A spectral line survey of IRC +10216 between 13.3 and 18.5 GHz

A spectral line survey of IRC +10216 between 13.3 and 18.5 GHz is carried out using the Shanghai Tian Ma 65 m Radio Telescope (TMRT-65m) with a sensitivity of < 7 mK. Thirty-five spectral lines of 12 different molecules and radicals are detected in total. Except for SiS, the detected molecules are all carbon-chain molecules, including HC3N, HC5N, HC7N, HC9N, C6H, C6H-, C8H, SiC2, SiC4, c-C3H2 and l-C5H. The presence of rich carbon-bearing molecules is consistent with the identity of IRC +10216 as a carbon-rich AGB star. The excitation temperatures and column densities of the observed species are derived by assuming a local thermodynamic equilibrium and homogeneous conditions.Comment: This is the authors' version of the manuscript; 16 pages, 5 figures, 6 tables; Accepted for publication in A&A 8/17/201

Neoadjuvant Chemotherapy with FOLFOX4 Regimen to Treat Advanced Gastric Cancer Improves Survival without Increasing Adverse Events: A Retrospective Cohort Study from a Chinese Center

Background/Aim. To evaluate the clinical efficacy of FOLFOX4 (5-fluomumcil/leucovorin combined and oxaliplatin) neoadjuvant chemotherapy for advanced gastric cancer (AGC). Patients and Methods. Fifty-eight AGC patients were enrolled in this retrospective cohort study, 23 in the neoadjuvant group and 35 in the adjuvant group. R0 resection, survival, and adverse events were compared. Results. The two groups were well-matched, with no significant differences in R0 resection rate (82.6% versus 82.0%) and number of lymph nodes dissection (16 (0–49) versus 13 (3–40)) between the two groups (P>0.05). The number of lymph node metastases in the neoadjuvant group (3 (0–14)) was significantly fewer than that in the adjuvant group (6 (0–27)) (P=0.04). The neoadjuvant group had significantly better median overall survival (29.0 versus 22.0 months) and 3-year survival rate (73.9% versus 40.0%) than the adjuvant group (P=0.013). The positive expression rate of Ki-67 in the neoadjuvant group (40.0%, 8/20) was lower than that in the adjuvant group (74.2%, 23/31; P=0.015). Conclusion. The FOLFOX4 neoadjuvant chemotherapy could improve survival without increasing adverse events in patients with AGC

Biased compensation recursive least squares-based threshold algorithm for time-delay rational models via redundant rule

© 2017, Springer Science+Business Media B.V., part of Springer Nature. This paper develops a biased compensation recursive least squares-based threshold algorithm for a time-delay rational model. The time-delay rational model is transformed into an augmented model by using the redundant rule, and then, a recursive least squares algorithm is proposed to estimate the parameters of the augmented model. Since the output of the augmented model is correlated with the noise, a biased compensation method is derived to eliminate the bias of the parameter estimates. Furthermore, based on the structures of the augmented model parameter vector and the rational model parameter vector, the unknown time delay can be computed by using a threshold given in prior. A simulated example is used to illustrate the efficiency of the proposed algorithm

Cryptanalysis of the Hillery-Buzek-Berthiaume quantum secret-sharing protocol

The participant attack is the most serious threat for quantum secret-sharing protocols. We present a method to analyze the security of quantum secret-sharing protocols against this kind of attack taking the scheme of Hillery, Buzek, and Berthiaume (HBB) [Phys. Rev. A 59 1829 (1999)] as an example. By distinguishing between two mixed states, we derive the necessary and sufficient conditions under which a dishonest participant can attain all the information without introducing any error, which shows that the HBB protocol is insecure against dishonest participants. It is easy to verify that the attack scheme of Karlsson, Koashi, and Imoto [Phys. Rev. A 59, 162 (1999)] is a special example of our results. To demonstrate our results further, we construct an explicit attack scheme according to the necessary and sufficient conditions. Our work completes the security analysis of the HBB protocol, and the method presented may be useful for the analysis of other similar protocols.Comment: Revtex, 7 pages, 3 figures; Introduction modifie

Study on Optimization of Product Processing of Pyruvic Acid Its Separation and Purification

The preparation of pyruvic acid from lactic acid with hydrogen peroxide as the oxidant and ferrous sulfate as the catalyst was carried out with the ratio of lactic acid and hydrogen peroxide being 1:1.1 the reaction was processed at 40 ℃ and the amount of ferrous sulfate was 1.5g. After 4 hours, raw product of pyruvic acid was taken and the separation and purification process started using an ion exchanging resin D315 then vacuum distillation respectively and pyruvic acid content was determined by the UV spectrophotometer. Keywords: lactic acid; pyruvic acid; catalytic oxidation; UV spectrophotometer

The Biological Behaviors of Rat Dermal Fibroblasts Can Be Inhibited by High Levels of MMP9

Aims. To explore the effects of the high expression of MMP9 on biological behaviors of fibroblasts. Methods. High glucose and hyperhomocysteine were used to induce MMP9 expression in skin fibroblasts. Cell proliferation was detected by flow cytometry and cell viability by CCK-8. ELISA assay was used to detect collagen (hydroxyproline) secretion. Scratch test was employed to evaluate horizontal migration of cells and transwell method to evaluate vertical migration of cells. Results. The mRNA and protein expressions of MMP9 and its protease activity were significantly higher in cells treated with high glucose and hyperhomocysteine than those in control group. At the same time, the S-phase cell ratio, proliferation index, cell viability, collagen (hydroxyproline) secretion, horizontal migration rate, and the number of vertical migration cells decreased in high-glucose and hyperhomocysteine-treated group. Tissue inhibitor of metalloproteinase 1 (TIMP1), which inhibits the activity of MMP9, recovered the above biological behaviors. Conclusions. High expression of MMP9 in skin fibroblasts could be induced by cultureing in high glucose and hyperhomocysteine medium, which inhibited cell biological behaviors. Inhibitions could be reversed by TIMP1. The findings suggested that MMP9 deters the healing of diabetic foot ulcers by inhibiting the biological behaviors of fibroblasts