A Novel Model of Conforming Delaunay Triangulation for Sensor Network Configuration

Delaunay refinement is a technique for generating unstructured meshes of triangles for sensor network configuration engineering practice. A new method for solving Delaunay triangulation problem is proposed in this paper, which is called endpoint triangle’s circumcircle model (ETCM). As compared with the original fractional node refinement algorithms, the proposed algorithm can get well refinement stability with least time cost. Simulations are performed under five aspects including refinement stability, the number of additional nodes, time cost, mesh quality after intruding additional nodes, and the aspect ratio improved by single additional node. All experimental results show the advantages of the proposed algorithm as compared with the existing algorithms and confirm the algorithm analysis sufficiently

Candidate Galaxies at z ~ 11.3--21.8 and beyond: results from JWST's public data taken in its first year

We present a systematic search of candidate galaxies at z > 11.3 using the public Near Infrared Camera data taken by the James Webb Space Telescope (JWST) in its Cycle 1, which include six blank fields totalling 386 sq.arcmin and two lensing cluster fields totalling 48 sq.arcmin. The candidates are selected as F150W, F200W and F277W dropouts, which correspond to z ~ 12.7 (11.3 < z < 15.4), 17.3 (15.4 < z < 21.8) and 24.7 (21.8 < z < 28.3), respectively. Our sample consists of 123 F150W dropouts, 52 F200W dropouts and 32 F277W dropouts, which is the largest candidate galaxy sample probing the highest redshift range to date. The F150W and F200W dropouts have sufficient photometric information that allows contaminant rejection, which we do by fitting to their spectrum energy distributions. Based on the purified samples of F150W and F200W dropouts, we derive galaxy luminosity functions at z ~ 12.7 and 17.3, respectively. We find that both are better described by power law than Schechter function and that there is only a marginal evolution (a factor of < 2) between the two epochs. The emergence of galaxy population at z ~ 17.3 or earlier is consistent with the suggestion of an early cosmic hydrogen reionization and is not necessarily a crisis of the LCDM paradigm. To establish a new picture of galaxy formation in the early universe, we will need both JWST spectroscopic confirmation of bright candidates such as those in our sample and deeper surveys to further constrain the faint-end of the luminosity function at M > -18 mag.Comment: Submitted to Ap

T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity.

BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM. METHODS: Vascular segments were isolated from WT or T-cad knockout mice. Endothelial function, total NO accumulation, and the expression of T-cad related proteins were determined. RESULTS: Ach and acidified NaNO2 induced similar vasorelaxation in WT groups. T-cad KO mice exhibited normal response to acidified NaNO2, but manifested markedly reduced response to Ach. NO accumulation was also decreased in T-cad KO group. T-cad expression was reduced in WT mice fed 8 weeks of high fat diet (HFD). Furthermore, exacerbated reduction of vasorelaxation was observed in T-cad KO mice fed 8 weeks of HFD. CONCLUSIONS: In the current study, we provide the first in vivo evidence that T-cadherin deficiency causes endothelial dysfunction in T2DM vascular segments, suggesting the involvement of T-cad deficiency in T2DM pathogenesis