Forty Years after Poverty Reduction in China: The Role of Women’s Empowerment in Enhancing Food Security and Diet Diversity

This study analyzed the role of women’s empowerment in diversifying the diet of households through their own production. Developed from empowerment and food security theories, this study constructed measures from the household dietary diversity score (HDDS) and Women’s Empowerment Index (WEI). The study focused on poverty-stricken regions in China and conducted a thematic questionnaire-based household survey on gender and food consumption in 2021. Based on micro-level evidence from 1199 rural households, this research found a low score of women’s empowerment and an average WEI of 0.689; the status of diet diversity, measured by the HDDS, varied by income and social class; and the average rate was low. Agricultural production diversity and women’s empowerment are positively associated with diet diversity. There is strong evidence that women’s employment mitigates the side effects of decreasing production diversity on households’ diet security. As a result, women’s empowerment can potentially mitigate the adverse consequences of low agricultural diversification in household diet quality in less developed areas. This study provides evidence for repurposing food and agricultural policies toward healthy diets and gender-responsive agrifood systems

Production Choices and Food Security: A Review of Studies Based on a Micro-Diversity Perspective

Given the ‘subsistence’ character of smallholder production, agricultural production diversification is often seen as an effective strategy for smallholders to improve their diets’ diversity and nutritional status, yet the existing evidence remains inadequate. The study applies bibliometric data from the “Web of Science” database to synthesize 46 papers from developing countries to explore the relationship between production diversity, dietary diversity, and nutrition in smallholder households. The study identifies the most influential journals, authors, organizations, and countries and reveals research themes related to agricultural production and food security. This data analysis can help researchers target potential collaborators and access influential literature in agricultural production diversity and dietary diversity research. In addition, the results showed that agricultural production diversity potentially influences households’ dietary diversity, with mixed results: Agricultural production diversification is the primary way to improve food and nutritional security among smallholder families with low socio-economic status, inaccessible transportation, and poverty; market access and trade have more potential to improve dietary diversity among smallholder households with well-developed markets and higher income levels; the significant measures of agricultural production diversity include Crop Counts, FGPD, SI, and SWDI; the significant measures of dietary diversity include HDDS and IDDS. This paper provides a roadmap for agricultural production and food security researchers by conducting a systematic review of the literature, summarizing some research methods and perspectives applicable to local socio-economic development

Click chemistry for 3D bioprinting

Bioinks are employed in the fabrication of 3D scaffolds containing cells and macromolecules that can be applied in regenerative medicine.info:eu-repo/semantics/publishe

Data set from the phosphoproteomic analysis of Magnaporthe oryzae-responsive proteins in susceptible and resistant rice cultivars

Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is the most destructive disease of rice and causes tremendous losses of rice yield worldwide. To explore the molecular mechanisms involved in the rice–M. oryzae interaction, we conducted a time-course phosphoproteomic analysis of leaf samples from resistant and susceptible rice cultivars infected with M. oryzae. This data article contains additional results and analysis of M. oryzae-regulated phosphoproteins in rice leaves [1]. We report the analysis of M. oryzae-regulated phosphoproteins at all time points, including Venn diagram analysis, close-up views, relative intensities, and functional category, and the MS spectra of representative phosphoprotein and representative phosphorylated peptides

Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia

info:eu-repo/semantics/publishe

Core-shell structured microneedles with programmed drug release functions for prolonged hyperuricemia management

An appropriate non-oral platform via transdermal delivery of drugs is highly recommended for the treatment of hyperuricemia. Herein, a core-shell structured microneedle array patch with programmed drug release functions was designed to regulate serum...info:eu-repo/semantics/publishe

Evaluating the screening value of serum light chain ratio, β2 microglobulin, lactic dehydrogenase and immunoglobulin in patients with multiple myeloma using ROC curves.

ObjectiveSeveral laboratory and imaging assays are required to diagnose multiple myeloma (MM). Serum and urine immunofixation electrophoresis are two key assays to diagnose MM, while they have not been extensively utilized in Chinese hospitals. Serum light chain (sLC), β2 microglobulin (β2-MG), lactic dehydrogenase (LDH), and immunoglobulin (Ig) are routinely measured in the majority of Chinese hospitals. Imbalance of sLC ratio (involved light chain/uninvolved light chain) is frequently observed in MM patients. This study aimed to evaluate the screening value of sLC ratio, β2-MG, LDH, and Ig in MM patients using receiver operating characteristic (ROC) curves.MethodsData of 303 suspected MM patients, who were admitted to the Taizhou Central Hospital between March 2015 and July 2021, were retrospectively analyzed. In total, 69 patients (MM arm) met the International Myeloma Working Group (IMWG) updated criteria for the diagnosis of MM, while 234 patients were non-MM (non-MM arm). All patients' sLC, β2-MG, LDH, and Ig were measured using commercially available kits according to the manufacturer's instructions. The ROC curve analysis was employed to assess the screening value of sLC ratio, β2-MG, LDH, creatinine (Cr) and Ig. The statistical analysis was carried out by SPSS 26.0 (IBM, Armonk, NY, USA) and MedCalc 19.0.4 (Ostend, Belgium) software.ResultsThere was no significant difference between the MM and non-MM arms in terms of gender, age and Cr. The median sLC ratio in the MM arm was 11.5333, which was significantly higher than that of 1.9293 in the non-MM arm (PConclusionThe triple combination strategy (sLC ratio, 3.2121; β2-MG, 1.95 mg/L; Ig, 46.4 g/L) is accompanied by remarkable sensitivity and specificity for screening MM in Chinese hospitals

Hollow-adjustable polymer microneedles for prolonged hypoglycemic effect on diabetic rats

Maintaining blood glucose levels within a safe range is critical for diabetic management. In recent decades, microneedles (MNs) have emerged as a potential method for delivering drugs to treat diabetes. However, insufficient drug loading and the complexity of achieving long-acting release have presented challenges that research has not addressed well. In this study, the hollow-adjustable biocompatible polymer MNs with varying cavity volumes were developed by cyclic freeze-thawing technique. The structure of shell-layer of hollow MNs was optimized with a sequential casting approach for regulating drug release kinetics. This design can ensure the sufficient mechanical strength of MNs and help to improve the drug-loading capacity, thereby solving the problem of low drug-loading capacity and short pharmacodynamic action time of traditional polymer MNs. In vivo experiments performed on diabetic rat models revealed the potential of the as-fabricated MNs to effectively pierce into the skin, leading to a notable hypoglycemic effect lasting up to 14 h without inducing the risk of hypoglycemia. These results indicate that the fabricated hollow-adjustable polymer MNs is a potential candidate for transdermal delivery of high-dose drugs.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Screening of Candidate Effectors from <i>Magnaporthe oryzae</i> by In Vitro Secretomic Analysis

Magnaporthe oryzae is the causal agent of rice blast, one of the most serious diseases of rice worldwide. Secreted proteins play essential roles during a M. oryzae–rice interaction. Although much progress has been made in recent decades, it is still necessary to systematically explore M. oryzae-secreted proteins and to analyze their functions. This study employs a shotgun-based proteomic analysis to investigate the in vitro secretome of M. oryzae by spraying fungus conidia onto the PVDF membrane to mimic the early stages of infection, during which 3315 non-redundant secreted proteins were identified. Among these proteins, 9.6% (319) and 24.7% (818) are classified as classically or non-classically secreted proteins, while the remaining 1988 proteins (60.0%) are secreted through currently unknown secretory pathway. Functional characteristics analysis show that 257 (7.8%) and 90 (2.7%) secreted proteins are annotated as CAZymes and candidate effectors, respectively. Eighteen candidate effectors are selected for further experimental validation. All 18 genes encoding candidate effectors are significantly up- or down-regulated during the early infection process. Sixteen of the eighteen candidate effectors cause the suppression of BAX-mediated cell death in Nicotiana benthamiana by using an Agrobacterium-mediated transient expression assay, suggesting their involvement in pathogenicity related to secretion effectors. Our results provide high-quality experimental secretome data of M. oryzae and will expand our knowledge on the molecular mechanisms of M. oryzae pathogenesis