Characteristics of the studies included in meta-analysis.

<p>NA, data not available; CAD, coronary artery disease; AMI, acute myocardial infarction; MI, myocardial infarction; SSCP, single-strand conformation polymorphism; RFLP, restriction fragment length polymorphisms; PCR-SSP, polymerase chain reaction with sequence-specific primers.</p>§<p>Gender component: number of male cases/number of female cases/number of male controls/number of female controls.</p

Univariable meta regression analysis for heterogeneity under the additive model.

<p>CA, coronary angiography; HWE, Hardy-Weinberg equilibrium; RFLP, restriction fragment length polymorphisms.</p

Description of search strategy for electronic databases.

<p>Description of search strategy for electronic databases.</p

Summary odds ratio (95%CI) and I² for G-403A polymorphism and coronary artery disease under additive, recessive and dominant model.

<p>NA,data not available; CA, coronary angiography; HWE, Hardy-Weinberg equilibrium;</p><p>RFLP, restriction fragment length polymorphisms.</p>§<p>N:The number of studies included in subgroup.</p

The distribution of RANTES genotype among cases and controls included in meta-analysis.

<p>NA, data not available; CAD, coronary artery disease; HWE, Hardy-Weinberg equilibrium.</p

Begg’s funnel plot of publication bias with pseudo 95% confidence limits.

<p>The horizontal line in the funnel plot indicates the random effects summary estimate, while the sloping lines indicate the expected 95% confidence intervals for a given standard error, assuming no heterogeneity between studies. Each study is represented by a circle, the area of which represents the study’s precision. A, Additive model (Egger’s test P = 0.643). B, Recessive model (Egger’s test P = 0.020 ). C, Dominant model (Egger’s test P = 0.519). D, AA versus GG (Egger’s test P = 0.014). E, GA versus GG (Egger’s test P = 0.429).</p

Summary OR (95%CI) and I² for G-403A polymorphism and coronary artery disease under AA vs GG and GA vs GG contrasts.

<p>Abbreviations as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047211#pone-0047211-t004" target="_blank">Table 4</a>.</p>§<p>N:The number of studies included in subgroup.</p

Results of association between the G-403A polymorphism and coronary artery disease.

<p>The overall odds ratio (OR) was estimated with DerSimonian-Laird random effects model. The ORs of individual studies are shown as squares, with the size proportional to the weight of each study in the overall estimate; 95% confidence intervals (CIs) are shown as horizontal lines. The pooled OR and its 95% CI are shown as a dashed vertical line and a diamond, respectively. A, Additive model. B, Recessive model. C, Dominant model. D, AA versus GG. E, GA versus GG.</p