Cross-Referencing Method for Scalable Public Blockchain

We previously proposed a cross-referencing method for enabling multiple peer-to-peer network domains to manage their own public blockchains and periodically exchanging the state of the latest fixed block in the blockchain with hysteresis signatures among all the domains via an upper network layer. In this study, we evaluated the effectiveness of our method from three theoretical viewpoints: decentralization, scalability, and tamper resistance. We show that the performance of the entire system can be improved because transactions and blocks are distributed only inside the domain. We argue that the transaction processing capacity will increase to 56,000 transactions per second, which is as much as that of a VISA credit card system. The capacity is also evaluated by multiplying the number of domains by the average reduction in transaction-processing time due to the increase in block size and reduction in the block-generation-time interval by domain partition. For tamper resistance, each domain has evidence of the hysteresis signatures of the other domains in the blockchain. We introduce two types of tamper-resistance-improvement ratios as evaluation measures of tamper resistance for a blockchain and theoretically explain how tamper resistance is improved using our cross-referencing method. With our method, tamper resistance improves as the number of domains increases. The proposed system of 1,000 domains are 3-10 times more tamper-resistant than that of 100 domains, and the capacity is 10 times higher. We conclude that our method enables a more scalable and tamper-resistant public blockchain balanced with decentralization.Comment: (29 pages, 18 figures, Internet of Things 15 (2021) 100419

The Creation of School Education Bringing up a Student Carrying Tomorrow (3) : The Valuation of "Compulsory Subjects", "Optional Subjects", and "Integrated Subjects"

The purpose of this study is to show the valuation of "Compulsory Subjects", "Optional Subjects", and "Integrated Subjects", to show the relationship between each subjects and "three abilities", "the ability of recognizing othere senses of value", "the ability of self-expression and communication" and "the ability of decision-making" which defined by the project members. The main result of this study is that we should make up the standards which teachers, students and parents recognize as important abilities

Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in Japan

In the initial phase of the novel coronavirus disease (COVID-19) pandemic, a large-scale cluster on the cruise ship Diamond Princess (DP) emerged in Japan. Genetic analysis of the DP strains has provided important information for elucidating the possible transmission process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on a cruise ship. However, genome-based analyses of SARS-CoV-2 detected in large-scale cruise ship clusters other than the DP cluster have rarely been reported. In the present study, whole-genome sequences of 94 SARS-CoV-2 strains detected in the second large cruise ship cluster, which emerged on the Costa Atlantica (CA) in Japan, were characterized to understand the evolution of the virus in a crowded and confined place. Phylogenetic and haplotype network analysis indicated that the CA strains were derived from a common ancestral strain introduced on the CA cruise ship and spread in a superspreading event-like manner, resulting in several mutations that might have affected viral characteristics, including the P681H substitution in the spike protein. Moreover, there were significant genetic distances between CA strains and other strains isolated in different environments, such as cities under lockdown. These results provide new insights into the unique evolution patterns of SARS-CoV-2 in the CA cruise ship cluster

Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in Japan

In the initial phase of the novel coronavirus disease (COVID-19) pandemic, a large-scale cluster on the cruise ship Diamond Princess (DP) emerged in Japan. Genetic analysis of the DP strains has provided important information for elucidating the possible transmission process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on a cruise ship. However, genome-based analyses of SARS-CoV-2 detected in large-scale cruise ship clusters other than the DP cluster have rarely been reported. In the present study, whole-genome sequences of 94 SARS-CoV-2 strains detected in the second large cruise ship cluster, which emerged on the Costa Atlantica (CA) in Japan, were characterized to understand the evolution of the virus in a crowded and confined place. Phylogenetic and haplotype network analysis indicated that the CA strains were derived from a common ancestral strain introduced on the CA cruise ship and spread in a superspreading event-like manner, resulting in several mutations that might have affected viral characteristics, including the P681H substitution in the spike protein. Moreover, there were significant genetic distances between CA strains and other strains isolated in different environments, such as cities under lockdown. These results provide new insights into the unique evolution patterns of SARS-CoV-2 in the CA cruise ship cluster