Population Based Survey in Mainland China

<div><p>Background</p><p>The epidemiology of Functional abdominal bloating (FAB) and its impact on health-related quality of life (HRQoL) in Chinese people remains unclear.</p><p>Methods</p><p>Randomised, stratified, multi-stage sampling methodology was used to select a representative sample of the general population from five cities in China (n = 16,078). All respondents completed the modified Rome II questionnaire; 20% were asked to complete the 36-item Short Form (SF-36). The associated factors of FAB were analyzed. The effects of FAB on HRQoL were estimated with gender stratification using propensity score techniques in 20% subsample.</p><p>Results</p><p>Overall, 643 individuals (4.00%) had FAB and it was more prevalent in males than in females (4.87% vs. 3.04%, <i>P</i><0.001). For males, self-reported history of dyspepsia was most strongly associated with FAB (OR = 2.78; 95% CI: 1.59, 4.72). However, the most strongly associated factor was self-reported health status for females (moderate health vs. good health: OR = 2.06, 95% CI: 1.07, 3.96. <i>P</i> = 0.030; poor health vs. good health: OR = 5.71, 95% CI: 2.06, 15.09). Concerning HRQoL, FAB was found to be related to two domains: role limitation due to physical problems (<i>P</i> = 0.030) and bodily pain (<i>P</i><0.001) in females. While, in males, there were significant differences in multiple domains between those with and without FAB.</p><p>Conclusion</p><p>The prevalence of FAB in China was lower than previous reports. Males who had ever been diagnosed with dyspepsia and females who were in a poor self-reported health status were correlated with a higher prevalence of FAB. FAB affected only physical health in females, but impaired both physical and mental health in males.</p></div

Relative influence of the top10 potential associated factors for functional abdominal bloating using generalized boosted models, a cross sectional study in five cities, china, 2007–2008 (n = 16,078).

<p>Relative influence of the top10 potential associated factors for functional abdominal bloating using generalized boosted models, a cross sectional study in five cities, china, 2007–2008 (n = 16,078).</p

Palladium-Catalyzed Cyclization Reaction of Oxime Acetates and Aryl Iodides: Syntheses of 2‑Imidazolines

A novel and versatile method for the synthesis of 2-imidazolines has been developed via the Pd-catalyzed cyclization reaction of readily available homoallenyl oxime acetates with aryl iodides. This protocol is performed under mild reaction conditions and needs no additives or ligands

Characteristics of baseline covariates with <i>p</i><0.05 before adjusted and standardized bias before and after PS adjusted using weighting in 20% of the total respondents, a cross sectional study in five cities, china, 2007–2008 (n = 3,179).

<p>*<i>P</i><0.05.</p><p>**<i>P</i><0.001.</p

The prevalence of functional abdominal bloating from a cross sectional study in five cities, china, 2007–2008(n = 16,078).

<p>*<i>P</i><0.05, Chi-squared Test.</p><p>**<i>P</i><0.01.</p>a<p>Cochran–Armitage test.</p

Effect of FAB on health related quality of life by males and females separately, with propensity score techniques to control the confounding factors in 20% of the total respondents, a cross sectional study in five cities, china, 2007–2008 (n = 3,179).

<p>Role emotional refers to role limitations due to emotional problems; Role physical, refers to role limitations due to physical problems;</p><p>*<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001;</p>a<p>The brief self-administered questionnaire SF-36 was used to measure health related quality of life. Item scores for each SF-36 domains were coded, summed and transformed to a scale from 0 (worst possible health state) to 100 (best possible health state).</p

Additional file 2: of Memory retrieval in addiction: a role for miR-105-mediated regulation of D1 receptors in mPFC neurons projecting to the basolateral amygdala

Data values for all experiments where n<6. (DOCX 17 kb